Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B4DMC9

- B4DMC9_HUMAN

UniProt

B4DMC9 - B4DMC9_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

cDNA FLJ50990, highly similar to Gap junction alpha-1 protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. gap junction channel activity Source: Ensembl

GO - Biological processi

  1. adult heart development Source: Ensembl
  2. apoptotic process Source: Ensembl
  3. ATP transport Source: Ensembl
  4. atrial ventricular junction remodeling Source: Ensembl
  5. blood vessel morphogenesis Source: Ensembl
  6. cardiac conduction Source: Ensembl
  7. cell-cell junction organization Source: Ensembl
  8. cell-cell signaling Source: Ensembl
  9. cell communication by chemical coupling Source: Ensembl
  10. cell communication by electrical coupling Source: Ensembl
  11. cellular response to mechanical stimulus Source: Ensembl
  12. chronic inflammatory response Source: Ensembl
  13. embryonic digit morphogenesis Source: Ensembl
  14. endothelium development Source: Ensembl
  15. epithelial cell maturation Source: Ensembl
  16. heart looping Source: Ensembl
  17. in utero embryonic development Source: Ensembl
  18. lens development in camera-type eye Source: Ensembl
  19. milk ejection Source: Ensembl
  20. negative regulation of cardiac muscle cell proliferation Source: Ensembl
  21. negative regulation of gene expression Source: Ensembl
  22. neuron migration Source: Ensembl
  23. neuron projection morphogenesis Source: Ensembl
  24. osteoblast differentiation Source: Ensembl
  25. positive regulation of behavioral fear response Source: Ensembl
  26. positive regulation of cell communication by chemical coupling Source: Ensembl
  27. positive regulation of cytosolic calcium ion concentration Source: Ensembl
  28. positive regulation of gene expression Source: Ensembl
  29. positive regulation of glomerular filtration Source: Ensembl
  30. positive regulation of protein catabolic process Source: Ensembl
  31. positive regulation of striated muscle tissue development Source: Ensembl
  32. positive regulation of vasoconstriction Source: Ensembl
  33. positive regulation of vasodilation Source: Ensembl
  34. protein oligomerization Source: Ensembl
  35. regulation of atrial cardiac muscle cell membrane depolarization Source: Ensembl
  36. regulation of bone mineralization Source: Ensembl
  37. regulation of bone remodeling Source: Ensembl
  38. regulation of calcium ion transport Source: Ensembl
  39. regulation of tight junction assembly Source: Ensembl
  40. regulation of ventricular cardiac muscle cell membrane depolarization Source: Ensembl
  41. regulation of ventricular cardiac muscle cell membrane repolarization Source: Ensembl
  42. response to fluid shear stress Source: Ensembl
  43. response to peptide hormone Source: Ensembl
  44. response to pH Source: Ensembl
  45. skeletal muscle tissue regeneration Source: Ensembl
  46. vascular transport Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50990, highly similar to Gap junction alpha-1 proteinImported
Submitted name:
cDNA, FLJ79058, highly similar to Gap junction alpha-1 proteinImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation. Cell junctiongap junction SAAS annotation

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. connexon complex Source: InterPro
  3. contractile fiber Source: Ensembl
  4. cytosol Source: Ensembl
  5. early endosome Source: Ensembl
  6. fascia adherens Source: Ensembl
  7. Golgi apparatus Source: Ensembl
  8. integral component of membrane Source: UniProtKB-KW
  9. intermediate filament Source: Ensembl
  10. lateral plasma membrane Source: Ensembl
  11. lysosome Source: Ensembl
  12. membrane raft Source: Ensembl
  13. mitochondrial outer membrane Source: Ensembl
  14. multivesicular body Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Gap junctionSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiB4DMC9.
ExpressionAtlasiB4DMC9. baseline and differential.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG009576.

Family and domain databases

InterProiIPR000500. Connexin.
IPR002261. Connexin43.
IPR013124. Connexin43_C.
IPR019570. Connexin_CCC.
IPR017990. Connexin_CS.
[Graphical view]
PANTHERiPTHR11984. PTHR11984. 1 hit.
PfamiPF03508. Connexin43. 1 hit.
PF10582. Connexin_CCC. 1 hit.
[Graphical view]
PRINTSiPR00206. CONNEXIN.
PR01132. CONNEXINA1.
SMARTiSM01089. Connexin_CCC. 1 hit.
[Graphical view]
PROSITEiPS00408. CONNEXINS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DMC9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKEEKLNKK EEELKVAQTD GVNVDMHLKQ IEIKKFKYGI EEHGKVKMRG
60 70 80 90 100
GLLRTYIISI LFKSIFEVAF LLIQWYIYGF SLSAVYTCKR DPCPHQVDCF
110 120 130 140 150
LSRPTEKTIF IIFMLVVSLV SLALNIIELF YVFFKGVKDR VKGKSDPYHA
160 170 180 190 200
TSGALSPAKD CGSQKYAYFN GCSSPTAPLS PMSPPGYKLV TGDRNNSSCR
210 220 230 240 250
NYNKQASEQN WANYSAEQNR MGQAGSTISN SHAQPFDFPD DNQNSKKLAA
260 270 280
GHELQPLAIV DQRPSSRASS RASSRPRPDD LEI
Length:283
Mass (Da):31,864
Last modified:September 23, 2008 - v1
Checksum:i6C4B79EE24F63AA6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK297402 mRNA. Translation: BAG59841.1.
AK316159 mRNA. Translation: BAH14530.1.

Genome annotation databases

UCSCiuc011ebp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK297402 mRNA. Translation: BAG59841.1 .
AK316159 mRNA. Translation: BAH14530.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc011ebp.1. human.

Phylogenomic databases

HOVERGENi HBG009576.

Miscellaneous databases

NextBioi 35473288.

Gene expression databases

Bgeei B4DMC9.
ExpressionAtlasi B4DMC9. baseline and differential.

Family and domain databases

InterProi IPR000500. Connexin.
IPR002261. Connexin43.
IPR013124. Connexin43_C.
IPR019570. Connexin_CCC.
IPR017990. Connexin_CS.
[Graphical view ]
PANTHERi PTHR11984. PTHR11984. 1 hit.
Pfami PF03508. Connexin43. 1 hit.
PF10582. Connexin_CCC. 1 hit.
[Graphical view ]
PRINTSi PR00206. CONNEXIN.
PR01132. CONNEXINA1.
SMARTi SM01089. Connexin_CCC. 1 hit.
[Graphical view ]
PROSITEi PS00408. CONNEXINS_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB4DMC9_HUMAN
AccessioniPrimary (citable) accession number: B4DMC9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.