Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Citrate synthase

Gene

CS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthaseUniRule annotation
Gene namesi
Name:CSImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000062485.18.
HGNCiHGNC:2422. CS.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000062485.

PTM / Processingi

Proteomic databases

EPDiB4DJV2.
MaxQBiB4DJV2.

Expressioni

Gene expression databases

BgeeiENSG00000062485.
ExpressionAtlasiB4DJV2. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiB4DJV2. 1 interactor.

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2617. Eukaryota.
COG0372. LUCA.
GeneTreeiENSGT00390000006813.
HOVERGENiHBG005336.

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 2 hits.
InterProiView protein in InterPro
IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase.
IPR019810. Citrate_synthase_AS.
IPR010109. Citrate_synthase_euk.
IPR036969. Citrate_synthase_sf.
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiView protein in Pfam
PF00285. Citrate_synt. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01793. cit_synth_euk. 1 hit.
PROSITEiView protein in PROSITE
PS00480. CITRATE_SYNTHASE. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DJV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNASCLVLAA RHASASSTNL KDILADLIPK EQARIKTFRQ QHGKTVVGQI
60 70 80 90 100
TVDMMYGGMR GMKGLVYETS VLDPDEGIRF RGFSIPECQK LLPKAKGGEE
110 120 130 140 150
PLPEGLFWLL VTGHIPTEEQ VSWLSKEWAK RAALPSHVVT MLDNFPTNLH
160 170 180 190 200
PMSQLSAAVT ALNSESNFAR AYAQGISRTK YWELIYEDSM DLIAKLPCVA
210 220 230 240 250
AKIYRNLYRE GSGIGAIDSN LDWSHNFTNM LGYTDHQFTE LTRLYLTIHS
260 270 280 290 300
DHEGGNVSAH TSHLVGSALS DPYLSFAAAM NGLAGPLHGL ANQEVLVWLT
310 320 330 340 350
QLQKEVGKDV SDEKLRDYIW NTLNSGRVVP GYGHAVLRKT DPRYTCQREF
360 370 380 390 400
ALKHLPNDPM FKLVAQLYKI VPNVLLEQGK AKNPWPNVDA HSGVLLQYYG
410 420 430 440 450
MTEMNYYTVL FGVSRALGVL AQLIWSRALG FPLERPKSMS TEGLMKFVDS

KSG
Length:453
Mass (Da):50,432
Last modified:September 23, 2008 - v1
Checksum:i464FA128AF14EA4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073896 Genomic DNA. No translation available.
AK296249 mRNA. Translation: BAG58964.1.
UniGeneiHs.743252.

Genome annotation databases

EnsembliENST00000542324; ENSP00000440543; ENSG00000062485.
UCSCiuc010sql.2. human.

Similar proteinsi

Entry informationi

Entry nameiB4DJV2_HUMAN
AccessioniPrimary (citable) accession number: B4DJV2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 25, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported