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Protein
Submitted name:

Myotilin

Gene

MYOT

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
MyotilinImported
Submitted name:
cDNA FLJ52421, highly similar to MyotilinImported
Gene namesi
Name:MYOTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:12399. MYOT.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120729.

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DT68.
PRIDEiB4DT68.

Expressioni

Gene expression databases

BgeeiENSG00000120729.
ExpressionAtlasiB4DT68. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000239926.

Structurei

3D structure databases

ProteinModelPortaliB4DT68.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini135 – 220Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST86
Domaini234 – 326Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST93

Phylogenomic databases

eggNOGiENOG410IG16. Eukaryota.
ENOG410ZZ78. LUCA.
GeneTreeiENSGT00840000129779.
HOGENOMiHOG000028074.
HOVERGENiHBG066530.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF07679. I-set. 2 hits.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DT68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSNYQQSSA GQPINAKPSQ TANAKPIPRT PDHEIQGSKE ALIQDLERKL
60 70 80 90 100
KCKDTLLHNG NQRLTYEEKM ARRLLGPQNA AAVFQAQDDS GAQDSQQHNS
110 120 130 140 150
EHARLQVPTS QVRSRSTSRG DVNDQDAIQE KFYPPRFIQV PENMSIDEGR
160 170 180 190 200
FCRMDFKVSG LPAPDVSWYL NGRTVQSDDL HKMIVSEKGL HSLIFEVVRA
210 220 230 240 250
SDAGAYACVA KNRAGEATFT VQLDVLAKEH KRAPMFIYKP QSKKVLEGDS
260 270 280 290 300
VKLECQISAI PPPKLFWKRN NEMVQFNTDR ISLYQDNTGR VTLLIKDVNK
310 320 330 340 350
KDAGWYTVSA VNEAGVTTCN TRLDVTARPN QTLPAPKQLR VRPTFSKYLA
360 370 380
LNGKGLNVKQ AFNPEGEFQR LAAQSGLYES EEL
Length:383
Mass (Da):42,904
Last modified:September 23, 2008 - v1
Checksum:iBCE8A970CE3AF5DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106791 Genomic DNA. No translation available.
KF459595 Genomic DNA. No translation available.
AK300076 mRNA. Translation: BAG61880.1.
RefSeqiNP_001287840.1. NM_001300911.1.
UniGeneiHs.84665.

Genome annotation databases

EnsembliENST00000515645; ENSP00000426281; ENSG00000120729.
GeneIDi9499.
UCSCiuc011cyh.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106791 Genomic DNA. No translation available.
KF459595 Genomic DNA. No translation available.
AK300076 mRNA. Translation: BAG61880.1.
RefSeqiNP_001287840.1. NM_001300911.1.
UniGeneiHs.84665.

3D structure databases

ProteinModelPortaliB4DT68.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000239926.

Proteomic databases

PeptideAtlasiB4DT68.
PRIDEiB4DT68.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000515645; ENSP00000426281; ENSG00000120729.
GeneIDi9499.
UCSCiuc011cyh.3. human.

Organism-specific databases

CTDi9499.
HGNCiHGNC:12399. MYOT.
OpenTargetsiENSG00000120729.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IG16. Eukaryota.
ENOG410ZZ78. LUCA.
GeneTreeiENSGT00840000129779.
HOGENOMiHOG000028074.
HOVERGENiHBG066530.

Miscellaneous databases

ChiTaRSiMYOT. human.
GenomeRNAii9499.

Gene expression databases

BgeeiENSG00000120729.
ExpressionAtlasiB4DT68. baseline and differential.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PfamiPF07679. I-set. 2 hits.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DT68_HUMAN
AccessioniPrimary (citable) accession number: B4DT68
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 2, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.