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Protein
Submitted name:

cDNA FLJ53738, highly similar to Aquaporin-4

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ53738, highly similar to Aquaporin-4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 54HelicalSequence analysisAdd BLAST22
Transmembranei66 – 85HelicalSequence analysisAdd BLAST20
Transmembranei97 – 116HelicalSequence analysisAdd BLAST20
Transmembranei136 – 157HelicalSequence analysisAdd BLAST22
Transmembranei169 – 191HelicalSequence analysisAdd BLAST23
Transmembranei211 – 233HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DHF5.

Expressioni

Gene expression databases

BgeeiENSG00000171885.

Structurei

3D structure databases

ProteinModelPortaliB4DHF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000288286.
HOVERGENiHBG000312.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 2 hits.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 2 hits.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DHF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL
60 70 80 90 100
LSLGSTINWG GTEKPLPVDM VLISLCFGLS IATMVCTRKI SIAKSVFYIA
110 120 130 140 150
AQCLGAIIGA GILYLVTPPS VVGGLGVTMV HGNLTAGHGL LVELIITFQL
160 170 180 190 200
VFTIFASCDS KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP
210 220 230 240 250
AVIMGNWENH WIYWVGPIIG AVLAGGLYEY VFCPDVEFKR RFKEAFSKAA
260 270 280 290 300
QQTKGSYMEV EDNRSQVETD DLILKPGVVH VIDVDRGEEK KGKDQSGEVL

SSV
Length:303
Mass (Da):32,809
Last modified:September 23, 2008 - v1
Checksum:iCC3BC3AAB5E81B8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295069 mRNA. Translation: BAG58116.1.
UniGeneiHs.315369.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295069 mRNA. Translation: BAG58116.1.
UniGeneiHs.315369.

3D structure databases

ProteinModelPortaliB4DHF5.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiB4DHF5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000288286.
HOVERGENiHBG000312.

Gene expression databases

BgeeiENSG00000171885.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 2 hits.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 2 hits.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB4DHF5_HUMAN
AccessioniPrimary (citable) accession number: B4DHF5
Secondary accession number(s): E7EWY1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.