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Protein
Submitted name:

cDNA FLJ52697, highly similar to Gamma-secretase subunit APH-1A

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. positive regulation of catalytic activity Source: InterPro
  2. protein processing Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52697, highly similar to Gamma-secretase subunit APH-1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB4DMX8.
ExpressionAtlasiB4DMX8. baseline and differential.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG050541.

Family and domain databases

InterProiIPR009294. Aph-1.
[Graphical view]
PANTHERiPTHR12889. PTHR12889. 1 hit.
PfamiPF06105. Aph-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DMX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYVSGLSFG IISGVFSVIN ILADALGPGV VGIHGDSPYY FLTSAFLTAA
60 70 80 90 100
IILLHTFWGV VFFDACERRR YWALGLVVGS HLLTSGLTFL NPWYEASLLP
110 120 130
IYAVTVSMGL WAFITAGGSL RSIQRSLLCK D
Length:131
Mass (Da):14,183
Last modified:September 22, 2008 - v1
Checksum:iAF5D254A78114A16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK297680 mRNA. Translation: BAG60040.1.
UniGeneiHs.108408.
Hs.735911.

Genome annotation databases

UCSCiuc010pbz.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK297680 mRNA. Translation: BAG60040.1.
UniGeneiHs.108408.
Hs.735911.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc010pbz.2. human.

Phylogenomic databases

HOVERGENiHBG050541.

Miscellaneous databases

NextBioi35473455.

Gene expression databases

BgeeiB4DMX8.
ExpressionAtlasiB4DMX8. baseline and differential.

Family and domain databases

InterProiIPR009294. Aph-1.
[Graphical view]
PANTHERiPTHR12889. PTHR12889. 1 hit.
PfamiPF06105. Aph-1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported.

Entry informationi

Entry nameiB4DMX8_HUMAN
AccessioniPrimary (citable) accession number: B4DMX8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2008
Last sequence update: September 22, 2008
Last modified: October 28, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.