B4DMX8 (B4DMX8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ52697, highly similar to Gamma-secretase subunit APH-1A EMBL BAG60040.1
Organism	Homo sapiens (Human) EMBL BAG60040.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	131 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	positive regulation of catalytic activity Inferred from electronic annotation. Source: InterPro protein processing Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DMX8 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: AF5D254A78114A16	FASTA	131	14,183
	10 20 30 40 50 60 MAYVSGLSFG IISGVFSVIN ILADALGPGV VGIHGDSPYY FLTSAFLTAA IILLHTFWGV 70 80 90 100 110 120 VFFDACERRR YWALGLVVGS HLLTSGLTFL NPWYEASLLP IYAVTVSMGL WAFITAGGSL 130 RSIQRSLLCK D

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Kidney EMBL BAG60040.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK297680 mRNA. Translation: BAG60040.1.
IPI	IPI00844196.
UniGene	Hs.108408. Hs.735911.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4DMX8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc010pbz.2. human.
Phylogenomic databases
HOVERGEN	HBG050541.
Gene expression databases
ArrayExpress	B4DMX8.
Bgee	B4DMX8.
Family and domain databases
InterPro	IPR009294. Aph-1. [Graphical view]
PANTHER	PTHR12889. PTHR12889. 1 hit.
Pfam	PF06105. Aph-1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35473455.

Entry information

Entry name

B4DMX8_HUMAN

Accession

Primary (citable) accession number: B4DMX8

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.