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B4DII7

- B4DII7_HUMAN

UniProt

B4DII7 - B4DII7_HUMAN

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Protein
Submitted name: cDNA FLJ50741, highly similar to Glutamate (NMDA) receptor subunit epsilon 1
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. extracellular-glutamate-gated ion channel activity Source: InterPro
  2. ionotropic glutamate receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Ion channel, Ligand-gated ion channelSAAS annotations, ReceptorSAAS annotationsImported

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ50741, highly similar to Glutamate (NMDA) receptor subunit epsilon 1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cell junction Source: UniProtKB-KW
    2. integral component of membrane Source: UniProtKB-KW
    3. postsynaptic membrane Source: UniProtKB-KW
    Complete GO annotation...

    Keywords - Cellular componenti

    Cell junction, Cell membraneSAAS annotations, Membrane, Postsynaptic cell membraneSAAS annotations, Synapse

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA28979.

    PTM / Processingi

    Proteomic databases

    PRIDEiB4DII7.

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotations

    Phylogenomic databases

    HOVERGENiHBG052635.
    KOiK05209.

    Family and domain databases

    InterProiIPR001828. ANF_lig-bd_rcpt.
    IPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR018884. NMDAR2_C.
    IPR028082. Peripla_BP_I.
    IPR001638. SBP_bac_3.
    [Graphical view]
    PfamiPF01094. ANF_receptor. 1 hit.
    PF00060. Lig_chan. 1 hit.
    PF10565. NMDAR2_C. 1 hit.
    PF00497. SBP_bac_3. 1 hit.
    [Graphical view]
    PRINTSiPR00177. NMDARECEPTOR.
    SMARTiSM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view]
    SUPFAMiSSF53822. SSF53822. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4DII7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKIMQDYDW HVFSLVTTIF PGYREFISFV KTTVDNSFVG WDMQNVITLD     50
    TSFEDAKTQV QLKKIHSSVI LLYCSKDEAV LILSEARSLG LTGYDFFWIV 100
    PSLVSGNTEL IPKEFPSGLI SVSYDDWDYS LEARVRDGIG ILTTAASSML 150
    EKFSYIPEAK ASCYGQMERP EVPMHTLHPF MVNVTWDGKD LSFTEEGYQV 200
    HPRLVVIVLN KDREWEKVGK WENHTLSLRH AVWPRYKSFS DCEPDDNHLS 250
    IVTLEEAPFV IVEDIDPLTE TCVRNTVPCR KFVKINNSTN EGMNVKKCCK 300
    GFCIDILKKL SRTVKFTYDL YLVTNGKHGK KVNNVWNGMI GEVVYQRAVM 350
    AVGSLTINEE RSEVVDFSVP FVETGISVMV SRSNGTVSPS AFLEPFSASV 400
    WVMMFVMLLI VSAIAVFVFE YFSPVGYNRN LAKGKAPHGP SFTIGKAIWL 450
    LWGLVFNNSV PVQNPKGTTS KIMVSVWAFF AVIFLASYTA NLAAFMIQEE 500
    FVDQVTGLSD KKFQRPHDYS PPFRFGTVPN GSTERNIRNN YPYMHQYMTK 550
    FNQKGVEDAL VSLKTGKLDA FIYDAAVLNY KAGRDEGCKL VTIGSGYIFA 600
    TTGYGIALQK GSPWKRQIDL ALLQFVGDGE MEELETLWLT GICHNEKNEV 650
    MSSQLDIDNM AGVFYMLAAA MALSLITFIW EHLFYWKLRF CFTGVCSDRP 700
    GLLFSISRGI YSCIHGVHIE EKKKSPDFNL TGSQSNMLKL LRSAKNISSM 750
    SNMNSSRMDS PKRAADFIQR GSLIMDMVSD KGNLMYSDNR SFQGKESIFG 800
    DNMNELQTFV ANRQKDNLNN YVFQGQHPLT LNESNPNTVE VAVSTESKAN 850
    SRPRQLWKKS VDSIRQDSLS QNPVSQRDEA TAENRTHSLK SPRYLPEEMA 900
    HSDISETSNR ATCHREPDNS KNHKTKDNFK RSVASKYPKD CSEVERTYLK 950
    TKSSSPRDKI YTIDGEKEPG FHLDPPQFVE NVTLPENVDF PDPYQDPSEN 1000
    FRKGDSTLPM NRNPLHNEEG LSNKDQYKLY SKHFTLKDKG SPHSETSERY 1050
    RQNSTHCRSC LSNMPTYSGH FTMRSPFKCD ACLRMGNLHD IDEDQMLQET 1100
    GMTNAWLLGD APRTLTNTRC HPRR 1124
    Length:1,124
    Mass (Da):127,609
    Last modified:September 23, 2008 - v1
    Checksum:i183311901E07BF3E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK295620 mRNA. Translation: BAG58499.1.
    UniGeneiHs.411472.

    Genome annotation databases

    KEGGihsa:2903.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK295620 mRNA. Translation: BAG58499.1 .
    UniGenei Hs.411472.

    3D structure databases

    ModBasei Search...

    Proteomic databases

    PRIDEi B4DII7.

    Protocols and materials databases

    DNASUi 2903.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    KEGGi hsa:2903.

    Organism-specific databases

    CTDi 2903.
    PharmGKBi PA28979.

    Phylogenomic databases

    HOVERGENi HBG052635.
    KOi K05209.

    Miscellaneous databases

    GenomeRNAii 2903.
    NextBioi 11495.

    Family and domain databases

    InterProi IPR001828. ANF_lig-bd_rcpt.
    IPR019594. Glu_rcpt_Glu/Gly-bd.
    IPR001320. Iontro_glu_rcpt.
    IPR001508. NMDA_rcpt.
    IPR018884. NMDAR2_C.
    IPR028082. Peripla_BP_I.
    IPR001638. SBP_bac_3.
    [Graphical view ]
    Pfami PF01094. ANF_receptor. 1 hit.
    PF00060. Lig_chan. 1 hit.
    PF10565. NMDAR2_C. 1 hit.
    PF00497. SBP_bac_3. 1 hit.
    [Graphical view ]
    PRINTSi PR00177. NMDARECEPTOR.
    SMARTi SM00918. Lig_chan-Glu_bd. 1 hit.
    SM00079. PBPe. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53822. SSF53822. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: HippocampusImported.

    Entry informationi

    Entry nameiB4DII7_HUMAN
    AccessioniPrimary (citable) accession number: B4DII7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: July 9, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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