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Protein
Submitted name:

cDNA FLJ56412, highly similar to Advanced glycosylation end product-specific receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56412, highly similar to Advanced glycosylation end product-specific receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei372 – 394HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiB4DNX3.
PRIDEiB4DNX3.

Expressioni

Gene expression databases

BgeeiENSG00000204305.
GenevisibleiB4DNX3. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000364217.

Structurei

3D structure databases

ProteinModelPortaliB4DNX3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 147Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST86
Domaini155 – 252Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST98
Domaini258 – 348Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST91

Keywords - Domaini

Immunoglobulin domainSAAS annotation, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IVT2. Eukaryota.
ENOG4111C4I. LUCA.
HOGENOMiHOG000232122.
HOVERGENiHBG004350.
KOiK19722.
PhylomeDBiB4DNX3.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiIPR013162. CD80_C2-set.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013151. Immunoglobulin.
[Graphical view]
PfamiPF08205. C2-set_2. 1 hit.
PF00047. ig. 1 hit.
PF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
PROSITEiPS50835. IG_LIKE. 3 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DNX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAGERVQAP PRAEATAGRG ADRARTLEGS RMAAGTAVGA WVLVLSLWGA
60 70 80 90 100
VVGAQNITAR IGEPLVLKCK GAPKKPPQRL EWKLNTGRTE AWKVLSPQGG
110 120 130 140 150
GPWDSVARVL PNGSLFLPAV GIQDEGIFRC QAMNRNGKET KSNYRVRVYQ
160 170 180 190 200
IPGKPEIVDS ASELTAGVPN KVGTCVSEGS YPAGTLSWHL DGKPLVPNEK
210 220 230 240 250
GVSVKEQTRR HPETGLFTLQ SELMVTPARG GDPRPTFSCS FSPGLPRHRA
260 270 280 290 300
LRTAPIQPRV WEPVPLEEVQ LVVEPEGGAV APGGTVTLTC EVPAQPSPQI
310 320 330 340 350
HWMKDGVPLP LPPSPVLILP EIGPQDQGTY SCVATHSSHG PQESRAVSIS
360 370 380 390 400
IIEPGEEGPT AGSVGGSGLG TLALALGILG GLGTAALLIG VILWQRRQRR
410 420 430
GEERKAPENQ EEEEERAELN QSEEPEAGES STGGP
Length:435
Mass (Da):45,980
Last modified:September 23, 2008 - v1
Checksum:i6FF01FC403107051
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK298100 mRNA. Translation: BAG60385.1.
RefSeqiNP_001127.1. NM_001136.4.
NP_001193858.1. NM_001206929.1.
NP_001193861.1. NM_001206932.1.
NP_001193863.1. NM_001206934.1.
NP_001193865.1. NM_001206936.1.
NP_001193869.1. NM_001206940.1.
NP_001193883.1. NM_001206954.1.
NP_001193895.1. NM_001206966.1.
NP_751947.1. NM_172197.2.
UniGeneiHs.534342.

Genome annotation databases

GeneIDi177.
KEGGihsa:177.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK298100 mRNA. Translation: BAG60385.1.
RefSeqiNP_001127.1. NM_001136.4.
NP_001193858.1. NM_001206929.1.
NP_001193861.1. NM_001206932.1.
NP_001193863.1. NM_001206934.1.
NP_001193865.1. NM_001206936.1.
NP_001193869.1. NM_001206940.1.
NP_001193883.1. NM_001206954.1.
NP_001193895.1. NM_001206966.1.
NP_751947.1. NM_172197.2.
UniGeneiHs.534342.

3D structure databases

ProteinModelPortaliB4DNX3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000364217.

Proteomic databases

PaxDbiB4DNX3.
PRIDEiB4DNX3.

Protocols and materials databases

DNASUi177.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi177.
KEGGihsa:177.

Organism-specific databases

CTDi177.

Phylogenomic databases

eggNOGiENOG410IVT2. Eukaryota.
ENOG4111C4I. LUCA.
HOGENOMiHOG000232122.
HOVERGENiHBG004350.
KOiK19722.
PhylomeDBiB4DNX3.

Miscellaneous databases

ChiTaRSiAGER. human.
GenomeRNAii177.

Gene expression databases

BgeeiENSG00000204305.
GenevisibleiB4DNX3. HS.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiIPR013162. CD80_C2-set.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013151. Immunoglobulin.
[Graphical view]
PfamiPF08205. C2-set_2. 1 hit.
PF00047. ig. 1 hit.
PF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
PROSITEiPS50835. IG_LIKE. 3 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DNX3_HUMAN
AccessioniPrimary (citable) accession number: B4DNX3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 5, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.