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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Submitted name:
cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrierImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiB4DLN1.
MaxQBiB4DLN1.

Interactioni

Protein-protein interaction databases

IntActiB4DLN1. 5 interactions.
STRINGi9606.ENSP00000461324.

Structurei

3D structure databases

SMRiB4DLN1. Positions 174-434.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini63 – 11351Ribosomal_L12_NInterPro annotationAdd
BLAST
Domaini130 – 19768Ribosomal_L12InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili174 – 19825Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0759. Eukaryota.
KOG1715. Eukaryota.
ENOG410XQHU. LUCA.
GeneTreeiENSGT00760000119170.
OMAiNTFTHFI.
PhylomeDBiB4DLN1.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
3.30.1390.10. 1 hit.
InterProiIPR002030. Mit_uncoupling.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
PF00542. Ribosomal_L12. 1 hit.
PF16320. Ribosomal_L12_N. 1 hit.
[Graphical view]
PRINTSiPR00784. MTUNCOUPLING.
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF103506. SSF103506. 1 hit.
SSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DLN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPAAARPLW GPCLGLRAAA FRLARRQVPC VCAVRHMRSS GHQRCEALAG
60 70 80 90 100
APLDNAPKEY PPKIQQLVQD IASLTLLEIS DLNELLKKTL KIQDVGLVPM
110 120 130 140 150
GGVMSGAVPA AAAQEAVEED IPIAKERTHF TVRLTEAKPV DKVKLIKEIK
160 170 180 190 200
NYIQGINLVQ AKKLVESLPQ EIKANVAKAE AEKIKAALEA TQQEVKLRMT
210 220 230 240 250
GMALRVVRTD GILALYSGLS ASLCRQMTYS LTRFAIYETV RDRVAKGSQG
260 270 280 290 300
PLPFHEKVLL GSVSGLAGGF VGTPADLVNV RMQNDVKLPQ GQRRNYAHAL
310 320 330 340 350
DGLYRVAREE GLRRLFSGAT MASSRGALVT VGQLSCYDQA KQLVLSTGYL
360 370 380 390 400
SDNIFTHFVA SFIAGGCATF LCQPLDVLKT RLMNSKGEYQ GVFHCAVETA
410 420 430 440
KLGPLAFYKG LVPAGIRLIP HTVLTFVFLE QLRKNFGIKV PS
Length:442
Mass (Da):48,099
Last modified:September 23, 2008 - v1
Checksum:iDBFAD8103CCADE6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139530 Genomic DNA. No translation available.
AK297076 mRNA. Translation: BAG59593.1.

Genome annotation databases

EnsembliENST00000571730; ENSP00000461324; ENSG00000262660.
UCSCiuc010wut.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139530 Genomic DNA. No translation available.
AK297076 mRNA. Translation: BAG59593.1.

3D structure databases

SMRiB4DLN1. Positions 174-434.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB4DLN1. 5 interactions.
STRINGi9606.ENSP00000461324.

Proteomic databases

EPDiB4DLN1.
MaxQBiB4DLN1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000571730; ENSP00000461324; ENSG00000262660.
UCSCiuc010wut.4. human.

Phylogenomic databases

eggNOGiKOG0759. Eukaryota.
KOG1715. Eukaryota.
ENOG410XQHU. LUCA.
GeneTreeiENSGT00760000119170.
OMAiNTFTHFI.
PhylomeDBiB4DLN1.

Miscellaneous databases

ChiTaRSiSLC25A10. human.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
3.30.1390.10. 1 hit.
InterProiIPR002030. Mit_uncoupling.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
PF00542. Ribosomal_L12. 1 hit.
PF16320. Ribosomal_L12_N. 1 hit.
[Graphical view]
PRINTSiPR00784. MTUNCOUPLING.
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF103506. SSF103506. 1 hit.
SSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Cord bloodImported.
  3. Ensembl
    Submitted (JAN-2013) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiB4DLN1_HUMAN
AccessioniPrimary (citable) accession number: B4DLN1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 8, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.