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Protein
Submitted name:

Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa, isoform CRA_c

Gene

POLR2E

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Submitted name:
Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa, isoform CRA_cImported
Submitted name:
cDNA FLJ55074, highly similar to DNA-directed RNA polymerase II 23 kDa polypeptide (EC 2.7.7.6)Imported
Gene namesi
Name:POLR2EImported
ORF Names:hCG_21572Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

DNA-directed RNA polymeraseImported

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DJ89.
PRIDEiB4DJ89.

Expressioni

Gene expression databases

BgeeiENSG00000099817.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000215587.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 116RNA_pol_Rpb5_CInterPro annotationAdd BLAST73

Phylogenomic databases

eggNOGiKOG3218. Eukaryota.
COG2012. LUCA.

Family and domain databases

Gene3Di3.40.1340.10. 1 hit.
3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5. 1 hit.
InterProiIPR005571. RNA_pol_Rpb5_N.
IPR000783. RNA_pol_subH/Rpb5_C.
IPR020608. RNA_pol_subH/Rpb5_CS.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
[Graphical view]
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF53036. SSF53036. 1 hit.
SSF55287. SSF55287. 1 hit.
PROSITEiPS01110. RNA_POL_H_23KD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DJ89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQEENITRAL IVVQQGMTPS AKQSLVDMAP KYILEQFLQQ ELLINITEHE
60 70 80 90 100
LVPEHVVMTK EEVTELLARY KLRENQLPRI QAGDPVARYF GIKRGQVVKI
110
IRPSETAGRY ITYRLVQ
Length:117
Mass (Da):13,548
Last modified:September 23, 2008 - v1
Checksum:iB50927667A951F12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295975 mRNA. Translation: BAG58751.1.
CH471139 Genomic DNA. Translation: EAW69550.1.
RefSeqiNP_001303252.1. NM_001316323.1.
NP_001303253.1. NM_001316324.1.
UniGeneiHs.24301.

Genome annotation databases

GeneIDi5434.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295975 mRNA. Translation: BAG58751.1.
CH471139 Genomic DNA. Translation: EAW69550.1.
RefSeqiNP_001303252.1. NM_001316323.1.
NP_001303253.1. NM_001316324.1.
UniGeneiHs.24301.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000215587.

Proteomic databases

PeptideAtlasiB4DJ89.
PRIDEiB4DJ89.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5434.

Organism-specific databases

CTDi5434.

Phylogenomic databases

eggNOGiKOG3218. Eukaryota.
COG2012. LUCA.

Miscellaneous databases

ChiTaRSiPOLR2E. human.

Gene expression databases

BgeeiENSG00000099817.

Family and domain databases

Gene3Di3.40.1340.10. 1 hit.
3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5. 1 hit.
InterProiIPR005571. RNA_pol_Rpb5_N.
IPR000783. RNA_pol_subH/Rpb5_C.
IPR020608. RNA_pol_subH/Rpb5_CS.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
[Graphical view]
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF53036. SSF53036. 1 hit.
SSF55287. SSF55287. 1 hit.
PROSITEiPS01110. RNA_POL_H_23KD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DJ89_HUMAN
AccessioniPrimary (citable) accession number: B4DJ89
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 5, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.