Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B4DLN5

- B4DLN5_HUMAN

UniProt

B4DLN5 - B4DLN5_HUMAN

Protein
Submitted name:

SH2B adapter protein 1

Gene

SH2B1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    SH2B adapter protein 1Imported
    Submitted name:
    cDNA FLJ59336, highly similar to Homo sapiens SH2-B homolog (SH2B), mRNAImported
    Gene namesi
    Name:SH2B1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 16

    Organism-specific databases

    HGNCiHGNC:30417. SH2B1.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA145148084.

    PTM / Processingi

    Keywords - PTMi

    PhosphoproteinSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliB4DLN5.
    SMRiB4DLN5. Positions 1-43, 184-291.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains PH domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000047355.
    HOVERGENiHBG103068.
    KOiK12459.

    Family and domain databases

    Gene3Di3.30.505.10. 1 hit.
    InterProiIPR001849. PH_domain.
    IPR000980. SH2.
    [Graphical view]
    PfamiPF00169. PH. 1 hit.
    PF00017. SH2. 1 hit.
    [Graphical view]
    PRINTSiPR00401. SH2DOMAIN.
    SMARTiSM00252. SH2. 1 hit.
    [Graphical view]
    SUPFAMiSSF55550. SSF55550. 1 hit.
    PROSITEiPS50003. PH_DOMAIN. 1 hit.
    PS50001. SH2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4DLN5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPDRENTFVV KVEGPSEYIM ETVDAQHVKA WVSDIQECLS PGPCPATSPR    50
    PMTLPLAPGT SFLTRENTDS LELSCLNHSE SLPSQDLLLG PSESNDRLSQ 100
    GAYGGLSDRP SASISPSSAS IAASHFDSME LLPPELPPRI PIEEGPPTGT 150
    VHPLSAPYPP LDTPETATGS FLFQGEPEGG EGDQPLSGYP WFHGMLSRLK 200
    AAQLVLTGGT GSHGVFLVRQ SETRRGEYVL TFNFQGKAKH LRLSLNEEGQ 250
    CRVQHLWFQS IFDMLEHFRV HPIPLESGGS SDVVLVSYVP SSQRQQGREQ 300
    AGSHAGVCEG DGCHPDASCT LMPFGASDCV TDHLP 335
    Length:335
    Mass (Da):36,098
    Last modified:September 23, 2008 - v1
    Checksum:iDFFC08365A14A272
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC133550 Genomic DNA. No translation available.
    AK297080 mRNA. Translation: BAG59597.1.
    RefSeqiNP_001139267.1. NM_001145795.1.
    NP_001139268.1. NM_001145796.1.
    NP_001139269.1. NM_001145797.1.
    XP_005255297.1. XM_005255240.1.
    UniGeneiHs.15744.

    Genome annotation databases

    EnsembliENST00000538342; ENSP00000438784; ENSG00000178188.
    GeneIDi25970.
    KEGGihsa:25970.
    UCSCiuc010vdd.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC133550 Genomic DNA. No translation available.
    AK297080 mRNA. Translation: BAG59597.1 .
    RefSeqi NP_001139267.1. NM_001145795.1.
    NP_001139268.1. NM_001145796.1.
    NP_001139269.1. NM_001145797.1.
    XP_005255297.1. XM_005255240.1.
    UniGenei Hs.15744.

    3D structure databases

    ProteinModelPortali B4DLN5.
    SMRi B4DLN5. Positions 1-43, 184-291.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000538342 ; ENSP00000438784 ; ENSG00000178188 .
    GeneIDi 25970.
    KEGGi hsa:25970.
    UCSCi uc010vdd.2. human.

    Organism-specific databases

    CTDi 25970.
    HGNCi HGNC:30417. SH2B1.
    PharmGKBi PA145148084.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000047355.
    HOVERGENi HBG103068.
    KOi K12459.

    Miscellaneous databases

    GenomeRNAii 25970.
    NextBioi 47602.

    Family and domain databases

    Gene3Di 3.30.505.10. 1 hit.
    InterProi IPR001849. PH_domain.
    IPR000980. SH2.
    [Graphical view ]
    Pfami PF00169. PH. 1 hit.
    PF00017. SH2. 1 hit.
    [Graphical view ]
    PRINTSi PR00401. SH2DOMAIN.
    SMARTi SM00252. SH2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55550. SSF55550. 1 hit.
    PROSITEi PS50003. PH_DOMAIN. 1 hit.
    PS50001. SH2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
      , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
      Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Cord bloodImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB4DLN5_HUMAN
    AccessioniPrimary (citable) accession number: B4DLN5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3