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B4DKW2

- B4DKW2_HUMAN

UniProt

B4DKW2 - B4DKW2_HUMAN

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Protein
Submitted name:

cDNA FLJ56001, highly similar to Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. ATP-dependent helicase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW
  4. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HelicaseImported, Hydrolase

Keywords - Ligandi

ATP-binding, Metal-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56001, highly similar to Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiB4DKW2.

Expressioni

Gene expression databases

BgeeiB4DKW2.
ExpressionAtlasiB4DKW2. baseline and differential.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG080658.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
4.10.1000.10. 1 hit.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR006575. RWD-domain.
IPR009060. UBA-like.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000571. Znf_CCCH.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF05773. RWD. 1 hit.
PF00642. zf-CCCH. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00356. ZnF_C3H1. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS50030. UBA. 1 hit.
PS50103. ZF_C3H1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B4DKW2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSSVRRKGK PGKGGGKGSS RGGRGGRSHA SKSHGSGGGG GGGGGGGGGN
60 70 80 90 100
RKASSRIWDD GDDFCIFSES RRPSRPSNSN ISKGESRPKW KPKAKVPLQT
110 120 130 140 150
LHMTSENQEK VKALLRDLQE QDADAGSERG LSGEEEDDEP DCCNDERYWP
160 170 180 190 200
AGQEPSLVPD LDPLEYAGLA SVEPYVPEFT VSPFAVQKLS RYGFNTERCQ
210 220 230 240 250
AVLRMCDGDV GASLEHLLTQ CFSETFGERM KISEAVNQIS LDECMEQRQE
260 270 280 290 300
EAFALKSICG EKFIERIQNR VWTIGLELEY LTSRFRKSKP KESTKNVQEN
310 320 330 340 350
SLEICKFYLK GNCKFGSKCR FKHEVPPNQI VGRIERSVDD SHLNAIEDAS
360 370 380 390 400
FLYELEIRFS KDHKYPYQAP LVAFYSTNEN LPLACRLHIS EFLYDKALTF
410 420 430 440 450
AETSEPVVYS LITLLEEESE IVKLLTNTHH KYSDPPVNFL PVPSRTRINN
460 470 480 490 500
PACHKTVIPN NSFVSNQIPE VEKASESEES DEDDGPAPVI VENESYVNLK
510 520 530 540 550
KKISKRYDWQ AKSVHAENGK ICKQFRMKQA SRQFQSILQE RQSLPAWEER
560 570 580 590 600
ETILNLLRKH QVVVISGMTG CGKTTQIPQF ILDDSLNGPP EKVANIICTQ
610 620 630 640 650
PRRISAISVA ERVAKERAER VGLTVGYQIR LESVKSSATR LLYCTTGVLL
660 670 680 690 700
RRLEGDTALQ GVSHIIVDEV HERTEESDFL LLVLKDIVSQ RPGLQVILMS
710 720 730 740 750
ATLNAELFSD YFNSCPVITI PGRTFPVDQF FLEDAIAVTR YVLQDGSPYM
760 770 780 790 800
RSMKQISKEK LKARRNRTAF EEVEEDLRLS LHLQDQDSVK DAVPDQQLDF
810 820 830 840 850
KQLLARYKGV SKSVIKTMSI MDFEKVNLEL IEALLEWIVD GKHSYPPGAI
860 870 880 890 900
LVFLPGLAEI KMLYEQLQSN SLFNNRRSNR CVIHPLHSSL SSEEQQAVFV
910 920 930
KPPAGVTKII ISTNIAETSI TIDDVVYVID SG
Length:932
Mass (Da):104,488
Last modified:September 23, 2008 - v1
Checksum:i07BA35AF585F0C17
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei932 – 9321Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296739 mRNA. Translation: BAG59324.1.
UniGeneiHs.468226.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296739 mRNA. Translation: BAG59324.1 .
UniGenei Hs.468226.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B4DKW2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG080658.

Miscellaneous databases

NextBioi 35472888.

Gene expression databases

Bgeei B4DKW2.
ExpressionAtlasi B4DKW2. baseline and differential.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
4.10.1000.10. 1 hit.
InterProi IPR011545. DEAD/DEAH_box_helicase_dom.
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR006575. RWD-domain.
IPR009060. UBA-like.
IPR015940. UBA/transl_elong_EF1B_N_euk.
IPR000571. Znf_CCCH.
[Graphical view ]
Pfami PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF05773. RWD. 1 hit.
PF00642. zf-CCCH. 1 hit.
[Graphical view ]
SMARTi SM00487. DEXDc. 1 hit.
SM00356. ZnF_C3H1. 1 hit.
[Graphical view ]
SUPFAMi SSF46934. SSF46934. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEi PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS50030. UBA. 1 hit.
PS50103. ZF_C3H1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TongueImported.

Entry informationi

Entry nameiB4DKW2_HUMAN
AccessioniPrimary (citable) accession number: B4DKW2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.