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Protein
Submitted name:

cDNA FLJ59376, highly similar to Mus musculus SH2B adaptor protein 1 (Sh2b1), mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiB4DQ00.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ59376, highly similar to Mus musculus SH2B adaptor protein 1 (Sh2b1), mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiB4DQ00.
PeptideAtlasiB4DQ00.

Structurei

3D structure databases

ProteinModelPortaliB4DQ00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini217 – 315SH2InterPro annotationAdd BLAST99

Keywords - Domaini

SH2 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IMWK. Eukaryota.
ENOG41102PH. LUCA.
HOGENOMiHOG000047355.
HOVERGENiHBG103068.

Family and domain databases

CDDicd10346. SH2_SH2B_family. 1 hit.
Gene3Di2.30.29.30. 1 hit.
3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000980. SH2.
IPR030523. SH2B.
IPR030521. SH2B1.
IPR035057. SH2B1_SH2.
PANTHERiPTHR10872. PTHR10872. 1 hit.
PTHR10872:SF8. PTHR10872:SF8. 1 hit.
PfamiView protein in Pfam
PF00169. PH. 1 hit.
PF00017. SH2. 1 hit.
PRINTSiPR00401. SH2DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 1 hit.
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiView protein in PROSITE
PS50001. SH2. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DQ00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEASRPRLS IPCSSITDVR TTTALEMPDR ENTFVVKVEG PSEYIMETVD
60 70 80 90 100
AQHVKAWVSD IQECLSPGPC PATSPRPMTL PLAPGTSFLT RENTDSLELS
110 120 130 140 150
CLNHSESLPS QDLLLGPSES NDLLSQGAYG GLSDRPSASI SPSSASIAAS
160 170 180 190 200
HFDSMELLPP ELPPRIPIEE GPPTGTVHPL SAPYPPLDTP ETATGSFLFQ
210 220 230 240 250
GEPEGGEGDQ PLSGYPWFHG MLSRLKAAQL VLTGGTGSHG VFLVRQSETR
260 270 280 290 300
RGEYVLTFNF QGKAKHLRLS LNEEGQCRVQ HLWFQSIFDM LEHFRVHPIP
310 320 330 340 350
LESGGSSDVV LVSYVPSSQR QQGEQSRSAG EEVPVHPRSE AGSRLGAMRG
360 370
CAREMDATPM PPAPSCPSER VTV
Length:373
Mass (Da):40,250
Last modified:September 23, 2008 - v1
Checksum:i3A3E2A72A15F6F97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK298569 mRNA. Translation: BAG60762.1.
UniGeneiHs.15744.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB4DQ00_HUMAN
AccessioniPrimary (citable) accession number: B4DQ00
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 5, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.