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Protein
Submitted name:

M-phase inducer phosphatase 2

Gene

CDC25B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
M-phase inducer phosphatase 2Imported
Submitted name:
cDNA FLJ53333, highly similar to M-phase inducer phosphatase 2 (EC 3.1.3.48)Imported
Gene namesi
Name:CDC25BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:1726. CDC25B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101224.

PTM / Processingi

Proteomic databases

MaxQBiB4DIG0.
PeptideAtlasiB4DIG0.
PRIDEiB4DIG0.

Expressioni

Gene expression databases

BgeeiENSG00000101224.
ExpressionAtlasiB4DIG0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000245960.

Structurei

3D structure databases

ProteinModelPortaliB4DIG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini367 – 474RhodaneseInterPro annotationAdd BLAST108

Phylogenomic databases

eggNOGiKOG3772. Eukaryota.
COG5105. LUCA.
GeneTreeiENSGT00390000018747.
HOVERGENiHBG052501.

Family and domain databases

Gene3Di3.40.250.10. 1 hit.
InterProiIPR000751. MPI_Phosphatase.
IPR001763. Rhodanese-like_dom.
[Graphical view]
PfamiPF06617. M-inducer_phosp. 1 hit.
PF00581. Rhodanese. 1 hit.
[Graphical view]
PRINTSiPR00716. MPIPHPHTASE.
SMARTiSM00450. RHOD. 1 hit.
[Graphical view]
SUPFAMiSSF52821. SSF52821. 1 hit.
PROSITEiPS50206. RHODANESE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DIG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSETPKSQV GTLLFRSRSR LTHLSLSRRA SESSLSSESS ESSDAGLCMD
60 70 80 90 100
SPSPMDPHMA EQTFEQAIQA ASRIIRNEQF AIRRFQSMPV RLLGHSPVLR
110 120 130 140 150
NITNSQAPDG RRKSEAGSGA ASSSGEDKEN DGFVFKMPWK PTHPSSTHAL
160 170 180 190 200
AEWASRREAF AQRPSSAPDL MCLSPDRKME VEELSPLALG RFSLTPAEGD
210 220 230 240 250
TEEDDGFVDI LESDLKDDDA VPPGMESLIS APLVKTLEKE EEKDLVMYSK
260 270 280 290 300
CQRLFRSPSM PCSVIRPILK RLERPQDRDT PVQNKRRRSV TPPEEQQEAE
310 320 330 340 350
EPKARVLRSK SLCHDEIENL LDSDHRELIG DYSKAFLLQT VDGKHQDLKY
360 370 380 390 400
ISPETMVALL TGKFSNIVDK FVIVDCRYPY EYEGGHIKTA VNLPLERDAE
410 420 430 440 450
SFLLKSPIAP CSLDKRVILI FHCEFSSERG PRMCRFIRER DRAVNDYPSL
460 470 480 490 500
YYPEMYILKG GYKEFFPQHP NFCEPQDYRP MNHEAFKDEL KTFRLKTRSW
510
AGERSRRELC SRLQDQ
Length:516
Mass (Da):58,884
Last modified:September 23, 2008 - v1
Checksum:i862ADAFD01CC5A80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109804 Genomic DNA. No translation available.
AK295573 mRNA. Translation: BAG58472.1.
RefSeqiNP_001274445.1. NM_001287516.1.
UniGeneiHs.153752.

Genome annotation databases

EnsembliENST00000344256; ENSP00000339125; ENSG00000101224.
GeneIDi994.
UCSCiuc010zqk.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109804 Genomic DNA. No translation available.
AK295573 mRNA. Translation: BAG58472.1.
RefSeqiNP_001274445.1. NM_001287516.1.
UniGeneiHs.153752.

3D structure databases

ProteinModelPortaliB4DIG0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000245960.

Proteomic databases

MaxQBiB4DIG0.
PeptideAtlasiB4DIG0.
PRIDEiB4DIG0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000344256; ENSP00000339125; ENSG00000101224.
GeneIDi994.
UCSCiuc010zqk.3. human.

Organism-specific databases

CTDi994.
HGNCiHGNC:1726. CDC25B.
OpenTargetsiENSG00000101224.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3772. Eukaryota.
COG5105. LUCA.
GeneTreeiENSGT00390000018747.
HOVERGENiHBG052501.

Miscellaneous databases

ChiTaRSiCDC25B. human.
GenomeRNAii994.

Gene expression databases

BgeeiENSG00000101224.
ExpressionAtlasiB4DIG0. baseline and differential.

Family and domain databases

Gene3Di3.40.250.10. 1 hit.
InterProiIPR000751. MPI_Phosphatase.
IPR001763. Rhodanese-like_dom.
[Graphical view]
PfamiPF06617. M-inducer_phosp. 1 hit.
PF00581. Rhodanese. 1 hit.
[Graphical view]
PRINTSiPR00716. MPIPHPHTASE.
SMARTiSM00450. RHOD. 1 hit.
[Graphical view]
SUPFAMiSSF52821. SSF52821. 1 hit.
PROSITEiPS50206. RHODANESE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DIG0_HUMAN
AccessioniPrimary (citable) accession number: B4DIG0
Secondary accession number(s): E9PCK4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 30, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.