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B4DSI8

- B4DSI8_HUMAN

UniProt

B4DSI8 - B4DSI8_HUMAN

Protein
Submitted name:

cDNA FLJ60344, highly similar to Probable global transcription activator SNF2L4 (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. chromatin binding Source: Ensembl
    3. helicase activity Source: InterPro
    4. RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl

    GO - Biological processi

    1. aortic smooth muscle cell differentiation Source: Ensembl
    2. blastocyst growth Source: Ensembl
    3. blastocyst hatching Source: Ensembl
    4. cell morphogenesis Source: Ensembl
    5. chromatin remodeling Source: Ensembl
    6. definitive erythrocyte differentiation Source: Ensembl
    7. DNA methylation on cytosine within a CG sequence Source: Ensembl
    8. embryonic hindlimb morphogenesis Source: Ensembl
    9. embryonic organ morphogenesis Source: Ensembl
    10. epidermis morphogenesis Source: Ensembl
    11. extracellular matrix organization Source: Ensembl
    12. forebrain development Source: Ensembl
    13. glial cell fate determination Source: Ensembl
    14. heart trabecula formation Source: Ensembl
    15. hindbrain development Source: Ensembl
    16. histone H3 acetylation Source: Ensembl
    17. keratinocyte differentiation Source: Ensembl
    18. liver development Source: Ensembl
    19. methylation-dependent chromatin silencing Source: Ensembl
    20. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
    21. positive regulation of DNA binding Source: Ensembl
    22. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    23. stem cell maintenance Source: Ensembl
    24. vasculogenesis Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ60344, highly similar to Probable global transcription activator SNF2L4 (EC 3.6.1.-)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. heterochromatin Source: Ensembl
    2. nBAF complex Source: Ensembl
    3. npBAF complex Source: Ensembl
    4. nuclear euchromatin Source: Ensembl
    5. perichromatin fibrils Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiB4DSI8.

    Expressioni

    Gene expression databases

    ArrayExpressiB4DSI8.
    BgeeiB4DSI8.

    Family & Domainsi

    Keywords - Domaini

    BromodomainSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG056636.

    Family and domain databases

    Gene3Di1.20.920.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProiIPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR014001. Helicase_ATP-bd.
    IPR001650. Helicase_C.
    IPR027417. P-loop_NTPase.
    IPR029295. SnAC.
    IPR000330. SNF2_N.
    [Graphical view]
    PfamiPF00439. Bromodomain. 1 hit.
    PF00271. Helicase_C. 1 hit.
    PF14619. SnAC. 1 hit.
    PF00176. SNF2_N. 1 hit.
    [Graphical view]
    PRINTSiPR00503. BROMODOMAIN.
    SMARTiSM00297. BROMO. 1 hit.
    SM00487. DEXDc. 1 hit.
    SM00490. HELICc. 1 hit.
    [Graphical view]
    SUPFAMiSSF47370. SSF47370. 1 hit.
    SSF52540. SSF52540. 2 hits.
    PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    PS51192. HELICASE_ATP_BIND_1. 1 hit.
    PS51194. HELICASE_CTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4DSI8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV    50
    KVSYKGSPAA RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV 100
    DEGHRMKNHH CKLTQVLNTH YVAPRRLLLT GTPLQNKLPE LWALLNFLLP 150
    TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE TILIIRRLHK VLRPFLLRRL 200
    KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD GSEKDKKGKG 250
    GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG 300
    KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT 350
    KAEDRGMLLK TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP 400
    HQDLQAQDRA HRIGQQNEVR VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ 450
    AGMFDQKSSS HERRAFLQAI LEHEEQDESR HCSTGSGSAS FAHTAPPPAG 500
    VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD LDRRREEARN 550
    PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS 600
    DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS 650
    RDKDDESKKQ KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ 700
    LSEVFIQLPS RKELPEYYEL IRKPVDFKKI KERIRNHKYR SLNDLEKDVM 750
    LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV RQKIEKEDDS EGEESEEEEE 800
    GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS RAKPVVSDDD 850
    SEEEQEEDRS GSGSEED 867
    Length:867
    Mass (Da):100,153
    Last modified:September 23, 2008 - v1
    Checksum:i4E0298E6F27F051F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK299761 mRNA. Translation: BAG61650.1.
    UniGeneiHs.327527.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK299761 mRNA. Translation: BAG61650.1 .
    UniGenei Hs.327527.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B4DSI8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG056636.

    Miscellaneous databases

    NextBioi 35474677.

    Gene expression databases

    ArrayExpressi B4DSI8.
    Bgeei B4DSI8.

    Family and domain databases

    Gene3Di 1.20.920.10. 1 hit.
    3.40.50.300. 2 hits.
    InterProi IPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR014001. Helicase_ATP-bd.
    IPR001650. Helicase_C.
    IPR027417. P-loop_NTPase.
    IPR029295. SnAC.
    IPR000330. SNF2_N.
    [Graphical view ]
    Pfami PF00439. Bromodomain. 1 hit.
    PF00271. Helicase_C. 1 hit.
    PF14619. SnAC. 1 hit.
    PF00176. SNF2_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00503. BROMODOMAIN.
    SMARTi SM00297. BROMO. 1 hit.
    SM00487. DEXDc. 1 hit.
    SM00490. HELICc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47370. SSF47370. 1 hit.
    SSF52540. SSF52540. 2 hits.
    PROSITEi PS00633. BROMODOMAIN_1. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    PS51192. HELICASE_ATP_BIND_1. 1 hit.
    PS51194. HELICASE_CTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiB4DSI8_HUMAN
    AccessioniPrimary (citable) accession number: B4DSI8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.