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Protein
Submitted name:

cDNA FLJ50658, highly similar to T-cell surface glycoprotein CD4

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50658, highly similar to T-cell surface glycoprotein CD4Imported
Submitted name:
cDNA, FLJ79360, highly similar to T-cell surface glycoprotein CD4Imported
Submitted name:
cDNA, FLJ79361, highly similar to T-cell surface glycoprotein CD4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei124 – 147HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DT49.
PRIDEiB4DT49.

Expressioni

Gene expression databases

BgeeiENSG00000010610.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000011653.

Structurei

3D structure databases

ProteinModelPortaliB4DT49.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 43CD4-extracelInterPro annotationAdd BLAST43
Domaini44 – 115C2-setInterPro annotationAdd BLAST72
Domaini153 – 180Tcell_CD4_CInterPro annotationAdd BLAST28

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.
HOVERGENiHBG087154.
KOiK06454.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR000973. CD4.
IPR015274. CD4-extracel.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR021963. Tcell_CD4_Cterm.
[Graphical view]
PANTHERiPTHR11422:SF0. PTHR11422:SF0. 1 hit.
PfamiPF05790. C2-set. 1 hit.
PF09191. CD4-extracel. 1 hit.
PF12104. Tcell_CD4_C. 1 hit.
[Graphical view]
PRINTSiPR00692. CD4TCANTIGEN.
SUPFAMiSSF48726. SSF48726. 2 hits.

Sequencei

Sequence statusi: Complete.

B4DT49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKKLPLHLT LPQALPQYAG SGNLTLALEA KTGKLHQEVN LVVMRATQLQ
60 70 80 90 100
KNLTCEVWGP TSPKLMLSLK LENKEAKVSK REKAVWVLNP EAGMWQCLLS
110 120 130 140 150
DSGQVLLESN IKVLPTWSTP VQPMALIVLG GVAGLLLFIG LGIFFCVRCR
160 170 180
HRRRQAERMS QIKRLLSEKK TCQCPHRFQK TCSPI
Length:185
Mass (Da):20,680
Last modified:September 23, 2008 - v1
Checksum:iE1AA40F9EDD032A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300052 mRNA. Translation: BAG61861.1.
AK316461 mRNA. Translation: BAH14832.1.
AK316462 mRNA. Translation: BAH14833.1.
RefSeqiNP_000607.1. NM_000616.4.
NP_001181943.1. NM_001195014.2.
NP_001181944.1. NM_001195015.2.
NP_001181945.1. NM_001195016.2.
NP_001181946.1. NM_001195017.2.
XP_016875717.1. XM_017020228.1.
UniGeneiHs.631659.

Genome annotation databases

GeneIDi920.
KEGGihsa:920.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300052 mRNA. Translation: BAG61861.1.
AK316461 mRNA. Translation: BAH14832.1.
AK316462 mRNA. Translation: BAH14833.1.
RefSeqiNP_000607.1. NM_000616.4.
NP_001181943.1. NM_001195014.2.
NP_001181944.1. NM_001195015.2.
NP_001181945.1. NM_001195016.2.
NP_001181946.1. NM_001195017.2.
XP_016875717.1. XM_017020228.1.
UniGeneiHs.631659.

3D structure databases

ProteinModelPortaliB4DT49.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000011653.

Proteomic databases

PeptideAtlasiB4DT49.
PRIDEiB4DT49.

Protocols and materials databases

DNASUi920.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi920.
KEGGihsa:920.

Organism-specific databases

CTDi920.

Phylogenomic databases

eggNOGiENOG410IK9F. Eukaryota.
ENOG410YWI4. LUCA.
HOVERGENiHBG087154.
KOiK06454.

Miscellaneous databases

GenomeRNAii920.

Gene expression databases

BgeeiENSG00000010610.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR000973. CD4.
IPR015274. CD4-extracel.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR021963. Tcell_CD4_Cterm.
[Graphical view]
PANTHERiPTHR11422:SF0. PTHR11422:SF0. 1 hit.
PfamiPF05790. C2-set. 1 hit.
PF09191. CD4-extracel. 1 hit.
PF12104. Tcell_CD4_C. 1 hit.
[Graphical view]
PRINTSiPR00692. CD4TCANTIGEN.
SUPFAMiSSF48726. SSF48726. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiB4DT49_HUMAN
AccessioniPrimary (citable) accession number: B4DT49
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 2, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.