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B4DME2

- B4DME2_HUMAN

UniProt

B4DME2 - B4DME2_HUMAN

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Protein
Submitted name:

Protein phosphatase 1 regulatory subunit 12C

Gene

PPP1R12C

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Protein phosphatase 1 regulatory subunit 12CImported
Submitted name:
cDNA FLJ59720, highly similar to Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 12C (PPP1R12C), mRNAImported
Gene namesi
Name:PPP1R12CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:14947. PPP1R12C.

Expressioni

Gene expression databases

ExpressionAtlasiB4DME2. baseline.

Structurei

3D structure databases

ProteinModelPortaliB4DME2.
SMRiB4DME2. Positions 18-241, 453-504.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 4 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation, RepeatUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119141.
HOGENOMiHOG000290648.
HOVERGENiHBG104929.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 4 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DME2 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRNGGPCQPL AAGPRAEGAS VNWSVTAWGP GTQACIDENL EVVRFLVEQG
60 70 80 90 100
ATVNQADNEG WTPLHVAASC GYLDIARYLL SHGANIAAVN SDGDLPLDLA
110 120 130 140 150
ESDAMEGLLK AEIARRGVDV EAAKRAEEEL LLHDTRCWLN GGAMPEARHP
160 170 180 190 200
RTGASALHVA AAKGYIEVMR LLLQAGYDPE LRDGDGWTPL HAAAHWGVED
210 220 230 240 250
ACRLLAEHGG GMDSLTHAGQ RPCDLADEEV LSLLEELARK QEDLRNQKEA
260 270 280 290 300
SQSRGQEPQA PSSSKHRRSS VCRLSSREKI SLQDLSKERR PGGAGGPPIQ
310 320 330 340 350
DEDEGEEGPT EPPPAEPRTL NGVSSPPHPS PKSPVQLEEA PFSRRFGLLK
360 370 380 390 400
TGSSGALGPP ERRTAEGAPG AGLQRSASSS WLEGTSTQAK ELRLARITPT
410 420 430 440 450
PSPKLPEPSV LSEVTKPPPC LENSSPPSRI PEPESPAKPN VPTASTAPPA
460 470 480 490 500
DSRDRRRSYQ MPVRDEESES QRKARSRLMR QSRRSTQGVT LTDLKEAEKA
510 520 530 540 550
AGKAPESEKP AQSLDPSRRP RVPGVENSDS PAQREAPDGQ GPGPQAAREH
560 570 580 590 600
RKVGKEWRGP AEGEEAEPAD RSQESSTLEG GPSARRQRWQ RDLNPEPEPE
610 620 630 640 650
SEEPDGGFRT LYAELRRENE RLREALTETT LRLAQLKVEL ERATQRQERF
660 670 680 690 700
AERPALLELE RFERRALERK AAELEEELKA LSDLRADNQR LKDENAALIR

VISKLSK
Length:707
Mass (Da):77,169
Last modified:September 23, 2008 - v1
Checksum:i991C11608AB2807F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005782 Genomic DNA. No translation available.
AC010327 Genomic DNA. No translation available.
AK297426 mRNA. Translation: BAG59854.1.
UniGeneiHs.631579.

Genome annotation databases

EnsembliENST00000435544; ENSP00000387833; ENSG00000125503.
UCSCiuc010yfs.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005782 Genomic DNA. No translation available.
AC010327 Genomic DNA. No translation available.
AK297426 mRNA. Translation: BAG59854.1 .
UniGenei Hs.631579.

3D structure databases

ProteinModelPortali B4DME2.
SMRi B4DME2. Positions 18-241, 453-504.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000435544 ; ENSP00000387833 ; ENSG00000125503 .
UCSCi uc010yfs.2. human.

Organism-specific databases

HGNCi HGNC:14947. PPP1R12C.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000119141.
HOGENOMi HOG000290648.
HOVERGENi HBG104929.

Miscellaneous databases

NextBioi 35473299.

Gene expression databases

ExpressionAtlasi B4DME2. baseline.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view ]
Pfami PF12796. Ank_2. 2 hits.
[Graphical view ]
PRINTSi PR01415. ANKYRIN.
SMARTi SM00248. ANK. 4 hits.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiB4DME2_HUMAN
AccessioniPrimary (citable) accession number: B4DME2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3