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B4DSI8

- B4DSI8_HUMAN

UniProt

B4DSI8 - B4DSI8_HUMAN

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Protein
Submitted name:

cDNA FLJ60344, highly similar to Probable global transcription activator SNF2L4 (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. chromatin binding Source: Ensembl
  3. RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl

GO - Biological processi

  1. aortic smooth muscle cell differentiation Source: Ensembl
  2. blastocyst growth Source: Ensembl
  3. blastocyst hatching Source: Ensembl
  4. cell morphogenesis Source: Ensembl
  5. chromatin remodeling Source: Ensembl
  6. definitive erythrocyte differentiation Source: Ensembl
  7. DNA methylation on cytosine within a CG sequence Source: Ensembl
  8. embryonic hindlimb morphogenesis Source: Ensembl
  9. embryonic organ morphogenesis Source: Ensembl
  10. epidermis morphogenesis Source: Ensembl
  11. extracellular matrix organization Source: Ensembl
  12. forebrain development Source: Ensembl
  13. glial cell fate determination Source: Ensembl
  14. heart trabecula formation Source: Ensembl
  15. hindbrain development Source: Ensembl
  16. histone H3 acetylation Source: Ensembl
  17. keratinocyte differentiation Source: Ensembl
  18. lens fiber cell development Source: Ensembl
  19. liver development Source: Ensembl
  20. methylation-dependent chromatin silencing Source: Ensembl
  21. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  22. positive regulation of DNA binding Source: Ensembl
  23. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  24. stem cell maintenance Source: Ensembl
  25. vasculogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ60344, highly similar to Probable global transcription activator SNF2L4 (EC 3.6.1.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. heterochromatin Source: Ensembl
  2. nBAF complex Source: Ensembl
  3. npBAF complex Source: Ensembl
  4. nuclear euchromatin Source: Ensembl
  5. perichromatin fibrils Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB4DSI8.

Expressioni

Gene expression databases

BgeeiB4DSI8.
ExpressionAtlasiB4DSI8. baseline and differential.

Family & Domainsi

Keywords - Domaini

BromodomainSAAS annotation

Phylogenomic databases

HOVERGENiHBG056636.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR029295. SnAC.
IPR000330. SNF2_N.
[Graphical view]
PfamiPF00439. Bromodomain. 1 hit.
PF00271. Helicase_C. 1 hit.
PF14619. SnAC. 1 hit.
PF00176. SNF2_N. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DSI8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV
60 70 80 90 100
KVSYKGSPAA RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV
110 120 130 140 150
DEGHRMKNHH CKLTQVLNTH YVAPRRLLLT GTPLQNKLPE LWALLNFLLP
160 170 180 190 200
TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE TILIIRRLHK VLRPFLLRRL
210 220 230 240 250
KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD GSEKDKKGKG
260 270 280 290 300
GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
310 320 330 340 350
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT
360 370 380 390 400
KAEDRGMLLK TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP
410 420 430 440 450
HQDLQAQDRA HRIGQQNEVR VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ
460 470 480 490 500
AGMFDQKSSS HERRAFLQAI LEHEEQDESR HCSTGSGSAS FAHTAPPPAG
510 520 530 540 550
VNPDLEEPPL KEEDEVPDDE TVNQMIARHE EEFDLFMRMD LDRRREEARN
560 570 580 590 600
PKRKPRLMEE DELPSWIIKD DAEVERLTCE EEEEKMFGRG SRHRKEVDYS
610 620 630 640 650
DSLTEKQWLK AIEEGTLEEI EEEVRQKKSS RKRKRDSDAG SSTPTTSTRS
660 670 680 690 700
RDKDDESKKQ KKRGRPPAEK LSPNPPNLTK KMKKIVDAVI KYKDSSSGRQ
710 720 730 740 750
LSEVFIQLPS RKELPEYYEL IRKPVDFKKI KERIRNHKYR SLNDLEKDVM
760 770 780 790 800
LLCQNAQTFN LEGSLIYEDS IVLQSVFTSV RQKIEKEDDS EGEESEEEEE
810 820 830 840 850
GEEEGSESES RSVKVKIKLG RKEKAQDRLK GGRRRPSRGS RAKPVVSDDD
860
SEEEQEEDRS GSGSEED
Length:867
Mass (Da):100,153
Last modified:September 23, 2008 - v1
Checksum:i4E0298E6F27F051F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK299761 mRNA. Translation: BAG61650.1.
UniGeneiHs.327527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK299761 mRNA. Translation: BAG61650.1 .
UniGenei Hs.327527.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B4DSI8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG056636.

Miscellaneous databases

NextBioi 35474677.

Gene expression databases

Bgeei B4DSI8.
ExpressionAtlasi B4DSI8. baseline and differential.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
3.40.50.300. 2 hits.
InterProi IPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR029295. SnAC.
IPR000330. SNF2_N.
[Graphical view ]
Pfami PF00439. Bromodomain. 1 hit.
PF00271. Helicase_C. 1 hit.
PF14619. SnAC. 1 hit.
PF00176. SNF2_N. 1 hit.
[Graphical view ]
PRINTSi PR00503. BROMODOMAIN.
SMARTi SM00297. BROMO. 1 hit.
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view ]
SUPFAMi SSF47370. SSF47370. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEi PS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB4DSI8_HUMAN
AccessioniPrimary (citable) accession number: B4DSI8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.