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B4DMV8

- B4DMV8_HUMAN

UniProt

B4DMV8 - B4DMV8_HUMAN

Protein

Glucosylceramidase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.UniRule annotation

    GO - Molecular functioni

    1. glucosylceramidase activity Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. sphingolipid metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseUniRule annotation, Hydrolase

    Keywords - Biological processi

    Lipid metabolism, Sphingolipid metabolismUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlucosylceramidaseUniRule annotation (EC:3.2.1.45UniRule annotation)
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Pathology & Biotechi

    Protein family/group databases

    Allergomei8244. Hom s Glucocerebrosidase.

    PTM / Processingi

    Proteomic databases

    PRIDEiB4DMV8.

    Structurei

    3D structure databases

    ProteinModelPortaliB4DMV8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 30 family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG002285.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001139. Glyco_hydro_30.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR11069. PTHR11069. 1 hit.
    PfamiPF02055. Glyco_hydro_30. 1 hit.
    [Graphical view]
    PRINTSiPR00843. GLHYDRLASE30.
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4DMV8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MCLQPLQEQK QWALDGAEYR TIQANCTGTG IGYNTIWVPM ASCDFSIRTY    50
    TYADTPDDFQ LHNFSLPEED TKLKIPLIHR ALQLAQRPVS LLASPWTSPT 100
    RLKTKGAGNG KGPLKGQPRD IYHQTWARYI VKFLDAYAEH KLQFWAVTAE 150
    NEPSAGLLSG YPFQCLGFTP EHQRDFIARD LGPTLANGAH HNVRPLMLDD 200
    QRLLLPHWAK VVLTDPEAAK YVHGIAVHWY LDFLAPAKAT LRETHHLFPN 250
    TMLFASEACV GSKFWEQSVR LGSWDRGMQY SHSIITNLLY HVVGWTDWNP 300
    SL 302
    Length:302
    Mass (Da):34,299
    Last modified:September 23, 2008 - v1
    Checksum:i144F45CA39C0C658
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK297653 mRNA. Translation: BAG60020.1.
    UniGeneiHs.719930.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK297653 mRNA. Translation: BAG60020.1 .
    UniGenei Hs.719930.

    3D structure databases

    ProteinModelPortali B4DMV8.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 8244. Hom s Glucocerebrosidase.

    Proteomic databases

    PRIDEi B4DMV8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG002285.

    Miscellaneous databases

    NextBioi 35473437.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001139. Glyco_hydro_30.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR11069. PTHR11069. 1 hit.
    Pfami PF02055. Glyco_hydro_30. 1 hit.
    [Graphical view ]
    PRINTSi PR00843. GLHYDRLASE30.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiB4DMV8_HUMAN
    AccessioniPrimary (citable) accession number: B4DMV8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.