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B4DMC9

- B4DMC9_HUMAN

UniProt

B4DMC9 - B4DMC9_HUMAN

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Protein
Submitted name:

cDNA FLJ50990, highly similar to Gap junction alpha-1 protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. apoptotic process Source: Ensembl
  2. ATP transport Source: Ensembl
  3. cell-cell signaling Source: Ensembl
  4. cellular response to mechanical stimulus Source: Ensembl
  5. chronic inflammatory response Source: Ensembl
  6. endothelium development Source: Ensembl
  7. heart development Source: Ensembl
  8. negative regulation of cardiac muscle cell proliferation Source: Ensembl
  9. neuron projection morphogenesis Source: Ensembl
  10. positive regulation of behavioral fear response Source: Ensembl
  11. positive regulation of cell communication by chemical coupling Source: Ensembl
  12. positive regulation of cytosolic calcium ion concentration Source: Ensembl
  13. positive regulation of glomerular filtration Source: Ensembl
  14. positive regulation of protein catabolic process Source: Ensembl
  15. positive regulation of vasoconstriction Source: Ensembl
  16. positive regulation of vasodilation Source: Ensembl
  17. protein oligomerization Source: Ensembl
  18. regulation of calcium ion transport Source: Ensembl
  19. regulation of tight junction assembly Source: Ensembl
  20. response to fluid shear stress Source: Ensembl
  21. response to peptide hormone Source: Ensembl
  22. response to pH Source: Ensembl
  23. vascular transport Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50990, highly similar to Gap junction alpha-1 proteinImported
Submitted name:
cDNA, FLJ79058, highly similar to Gap junction alpha-1 proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. connexon complex Source: InterPro
  2. early endosome Source: Ensembl
  3. fascia adherens Source: Ensembl
  4. Golgi apparatus Source: Ensembl
  5. integral component of membrane Source: UniProtKB-KW
  6. lysosome Source: Ensembl
  7. membrane raft Source: Ensembl
  8. mitochondrial outer membrane Source: Ensembl
  9. multivesicular body Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotations, Gap junctionSAAS annotations, Membrane

Expressioni

Gene expression databases

ArrayExpressiB4DMC9.
BgeeiB4DMC9.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG009576.

Family and domain databases

InterProiIPR000500. Connexin.
IPR002261. Connexin43.
IPR013124. Connexin43_C.
IPR019570. Connexin_CCC.
IPR017990. Connexin_CS.
[Graphical view]
PANTHERiPTHR11984. PTHR11984. 1 hit.
PfamiPF03508. Connexin43. 1 hit.
PF10582. Connexin_CCC. 1 hit.
[Graphical view]
PRINTSiPR00206. CONNEXIN.
PR01132. CONNEXINA1.
SMARTiSM01089. Connexin_CCC. 1 hit.
[Graphical view]
PROSITEiPS00408. CONNEXINS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DMC9-1 [UniParc]FASTAAdd to Basket

« Hide

MRKEEKLNKK EEELKVAQTD GVNVDMHLKQ IEIKKFKYGI EEHGKVKMRG    50
GLLRTYIISI LFKSIFEVAF LLIQWYIYGF SLSAVYTCKR DPCPHQVDCF 100
LSRPTEKTIF IIFMLVVSLV SLALNIIELF YVFFKGVKDR VKGKSDPYHA 150
TSGALSPAKD CGSQKYAYFN GCSSPTAPLS PMSPPGYKLV TGDRNNSSCR 200
NYNKQASEQN WANYSAEQNR MGQAGSTISN SHAQPFDFPD DNQNSKKLAA 250
GHELQPLAIV DQRPSSRASS RASSRPRPDD LEI 283
Length:283
Mass (Da):31,864
Last modified:September 23, 2008 - v1
Checksum:i6C4B79EE24F63AA6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK297402 mRNA. Translation: BAG59841.1.
AK316159 mRNA. Translation: BAH14530.1.

Genome annotation databases

UCSCiuc011ebp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK297402 mRNA. Translation: BAG59841.1 .
AK316159 mRNA. Translation: BAH14530.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc011ebp.1. human.

Phylogenomic databases

HOVERGENi HBG009576.

Miscellaneous databases

NextBioi 35473288.

Gene expression databases

ArrayExpressi B4DMC9.
Bgeei B4DMC9.

Family and domain databases

InterProi IPR000500. Connexin.
IPR002261. Connexin43.
IPR013124. Connexin43_C.
IPR019570. Connexin_CCC.
IPR017990. Connexin_CS.
[Graphical view ]
PANTHERi PTHR11984. PTHR11984. 1 hit.
Pfami PF03508. Connexin43. 1 hit.
PF10582. Connexin_CCC. 1 hit.
[Graphical view ]
PRINTSi PR00206. CONNEXIN.
PR01132. CONNEXINA1.
SMARTi SM01089. Connexin_CCC. 1 hit.
[Graphical view ]
PROSITEi PS00408. CONNEXINS_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB4DMC9_HUMAN
AccessioniPrimary (citable) accession number: B4DMC9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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