B4DS76 (B4DS76_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mitogen-activated protein kinase kinase kinase 11 Ensembl ENSP00000433886

Submitted name:
cDNA FLJ53177, highly similar to Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) EMBL BAG61538.1
Submitted name:
cDNA, FLJ78931, highly similar to Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) EMBL BAH14403.1

Gene names

Name:

MAP3K11 Ensembl ENSP00000433886

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAG61538.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	590 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Kinase EMBL BAG61538.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell death Inferred from electronic annotation. Source: Compara positive regulation of neuron apoptotic process Inferred from electronic annotation. Source: Compara protein autophosphorylation Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: Compara JUN kinase kinase kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DS76 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: C7C24CA0C053133D	FASTA	590	65,344
	10 20 30 40 50 60 MEHKTLKITD FGLAREWHKT TQMSAAGTYA WMAPEVIKAS TFSKGSDVWS FGVLLWELLT 70 80 90 100 110 120 GEVPYRGIDC LAVAYGVAVN KLTLPIPSTC PEPFAQLMAD CWAQDPHRRP DFASILQQLE 130 140 150 160 170 180 ALEAQVLREM PRDSFHSMQE GWKREIQGLF DELRAKEKEL LSREEELTRA AREQRSQAEQ 190 200 210 220 230 240 LRRREHLLAQ WELEVFEREL TLLLQQVDRE RPHVRRRRGT FKRSKLRARD GGERISMPLD 250 260 270 280 290 300 FKHRITVQAS PGLDRRRNVF EVGPGDSPTF PRFRAIQLEP AEPGQAWGRQ SPRRLEDSSN 310 320 330 340 350 360 GERRACWAWG PSSPKPGEAQ NGRRRSRMDE ATWYLDSDDS SPLGSPSTPP ALNGNPPRPS 370 380 390 400 410 420 LEPEEPKRPV PAERGSSSGT PKLIQRALLR GTALLASLGL GRDLQPPGGP GRERGESPTT 430 440 450 460 470 480 PPTPTPAPCP TEPPPSPLIC FSLKTPDSPP TPAPLLLDLG IPVGQRSAKS PRREEEPRGG 490 500 510 520 530 540 TVSPPPGTSR SAPGTPGTPR SPPLGLISRP RPSPLRSRID PWSFVSAGPR PSPLPSPQPA 550 560 570 580 590 PRRAPWTLFP DSDPFWDSPP ANPFQGGPQD CRAQTKDMGA QAPWVPEAGP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAG61538.1.
[3]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Caudate nucleus EMBL BAH14403.1.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP001362 Genomic DNA. No translation available. AK299609 mRNA. Translation: BAG61538.1. AK316032 mRNA. Translation: BAH14403.1.
IPI	IPI00976246.
UniGene	Hs.502872.
3D structure databases
SMR	B4DS76. Positions 1-211.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000530153; ENSP00000433886; ENSG00000173327.
Organism-specific databases
HGNC	HGNC:6850. MAP3K11.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG067662.
Gene expression databases
ArrayExpress	B4DS76.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR015785. MAPKKK9/10/11-like. IPR000719. Prot_kinase_cat_dom. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. [Graphical view]
PANTHER	PTHR23257:SF87. PTHR23257:SF87. 1 hit.
Pfam	PF07714. Pkinase_Tyr. 1 hit. [Graphical view]
PRINTS	PR00109. TYRKINASE.
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35474584.

Entry information

Entry name

B4DS76_HUMAN

Accession

Primary (citable) accession number: B4DS76

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.