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B4DSI8

- B4DSI8_HUMAN

UniProt

B4DSI8 - B4DSI8_HUMAN

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Protein
Submitted name: cDNA FLJ60344, highly similar to Probable global transcription activator SNF2L4 (EC 3.6.1.-)
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl
  3. chromatin binding Source: Ensembl
  4. helicase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. DNA methylation on cytosine within a CG sequence Source: Ensembl
  2. aortic smooth muscle cell differentiation Source: Ensembl
  3. blastocyst growth Source: Ensembl
  4. blastocyst hatching Source: Ensembl
  5. cell morphogenesis Source: Ensembl
  6. chromatin remodeling Source: Ensembl
  7. definitive erythrocyte differentiation Source: Ensembl
  8. embryonic hindlimb morphogenesis Source: Ensembl
  9. embryonic organ morphogenesis Source: Ensembl
  10. epidermis morphogenesis Source: Ensembl
  11. extracellular matrix organization Source: Ensembl
  12. forebrain development Source: Ensembl
  13. glial cell fate determination Source: Ensembl
  14. heart trabecula formation Source: Ensembl
  15. hindbrain development Source: Ensembl
  16. histone H3 acetylation Source: Ensembl
  17. keratinocyte differentiation Source: Ensembl
  18. liver development Source: Ensembl
  19. methylation-dependent chromatin silencing Source: Ensembl
  20. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  21. positive regulation of DNA binding Source: Ensembl
  22. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  23. stem cell maintenance Source: Ensembl
  24. vasculogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ60344, highly similar to Probable global transcription activator SNF2L4 (EC 3.6.1.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. heterochromatin Source: Ensembl
  2. nBAF complex Source: Ensembl
  3. npBAF complex Source: Ensembl
  4. nuclear euchromatin Source: Ensembl
  5. perichromatin fibrils Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB4DSI8.

Expressioni

Gene expression databases

ArrayExpressiB4DSI8.
BgeeiB4DSI8.

Family & Domainsi

Keywords - Domaini

BromodomainSAAS annotations

Phylogenomic databases

HOVERGENiHBG056636.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR029295. SnAC.
IPR000330. SNF2_N.
[Graphical view]
PfamiPF00439. Bromodomain. 1 hit.
PF00271. Helicase_C. 1 hit.
PF14619. SnAC. 1 hit.
PF00176. SNF2_N. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DSI8-1 [UniParc]FASTAAdd to Basket

« Hide

MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV    50
KVSYKGSPAA RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV 100
DEGHRMKNHH CKLTQVLNTH YVAPRRLLLT GTPLQNKLPE LWALLNFLLP 150
TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE TILIIRRLHK VLRPFLLRRL 200
KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD GSEKDKKGKG 250
GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG 300
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT 350
KAEDRGMLLK TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP 400
HQDLQAQDRA HRIGQQNEVR VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ 450
AGMFDQKSSS HERRAFLQAI LEHEEQDESR HCSTGSGSAS FAHTAPPPAG 500
VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD LDRRREEARN 550
PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS 600
DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS 650
RDKDDESKKQ KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ 700
LSEVFIQLPS RKELPEYYEL IRKPVDFKKI KERIRNHKYR SLNDLEKDVM 750
LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV RQKIEKEDDS EGEESEEEEE 800
GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS RAKPVVSDDD 850
SEEEQEEDRS GSGSEED 867
Length:867
Mass (Da):100,153
Last modified:September 23, 2008 - v1
Checksum:i4E0298E6F27F051F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK299761 mRNA. Translation: BAG61650.1.
UniGeneiHs.327527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK299761 mRNA. Translation: BAG61650.1 .
UniGenei Hs.327527.

3D structure databases

ModBasei Search...

Proteomic databases

PRIDEi B4DSI8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG056636.

Miscellaneous databases

NextBioi 35474677.

Gene expression databases

ArrayExpressi B4DSI8.
Bgeei B4DSI8.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
3.40.50.300. 2 hits.
InterProi IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR029295. SnAC.
IPR000330. SNF2_N.
[Graphical view ]
Pfami PF00439. Bromodomain. 1 hit.
PF00271. Helicase_C. 1 hit.
PF14619. SnAC. 1 hit.
PF00176. SNF2_N. 1 hit.
[Graphical view ]
PRINTSi PR00503. BROMODOMAIN.
SMARTi SM00297. BROMO. 1 hit.
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view ]
SUPFAMi SSF47370. SSF47370. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEi PS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB4DSI8_HUMAN
AccessioniPrimary (citable) accession number: B4DSI8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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