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Protein
Submitted name:

NAD(P)H dehydrogenase [quinone] 1

Gene

NQO1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NAD(P)H dehydrogenase [quinone] 1Imported
Submitted name:
cDNA FLJ50573, highly similar to Homo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 3, mRNAImported
Gene namesi
Name:NQO1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

HGNCiHGNC:2874. NQO1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000181019.

PTM / Processingi

Proteomic databases

MaxQBiB4DLR8.
PeptideAtlasiB4DLR8.
PRIDEiB4DLR8.

Expressioni

Gene expression databases

BgeeiENSG00000181019.
ExpressionAtlasiB4DLR8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000319788.

Structurei

3D structure databases

ProteinModelPortaliB4DLR8.
SMRiB4DLR8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 102Flavodoxin_2InterPro annotationAdd BLAST98

Phylogenomic databases

eggNOGiENOG410IKWF. Eukaryota.
COG2249. LUCA.
GeneTreeiENSGT00440000033410.
HOGENOMiHOG000149970.
HOVERGENiHBG029104.

Family and domain databases

Gene3Di3.40.50.360. 2 hits.
InterProiIPR003680. Flavodoxin_fold.
IPR029039. Flavoprotein-like_dom.
[Graphical view]
PfamiPF02525. Flavodoxin_2. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DLR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGRRALIVL AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI
60 70 80 90 100
ISRKDITGKL KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF
110 120 130 140 150
QSGILHFCGF QVLEPQLTYS IGHTPADARI QILEGWKKRL ENIWDETPLY
160 170 180 190 200
FAPSSLFDLN FQAGFLMKKE VQDEEKNKKF GLSVGHHLGK SIPTDNQIKA

RK
Length:202
Mass (Da):22,793
Last modified:September 23, 2008 - v1
Checksum:i845809C562CA8320
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092115 Genomic DNA. No translation available.
AK297125 mRNA. Translation: BAG59630.1.
RefSeqiNP_001273066.1. NM_001286137.1.
UniGeneiHs.406515.

Genome annotation databases

EnsembliENST00000439109; ENSP00000398330; ENSG00000181019.
GeneIDi1728.
UCSCiuc010vll.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC092115 Genomic DNA. No translation available.
AK297125 mRNA. Translation: BAG59630.1.
RefSeqiNP_001273066.1. NM_001286137.1.
UniGeneiHs.406515.

3D structure databases

ProteinModelPortaliB4DLR8.
SMRiB4DLR8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000319788.

Proteomic databases

MaxQBiB4DLR8.
PeptideAtlasiB4DLR8.
PRIDEiB4DLR8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000439109; ENSP00000398330; ENSG00000181019.
GeneIDi1728.
UCSCiuc010vll.4. human.

Organism-specific databases

CTDi1728.
HGNCiHGNC:2874. NQO1.
OpenTargetsiENSG00000181019.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IKWF. Eukaryota.
COG2249. LUCA.
GeneTreeiENSGT00440000033410.
HOGENOMiHOG000149970.
HOVERGENiHBG029104.

Miscellaneous databases

ChiTaRSiNQO1. human.
GenomeRNAii1728.

Gene expression databases

BgeeiENSG00000181019.
ExpressionAtlasiB4DLR8. baseline and differential.

Family and domain databases

Gene3Di3.40.50.360. 2 hits.
InterProiIPR003680. Flavodoxin_fold.
IPR029039. Flavoprotein-like_dom.
[Graphical view]
PfamiPF02525. Flavodoxin_2. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB4DLR8_HUMAN
AccessioniPrimary (citable) accession number: B4DLR8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.