B4DSB9 (B4DSB9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ51069, highly similar to DNA mismatch repair protein Msh2 EMBL BAG61581.1
Organism	Homo sapiens (Human) EMBL BAG61581.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	720 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	mismatch repair Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro mismatched DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DSB9 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 9354D1F3F157B864	FASTA	720	81,335
	10 20 30 40 50 60 MIGIWHIRLL LAISLSLKTF SLVTMICQLP LVLWVLKCPQ LMARDMGKLR QIIQRGGILI 70 80 90 100 110 120 TERKKADFST KDIYQDLNRL LKGKKGEQMN SAVLPEMENQ GSVEDTTGSQ SLAALLNKCK 130 140 150 160 170 180 TPQGQRLVNQ WIKQPLMDKN RIEERLNLVE AFVEDAELRQ TLQEDLLRRF PDLNRLAKKF 190 200 210 220 230 240 QRQAANLQDC YRLYQGINQL PNVIQALEKH EGKHQKLLLA VFVTPLTDLR SDFSKFQEMI 250 260 270 280 290 300 ETTLDMDQVE NHEFLVKPSF DPNLSELREI MNDLEKKMQS TLISAARDLG LDPGKQIKLD 310 320 330 340 350 360 SSAQFGYYFR VTCKEEKVLR NNKNFSTVDI QKNGVKFTNS KLTSLNEEYT KNKTEYEEAQ 370 380 390 400 410 420 DAIVKEIVNI SSGYVEPMQT LNDVLAQLDA VVSFAHVSNG APVPYVRPAI LEKGQGRIIL 430 440 450 460 470 480 KASRHACVEV QDEIAFIPND VYFEKDKQMF HIITGPNMGG KSTYIRQTGV IVLMAQIGCF 490 500 510 520 530 540 VPCESAEVSI VDCILARVGA GDSQLKGVST FMAEMLETAS ILRSATKDSL IIIDELGRGT 550 560 570 580 590 600 STYDGFGLAW AISEYIATKI GAFCMFATHF HELTALANQI PTVNNLHVTA LTTEETLTML 610 620 630 640 650 660 YQVKKGVCDQ SFGIHVAELA NFPKHVIECA KQKALELEEF QYIGESQGYD IMEPAAKKCY 670 680 690 700 710 720 LEREQGEKII QEFLSKVKQM PFTEMSEENI TIKLKQLKAE VIAKNNSFVN EIISRIKVTT

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAG61581.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK299667 mRNA. Translation: BAG61581.1.
IPI	IPI00942143.
UniGene	Hs.597656.
3D structure databases
ProteinModelPortal	B4DSB9.
SMR	B4DSB9. Positions 43-716.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000196498.
HOVERGEN	HBG006399.
Family and domain databases
InterPro	IPR000432. DNA_mismatch_repair_MutS_C. IPR007861. DNA_mismatch_repair_MutS_clamp. IPR007696. DNA_mismatch_repair_MutS_core. [Graphical view]
Pfam	PF05192. MutS_III. 1 hit. PF05190. MutS_IV. 1 hit. PF00488. MutS_V. 1 hit. [Graphical view]
SMART	SM00534. MUTSac. 1 hit. SM00533. MUTSd. 1 hit. [Graphical view]
SUPFAM	SSF48334. DNA_repair_MutS_domIII. 1 hit.
PROSITE	PS00486. DNA_MISMATCH_REPAIR_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35474619.

Entry information

Entry name

B4DSB9_HUMAN

Accession

Primary (citable) accession number: B4DSB9
Secondary accession number(s): E9PCH9

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.