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Protein
Submitted name:

Very-long-chain enoyl-CoA reductase

Gene

TECR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Very-long-chain enoyl-CoA reductaseImported
Submitted name:
cDNA FLJ58248, highly similar to Synaptic glycoprotein SC2Imported
Gene namesi
Name:TECRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000099797.11.
HGNCiHGNC:4551. TECR.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 29HelicalSequence analysisAdd BLAST18
Transmembranei41 – 60HelicalSequence analysisAdd BLAST20
Transmembranei101 – 126HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000099797.

PTM / Processingi

Proteomic databases

MaxQBiB4DR74.

Expressioni

Gene expression databases

BgeeiENSG00000099797.
ExpressionAtlasiB4DR74. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 128S5A_REDUCTASEInterPro annotationAdd BLAST87

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1639. Eukaryota.
ENOG410XR2S. LUCA.
GeneTreeiENSGT00510000046645.
HOVERGENiHBG084448.

Family and domain databases

InterProiView protein in InterPro
IPR001104. 3-oxo-5_a-steroid_4-DH_C.
PfamiView protein in Pfam
PF02544. Steroid_dh. 1 hit.
PROSITEiView protein in PROSITE
PS50244. S5A_REDUCTASE. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DR74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLRNIFKNC TYYWGFAAWM AYYINHPLYT PPTYGAQQVK LALAIFVICQ
60 70 80 90 100
LGNFSIHMAL RDLRPAGSKT RKIPYPTKNP FTWLFLLVSC PNYTYEVGSW
110 120 130 140 150
IGFAIMTQCL PVALFSLVGF TQMTIWAKGK HRSYLKEFRD YPPLRMPIIP

FLL
Length:153
Mass (Da):17,801
Last modified:September 23, 2008 - v1
Checksum:i580EED3A326E2510
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009004 Genomic DNA. No translation available.
AC010527 Genomic DNA. No translation available.
AC012318 Genomic DNA. No translation available.
AC024585 Genomic DNA. No translation available.
AK299134 mRNA. Translation: BAG61186.1.
UniGeneiHs.515642.

Genome annotation databases

EnsembliENST00000596073; ENSP00000472697; ENSG00000099797.
ENST00000600083; ENSP00000472114; ENSG00000099797.
UCSCiuc002mzc.4. human.

Similar proteinsi

Entry informationi

Entry nameiB4DR74_HUMAN
AccessioniPrimary (citable) accession number: B4DR74
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 27, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported