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Protein
Submitted name:

cDNA FLJ58799, highly similar to Cyclic AMP-dependent transcription factor ATF-4

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl

GO - Biological processi

  1. gamma-aminobutyric acid signaling pathway Source: Ensembl
  2. gluconeogenesis Source: Ensembl
  3. intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Source: Ensembl
  4. negative regulation of potassium ion transport Source: Ensembl
  5. positive regulation of neuron apoptotic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ58799, highly similar to Cyclic AMP-dependent transcription factor ATF-4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. dendrite membrane Source: Ensembl
  3. nucleus Source: Ensembl
  4. transcription factor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB4DJD4.
ExpressionAtlasiB4DJD4. baseline and differential.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004301.

Family and domain databases

InterProiIPR029811. ATF4.
IPR004827. bZIP.
[Graphical view]
PANTHERiPTHR13044:SF2. PTHR13044:SF2. 1 hit.
PfamiPF00170. bZIP_1. 1 hit.
[Graphical view]
SMARTiSM00338. BRLZ. 1 hit.
[Graphical view]
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DJD4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLEKMDLKEF DLDALLGIDD LETMPDDLLT TLDDTCDLFA PLVQETNKQP
60 70 80 90 100
PQTVNPIGHL PESLTKPDQV APFTFLQPLP LSPGVLSSTP DHSFSLELGS
110 120 130 140 150
EVDITEGDRK PDYTAYVAMI PQCIKEEDTP SDNDSGICMS PESYLGSPQH
160 170 180 190 200
SPSTRGSPNR SLPSPGVLCG SARPKPYDPP GEKMVAAKVK GEKLDKKLKK
210 220 230 240 250
MEQNKTAATR YRQKKRAEQE ALTGECKELE KKNEALKERA DSLAKEIQYL
260
KDLIEEVRKA RGKKRVP
Length:267
Mass (Da):29,606
Last modified:September 23, 2008 - v1
Checksum:i058B02A5333B80AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296028 mRNA. Translation: BAG58796.1.
UniGeneiHs.496487.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296028 mRNA. Translation: BAG58796.1.
UniGeneiHs.496487.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG004301.

Miscellaneous databases

NextBioi35472503.

Gene expression databases

BgeeiB4DJD4.
ExpressionAtlasiB4DJD4. baseline and differential.

Family and domain databases

InterProiIPR029811. ATF4.
IPR004827. bZIP.
[Graphical view]
PANTHERiPTHR13044:SF2. PTHR13044:SF2. 1 hit.
PfamiPF00170. bZIP_1. 1 hit.
[Graphical view]
SMARTiSM00338. BRLZ. 1 hit.
[Graphical view]
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Subthalamic nucleusImported.

Entry informationi

Entry nameiB4DJD4_HUMAN
AccessioniPrimary (citable) accession number: B4DJD4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 7, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.