Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrierImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000262660.1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000262660

PTM / Processingi

Proteomic databases

MaxQBiB4DLN1
PeptideAtlasiB4DLN1
PRIDEiB4DLN1

Expressioni

Gene expression databases

BgeeiENSG00000262660

Interactioni

Protein-protein interaction databases

IntActiB4DLN1, 5 interactors
STRINGi9606.ENSP00000461324

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 113Ribosomal_L12_NInterPro annotationAdd BLAST51
Domaini130 – 197Ribosomal_L12InterPro annotationAdd BLAST68
Repeati169 – 243SolcarPROSITE-ProRule annotationAdd BLAST75
Repeati256 – 343SolcarPROSITE-ProRule annotationAdd BLAST88
Repeati352 – 435SolcarPROSITE-ProRule annotationAdd BLAST84

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili174 – 198Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0759 Eukaryota
KOG1715 Eukaryota
ENOG410XQHU LUCA
GeneTreeiENSGT00760000119170
OMAiNTFTHFI
OrthoDBiEOG091G0BQ7

Family and domain databases

CDDicd00387 Ribosomal_L7_L12, 1 hit
Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002030 Mit_uncoupling_UCP-like
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
IPR000206 Ribosomal_L7/12
IPR014719 Ribosomal_L7/12_C/ClpS-like
IPR013823 Ribosomal_L7/L12_C
IPR008932 Ribosomal_L7/L12_oligo
IPR036235 Ribosomal_L7/L12_oligo_N_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PF00542 Ribosomal_L12, 1 hit
PF16320 Ribosomal_L12_N, 1 hit
PRINTSiPR00784 MTUNCOUPLING
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001326 Ribosomal_L7/L12_C, 1 hit
SUPFAMiSSF103506 SSF103506, 1 hit
SSF48300 SSF48300, 1 hit
SSF54736 SSF54736, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

B4DLN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPAAARPLW GPCLGLRAAA FRLARRQVPC VCAVRHMRSS GHQRCEALAG
60 70 80 90 100
APLDNAPKEY PPKIQQLVQD IASLTLLEIS DLNELLKKTL KIQDVGLVPM
110 120 130 140 150
GGVMSGAVPA AAAQEAVEED IPIAKERTHF TVRLTEAKPV DKVKLIKEIK
160 170 180 190 200
NYIQGINLVQ AKKLVESLPQ EIKANVAKAE AEKIKAALEA TQQEVKLRMT
210 220 230 240 250
GMALRVVRTD GILALYSGLS ASLCRQMTYS LTRFAIYETV RDRVAKGSQG
260 270 280 290 300
PLPFHEKVLL GSVSGLAGGF VGTPADLVNV RMQNDVKLPQ GQRRNYAHAL
310 320 330 340 350
DGLYRVAREE GLRRLFSGAT MASSRGALVT VGQLSCYDQA KQLVLSTGYL
360 370 380 390 400
SDNIFTHFVA SFIAGGCATF LCQPLDVLKT RLMNSKGEYQ GVFHCAVETA
410 420 430 440
KLGPLAFYKG LVPAGIRLIP HTVLTFVFLE QLRKNFGIKV PS
Length:442
Mass (Da):48,099
Last modified:September 23, 2008 - v1
Checksum:iDBFAD8103CCADE6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139530 Genomic DNA No translation available.
AK297076 mRNA Translation: BAG59593.1

Genome annotation databases

EnsembliENST00000571730; ENSP00000461324; ENSG00000262660
UCSCiuc010wut.4 human

Similar proteinsi

Entry informationi

Entry nameiB4DLN1_HUMAN
AccessioniPrimary (citable) accession number: B4DLN1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health