UniProtKB - B4DIP4 (B4DIP4_HUMAN)
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Protein
Submitted name:
cDNA FLJ58724, highly similar to Eukaryotic translation initiation factor2-alpha kinase 1 (EC 2.7.11.1)
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- protein kinase activity Source: InterPro
- translation initiation factor activity Source: UniProtKB-KW
Keywordsi
Molecular function | Initiation factorImported, KinaseImported, Transferase |
Biological process | Protein biosynthesis |
Enzyme and pathway databases
SignaLinki | B4DIP4. |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ58724, highly similar to Eukaryotic translation initiation factor2-alpha kinase 1 (EC 2.7.11.1)Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 459 | Protein kinaseInterPro annotationAdd BLAST | 417 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 464 – 493 | Sequence analysisAdd BLAST | 30 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | ENOG410ISBT. Eukaryota. ENOG410YD23. LUCA. |
HOVERGENi | HBG051429. |
Family and domain databases
InterProi | View protein in InterPro IPR011009. Kinase-like_dom_sf. IPR000719. Prot_kinase_dom. IPR017441. Protein_kinase_ATP_BS. IPR008271. Ser/Thr_kinase_AS. |
Pfami | View protein in Pfam PF00069. Pkinase. 2 hits. |
SMARTi | View protein in SMART SM00220. S_TKc. 1 hit. |
SUPFAMi | SSF56112. SSF56112. 2 hits. |
PROSITEi | View protein in PROSITE PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. |
i Sequence
Sequence statusi: Complete.
B4DIP4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNQTHFVQDR CLSDPCEDIS RIQKIRSREV ALEAQTSRYL NEFEELAILG
60 70 80 90 100
KGGYGRVYKV RNKLDGQYYA IKKILIKGAT KTVCMKVLRE VKVLAGLQHP
110 120 130 140 150
NIVGYHTAWI EHVHVIQPRA DRAAIELPSL EVLSDQEEDR EQCGVKNDES
160 170 180 190 200
SSSSIIFAEP TPEKEKRFGE SDTENQNNKS VKYTTNLVIR ESGELESTLE
210 220 230 240 250
LQENGLAGLS ASSIVEQQLP LRRNSHLEES FTSTEESSEE NVNFLGQTEA
260 270 280 290 300
QYHLMLHIQM QLCELSLWDW IVERNKRGRE YVDESACPYV MANVATKIFQ
310 320 330 340 350
ELVEGVFYIH NMGIVHRDLK PRNIFLHGPD QQVKIGDFGL ACTDILQKNT
360 370 380 390 400
DWTNRNGKRT PTHTSRVGTC LYASPEQLEG SEYDAKSDMY SLGVVLLELF
410 420 430 440 450
QPFGTEMERA EVLTGLRTGQ LPESLRKRCP VQAKYIQHLT RRNSSQRPSA
460 470 480 490 500
IQLLQSELFQ NSGNVNLTLQ MKIIEQEKEI AELKKQLNLL SQDKGFSVIP
510 520 530 540 550
KPHPCKALYS APQMISRQLR SLSCLCPALF PGTSSFIVAL SSPANLYIPQ
560 570
RQRSDELVFE SQKGSAMELA VITVDGV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK295712 mRNA. Translation: BAG58556.1. |
UniGenei | Hs.520205. |
Similar proteinsi
Entry informationi
Entry namei | B4DIP4_HUMAN | |
Accessioni | B4DIP4Primary (citable) accession number: B4DIP4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | February 28, 2018 | |
This is version 73 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |