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Protein
Submitted name:

cDNA FLJ53738, highly similar to Aquaporin-4

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ53738, highly similar to Aquaporin-4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 54HelicalSequence analysisAdd BLAST22
Transmembranei66 – 85HelicalSequence analysisAdd BLAST20
Transmembranei97 – 116HelicalSequence analysisAdd BLAST20
Transmembranei136 – 157HelicalSequence analysisAdd BLAST22
Transmembranei169 – 191HelicalSequence analysisAdd BLAST23
Transmembranei211 – 233HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DHF5

Structurei

3D structure databases

ProteinModelPortaliB4DHF5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOGENOMiHOG000288286
HOVERGENiHBG000312

Family and domain databases

CDDicd00333 MIP, 1 hit
Gene3Di1.20.1080.10, 1 hit
InterProiView protein in InterPro
IPR023271 Aquaporin-like
IPR034294 Aquaporin_transptr
IPR000425 MIP
PANTHERiPTHR19139 PTHR19139, 2 hits
PfamiView protein in Pfam
PF00230 MIP, 2 hits
PRINTSiPR00783 MINTRINSICP
SUPFAMiSSF81338 SSF81338, 1 hit

Sequencei

Sequence statusi: Complete.

B4DHF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL
60 70 80 90 100
LSLGSTINWG GTEKPLPVDM VLISLCFGLS IATMVCTRKI SIAKSVFYIA
110 120 130 140 150
AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL
160 170 180 190 200
VFTIFASCDS KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP
210 220 230 240 250
AVIMGNWENH WIYWVGPIIG AVLAGGLYEY VFCPDVEFKR RFKEAFSKAA
260 270 280 290 300
QQTKGSYMEV EDNRSQVETD DLILKPGVVH VIDVDRGEEK KGKDQSGEVL

SSV
Length:303
Mass (Da):32,809
Last modified:September 23, 2008 - v1
Checksum:iCC3BC3AAB5E81B8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295069 mRNA Translation: BAG58116.1
UniGeneiHs.315369

Similar proteinsi

Entry informationi

Entry nameiB4DHF5_HUMAN
AccessioniPrimary (citable) accession number: B4DHF5
Secondary accession number(s): E7EWY1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: February 28, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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