B4DHM5 (B4DHM5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Phosphoglycerate kinase RuleBase RU000532 EC=2.7.2.3 RuleBase RU000532
Organism	Homo sapiens (Human) EMBL BAG58187.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.
Subunit structure	Monomer By similarity. RuleBase RU000696
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Molecular function	Kinase RuleBase RU000532 EMBL BAG58187.1 Transferase
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: InterPro
Molecular_function	phosphoglycerate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DHM5 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 01BC9D52E4FD3A3A	FASTA	242	25,677
	10 20 30 40 50 60 MVGVNLPQKA GGFLMKKELN YFAKALESPE RPFLAILGGA KVADKIQLIN NMLDKVNEMI 70 80 90 100 110 120 IGGGMAFTFL KVLNNMEIGT SLFDEEGAKI VKDLMSKAEK NGVKITLPVD FVTADKFDEN 130 140 150 160 170 180 AKTGQATVAS GIPAGWMGLD CGPESSKKYA EAVTRAKQIV WNGPVGVFEW EAFARGTKAL 190 200 210 220 230 240 MDEVVKATSR GCITIIGGGD TATCCAKWNT EDKVSHVSTG GGASLELLEG KVLPGVDALS NI

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAG58187.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK295182 mRNA. Translation: BAG58187.1. AK298855 mRNA. Translation: BAG60978.1.
IPI	IPI00916818.
UniGene	Hs.78771.
3D structure databases
ProteinModelPortal	B4DHM5.
SMR	B4DHM5. Positions 1-242.
ModBase	Search...
Protein-protein interaction databases
STRING	B4DHM5.
Proteomic databases
PRIDE	B4DHM5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG008177.
Gene expression databases
ArrayExpress	B4DHM5.
Bgee	B4DHM5.
Family and domain databases
Gene3D	3.40.50.1270. 1 hit.
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. [Graphical view]
PANTHER	PTHR11406. PTHR11406. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PRINTS	PR00477. PHGLYCKINASE.
SUPFAM	SSF53748. PGK. 1 hit.
ProtoNet	Search...
Other
BindingDB	B4DHM5.
NextBio	35472050.

Entry information

Entry name

B4DHM5_HUMAN

Accession

Primary (citable) accession number: B4DHM5

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.