B4DNT6 (B4DNT6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ53631, highly similar to Intercellular adhesion molecule 1 EMBL BAG60348.1
Organism	Homo sapiens (Human) EMBL BAG60348.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	442 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	T cell antigen processing and presentation Inferred from electronic annotation. Source: Compara cell adhesion mediated by integrin Inferred from electronic annotation. Source: Compara cell aging Inferred from electronic annotation. Source: Compara cellular response to alkaloid Inferred from electronic annotation. Source: Compara cellular response to glucose stimulus Inferred from electronic annotation. Source: Compara cellular response to hypoxia Inferred from electronic annotation. Source: Compara cellular response to interleukin-1 Inferred from electronic annotation. Source: Compara cellular response to lipopolysaccharide Inferred from electronic annotation. Source: Compara cellular response to nutrient levels Inferred from electronic annotation. Source: Compara cellular response to tumor necrosis factor Inferred from electronic annotation. Source: Compara leukocyte cell-cell adhesion Inferred from electronic annotation. Source: Compara negative regulation of calcium ion transport Inferred from electronic annotation. Source: Compara ovarian follicle development Inferred from electronic annotation. Source: Compara positive regulation of NF-kappaB transcription factor activity Inferred from electronic annotation. Source: Compara positive regulation of nitric oxide biosynthetic process Inferred from electronic annotation. Source: Compara positive regulation of vasoconstriction Inferred from electronic annotation. Source: Compara regulation of cell adhesion Inferred from electronic annotation. Source: Compara regulation of cell shape Inferred from electronic annotation. Source: Compara response to amino acid stimulus Inferred from electronic annotation. Source: Compara response to amphetamine Inferred from electronic annotation. Source: Compara response to copper ion Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara response to ethanol Inferred from electronic annotation. Source: Compara response to gonadotropin stimulus Inferred from electronic annotation. Source: Compara response to ionizing radiation Inferred from electronic annotation. Source: Compara response to organic cyclic compound Inferred from electronic annotation. Source: Compara response to sulfur dioxide Inferred from electronic annotation. Source: Compara
Cellular_component	external side of plasma membrane Inferred from electronic annotation. Source: Compara extracellular space Inferred from electronic annotation. Source: Compara immunological synapse Inferred from electronic annotation. Source: Compara
Molecular_function	cell surface binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DNT6 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 13D0642E94C25477	FASTA	442	48,442
	10 20 30 40 50 60 MCYSNCPDGQ STAKTFLTVY WTPERVELAP LPSWQPVGKN LTLRCQVEGG APRANLTVVL 70 80 90 100 110 120 LRGEKELKRE PAVGEPAEVT TTVLVRRDHH GANFSCRTEL DLRPQGLELF ENTSAPYQLQ 130 140 150 160 170 180 TFVLPATPPQ LVSPRVLEVD TQGTVVCSLD GLFPVSEAQV HLALGDQRLN PTVTYGNDSF 190 200 210 220 230 240 SAKASVSVTA EDEGTQRLTC AVILGNQSQE TLQTVTIYSF PAPNVILTKP EVSEGTEVTV 250 260 270 280 290 300 KCEAHPRAKV TLNGVPAQPL GPRAQLLLKA TPEDNGRSFS CSATLEVAGQ LIHKNQTREL 310 320 330 340 350 360 RVLYGPRLDE RDCPGNWTWP ENSQQTPMCQ AWGNPLPELK CLKDGTFPLP IGESVTVTRD 370 380 390 400 410 420 LEGTYLCRAR STQGEVTRKV TVNVLSPRYE IVIITVVAAA VIMGTAGLST YLYNRQRKIK 430 440 KYRLQQAQKG TPMKPNTQAT PP

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Lung EMBL BAG60348.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK298054 mRNA. Translation: BAG60348.1.
IPI	IPI00008494.
UniGene	Hs.643447.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4DNT6.
Proteomic databases
PRIDE	B4DNT6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG052074.
Gene expression databases
ArrayExpress	B4DNT6.
Bgee	B4DNT6.
Family and domain databases
Gene3D	2.60.40.10. 4 hits.
InterPro	IPR003988. ICAM. IPR013768. ICAM_N. IPR003987. ICAM_VCAM_N. IPR013783. Ig-like_fold. IPR003599. Ig_sub. [Graphical view]
Pfam	PF03921. ICAM_N. 1 hit. [Graphical view]
PRINTS	PR01473. ICAM. PR01472. ICAMVCAM1.
SMART	SM00409. IG. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	B4DNT6.
NextBio	35473698.

Entry information

Entry name

B4DNT6_HUMAN

Accession

Primary (citable) accession number: B4DNT6

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.