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Protein
Submitted name:

cDNA FLJ52521, highly similar to Actin-like protein 3

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro

GO - Biological processi

  1. Arp2/3 complex-mediated actin nucleation Source: InterPro
  2. asymmetric cell division Source: Ensembl
  3. establishment or maintenance of cell polarity Source: Ensembl
  4. meiotic chromosome movement towards spindle pole Source: Ensembl
  5. meiotic cytokinesis Source: Ensembl
  6. positive regulation of dendrite morphogenesis Source: Ensembl
  7. positive regulation of filopodium assembly Source: Ensembl
  8. positive regulation of lamellipodium assembly Source: Ensembl
  9. regulation of myosin II filament organization Source: Ensembl
  10. response to antibiotic Source: Ensembl
  11. response to carbohydrate Source: Ensembl
  12. spindle localization Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

SignaLinkiB4DTI0.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52521, highly similar to Actin-like protein 3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. actin filament Source: Ensembl
  2. Arp2/3 protein complex Source: InterPro
  3. cell-cell junction Source: Ensembl
  4. excitatory synapse Source: Ensembl
  5. Golgi membrane Source: Ensembl
  6. hemidesmosome Source: Ensembl
  7. lamellipodium Source: Ensembl
  8. podosome Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB4DTI0.

Expressioni

Gene expression databases

BgeeiB4DTI0.
ExpressionAtlasiB4DTI0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB4DTI0.
SMRiB4DTI0. Positions 1-288.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG003771.

Family and domain databases

InterProiIPR004000. Actin.
IPR015623. Arp3.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PTHR11937:SF175. PTHR11937:SF175. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DTI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFESFNVPGL YIAVQAVLAL AASWTSRQVG ERTLTGTVID SGDGVTHVIP
60 70 80 90 100
VAEGYVIGSC IKHIPIAGRD ITYFIQQLLR DREVGIPPEQ SLETAKAVKE
110 120 130 140 150
RYSYVCPDLV KEFNKYDTDG SKWIKQYTGI NAISKKEFSI DVGYERFLGP
160 170 180 190 200
EIFFHPEFAN PDFTQPISEV VDEVIQNCPI DVRRPLYKNI VLSGGSTMFR
210 220 230 240 250
DFGRRLQRDL KRTVDARLKL SEELSGGRLK PKPIDVQVIT HHMQRYAVWF
260 270 280
GGSMLASTPE FYQVCHTKKD YEEIGPSICR HNPVFGVMS
Length:289
Mass (Da):32,656
Last modified:September 23, 2008 - v1
Checksum:iC920EF651D740F7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300224 mRNA. Translation: BAG61992.1.
UniGeneiHs.433512.
Hs.595349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300224 mRNA. Translation: BAG61992.1.
UniGeneiHs.433512.
Hs.595349.

3D structure databases

ProteinModelPortaliB4DTI0.
SMRiB4DTI0. Positions 1-288.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB4DTI0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG003771.

Enzyme and pathway databases

SignaLinkiB4DTI0.

Miscellaneous databases

NextBioi35474940.

Gene expression databases

BgeeiB4DTI0.
ExpressionAtlasiB4DTI0. baseline and differential.

Family and domain databases

InterProiIPR004000. Actin.
IPR015623. Arp3.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PTHR11937:SF175. PTHR11937:SF175. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: PlacentaImported.

Entry informationi

Entry nameiB4DTI0_HUMAN
AccessioniPrimary (citable) accession number: B4DTI0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 4, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.