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Protein
Submitted name:

cDNA FLJ52697, highly similar to Gamma-secretase subunit APH-1A

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52697, highly similar to Gamma-secretase subunit APH-1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Transmembranei39 – 64HelicalSequence analysisAdd BLAST26
Transmembranei71 – 93HelicalSequence analysisAdd BLAST23
Transmembranei99 – 120HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DMX8

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3972 Eukaryota
ENOG4111FIJ LUCA
HOVERGENiHBG050541

Family and domain databases

InterProiView protein in InterPro
IPR009294 Aph-1
PANTHERiPTHR12889 PTHR12889, 1 hit
PfamiView protein in Pfam
PF06105 Aph-1, 1 hit

Sequencei

Sequence statusi: Complete.

B4DMX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYVSGLSFG IISGVFSVIN ILADALGPGV VGIHGDSPYY FLTSAFLTAA
60 70 80 90 100
IILLHTFWGV VFFDACERRR YWALGLVVGS HLLTSGLTFL NPWYEASLLP
110 120 130
IYAVTVSMGL WAFITAGGSL RSIQRSLLCK D
Length:131
Mass (Da):14,183
Last modified:September 23, 2008 - v1
Checksum:iAF5D254A78114A16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK297680 mRNA Translation: BAG60040.1
UniGeneiHs.108408
Hs.735911

Similar proteinsi

Entry informationi

Entry nameiB4DMX8_HUMAN
AccessioniPrimary (citable) accession number: B4DMX8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 31, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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