B4DT49 (B4DT49_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ50658, highly similar to T-cell surface glycoprotein CD4 EMBL BAG61861.1 Submitted name: cDNA, FLJ79360, highly similar to T-cell surface glycoprotein CD4 EMBL BAH14832.1 Submitted name: cDNA, FLJ79361, highly similar to T-cell surface glycoprotein CD4 EMBL BAH14833.1
Organism	Homo sapiens (Human) EMBL BAG61861.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	T cell activation Inferred from electronic annotation. Source: Compara cell adhesion Inferred from electronic annotation. Source: InterPro cell surface receptor signaling pathway Inferred from electronic annotation. Source: Compara cytokine production Inferred from electronic annotation. Source: Compara defense response to Gram-negative bacterium Inferred from electronic annotation. Source: Compara immune response Inferred from electronic annotation. Source: InterPro positive regulation of T cell activation Inferred from electronic annotation. Source: Compara positive regulation of calcium-mediated signaling Inferred from electronic annotation. Source: Compara positive regulation of peptidyl-tyrosine phosphorylation Inferred from electronic annotation. Source: Compara
Cellular_component	endoplasmic reticulum lumen Inferred from electronic annotation. Source: Compara endoplasmic reticulum membrane Inferred from electronic annotation. Source: Compara external side of plasma membrane Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: InterPro membrane raft Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DT49 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: E1AA40F9EDD032A5	FASTA	185	20,680
	10 20 30 40 50 60 MGKKLPLHLT LPQALPQYAG SGNLTLALEA KTGKLHQEVN LVVMRATQLQ KNLTCEVWGP 70 80 90 100 110 120 TSPKLMLSLK LENKEAKVSK REKAVWVLNP EAGMWQCLLS DSGQVLLESN IKVLPTWSTP 130 140 150 160 170 180 VQPMALIVLG GVAGLLLFIG LGIFFCVRCR HRRRQAERMS QIKRLLSEKK TCQCPHRFQK TCSPI

References

[1]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Thymus EMBL BAH14832.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK300052 mRNA. Translation: BAG61861.1. AK316461 mRNA. Translation: BAH14832.1. AK316462 mRNA. Translation: BAH14833.1.
IPI	IPI00975822.
RefSeq	NP_000607.1. NM_000616.4. NP_001181943.1. NM_001195014.2. NP_001181944.1. NM_001195015.2. NP_001181945.1. NM_001195016.2. NP_001181946.1. NM_001195017.2.
UniGene	Hs.631659.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4DT49.
Protocols and materials databases
DNASU	920.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	920.
KEGG	hsa:920.
UCSC	uc010sfj.2. human.
Organism-specific databases
CTD	920.
Phylogenomic databases
HOVERGEN	HBG087154.
KO	K06454.
Gene expression databases
ArrayExpress	B4DT49.
Bgee	B4DT49.
Family and domain databases
Gene3D	2.60.40.10. 2 hits.
InterPro	IPR000973. Ag_CD4. IPR015274. CD4-extracel. IPR013783. Ig-like_fold. IPR008424. Ig_C2-set. IPR021963. Tcell_CD4_Cterm. [Graphical view]
Pfam	PF05790. C2-set. 1 hit. PF09191. CD4-extracel. 1 hit. PF12104. Tcell_CD4_Cterm. 1 hit. [Graphical view]
PRINTS	PR00692. CD4TCANTIGEN.
ProtoNet	Search...
Other
GenomeRNAi	920.
NextBio	3806.

Entry information

Entry name

B4DT49_HUMAN

Accession

Primary (citable) accession number: B4DT49

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	March 6, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.