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Protein
Submitted name:

cDNA FLJ51069, highly similar to DNA mismatch repair protein Msh2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51069, highly similar to DNA mismatch repair protein Msh2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiB4DSB9.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000233146.

Structurei

3D structure databases

ProteinModelPortaliB4DSB9.
SMRiB4DSB9. Positions 43-716.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000196498.
HOVERGENiHBG006399.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR011184. DNA_mismatch_repair_MutS.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
PIRSFiPIRSF005813. MSH2. 1 hit.
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DSB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGIWHIRLL LAISLSLKTF SLVTMICQLP LVLWVLKCPQ LMARDMGKLR
60 70 80 90 100
QIIQRGGILI TERKKADFST KDIYQDLNRL LKGKKGEQMN SAVLPEMENQ
110 120 130 140 150
GSVEDTTGSQ SLAALLNKCK TPQGQRLVNQ WIKQPLMDKN RIEERLNLVE
160 170 180 190 200
AFVEDAELRQ TLQEDLLRRF PDLNRLAKKF QRQAANLQDC YRLYQGINQL
210 220 230 240 250
PNVIQALEKH EGKHQKLLLA VFVTPLTDLR SDFSKFQEMI ETTLDMDQVE
260 270 280 290 300
NHEFLVKPSF DPNLSELREI MNDLEKKMQS TLISAARDLG LDPGKQIKLD
310 320 330 340 350
SSAQFGYYFR VTCKEEKVLR NNKNFSTVDI QKNGVKFTNS KLTSLNEEYT
360 370 380 390 400
KNKTEYEEAQ DAIVKEIVNI SSGYVEPMQT LNDVLAQLDA VVSFAHVSNG
410 420 430 440 450
APVPYVRPAI LEKGQGRIIL KASRHACVEV QDEIAFIPND VYFEKDKQMF
460 470 480 490 500
HIITGPNMGG KSTYIRQTGV IVLMAQIGCF VPCESAEVSI VDCILARVGA
510 520 530 540 550
GDSQLKGVST FMAEMLETAS ILRSATKDSL IIIDELGRGT STYDGFGLAW
560 570 580 590 600
AISEYIATKI GAFCMFATHF HELTALANQI PTVNNLHVTA LTTEETLTML
610 620 630 640 650
YQVKKGVCDQ SFGIHVAELA NFPKHVIECA KQKALELEEF QYIGESQGYD
660 670 680 690 700
IMEPAAKKCY LEREQGEKII QEFLSKVKQM PFTEMSEENI TIKLKQLKAE
710 720
VIAKNNSFVN EIISRIKVTT
Length:720
Mass (Da):81,335
Last modified:September 23, 2008 - v1
Checksum:i9354D1F3F157B864
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK299667 mRNA. Translation: BAG61581.1.
UniGeneiHs.597656.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK299667 mRNA. Translation: BAG61581.1.
UniGeneiHs.597656.

3D structure databases

ProteinModelPortaliB4DSB9.
SMRiB4DSB9. Positions 43-716.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000233146.

Proteomic databases

PRIDEiB4DSB9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000196498.
HOVERGENiHBG006399.

Miscellaneous databases

NextBioi35474619.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR011184. DNA_mismatch_repair_MutS.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
PIRSFiPIRSF005813. MSH2. 1 hit.
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB4DSB9_HUMAN
AccessioniPrimary (citable) accession number: B4DSB9
Secondary accession number(s): E9PCH9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 24, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.