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Protein
Submitted name:

cDNA FLJ54601, highly similar to F-box/WD repeat protein 11

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiB4DH70.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ54601, highly similar to F-box/WD repeat protein 11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

EPDiB4DH70.
MaxQBiB4DH70.
PaxDbiB4DH70.
PeptideAtlasiB4DH70.
PRIDEiB4DH70.

Expressioni

Gene expression databases

BgeeiENSG00000072803.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiB4DH70. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliB4DH70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini97 – 135F-boxInterPro annotationAdd BLAST39
Domaini204 – 495WD_REPEATS_REGIONInterPro annotationAdd BLAST292
Repeati204 – 243WDPROSITE-ProRule annotationAdd BLAST40
Repeati244 – 283WDPROSITE-ProRule annotationAdd BLAST40
Repeati284 – 323WDPROSITE-ProRule annotationAdd BLAST40
Repeati327 – 366WDPROSITE-ProRule annotationAdd BLAST40
Repeati367 – 406WDPROSITE-ProRule annotationAdd BLAST40
Repeati407 – 439WDPROSITE-ProRule annotationAdd BLAST33
Repeati456 – 486WDPROSITE-ProRule annotationAdd BLAST31

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0281. Eukaryota.
ENOG410XTA8. LUCA.
HOGENOMiHOG000006638.
HOVERGENiHBG002521.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR021977. Beta-TrCP_D.
IPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF12125. Beta-TrCP_D. 1 hit.
PF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM01028. Beta-TrCP_D. 1 hit.
SM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEiView protein in PROSITE
PS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DH70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDQNEDESP KKNTLWQISN GTSSVIVSRK RPSEGNYQKE KDLCIKYFDQ
60 70 80 90 100
WSESDQVEFV EHLISRMCHY QHGHINSYLK PMLQRDFITA LPEQGLDHIA
110 120 130 140 150
ENILSYLDAR SLCAAELVCK EWQRVISEGM LWKKLIERMV RTDPLWKGLS
160 170 180 190 200
ERRGWDQYLF KNRPTDGPPN SFYRSLYPKI IQDIETIESN WRCGRHNLQR
210 220 230 240 250
IQCRSENSKG VYCLQYDDEK IISGLRDNSI KIWDKTSLEC LKVLTGHTGS
260 270 280 290 300
VLCLQYDERV IVTGSSDSTV RVWDVNTGEV LNTLIHHNEA VLHLRFSNGL
310 320 330 340 350
MVTCSKDRSI AVWDMASATD ITLRRVLVGH RAAVNVVDFD DKYIVSASGD
360 370 380 390 400
RTIKVWSTST CEFVRTLNGH KRGIACLQYR DRLVVSGSSD NTIRLWDIEC
410 420 430 440 450
GACLRVLEGH EELVRCIRFD NKRIVSGAYD GKIKVWDLQA ALDPRAPAST
460 470 480 490 500
LCLRTLVEHS GRVFRLQFDE FQIISSSHDD TILIWDFLNV PPSAQNETRS
510
PSRTYTYISR
Length:510
Mass (Da):58,765
Last modified:September 23, 2008 - v1
Checksum:iA1B3BC2C11792F1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK294956 mRNA. Translation: BAG58031.1.
RefSeqiXP_005265915.1. XM_005265858.2.
XP_016864769.1. XM_017009280.1.
UniGeneiHs.484138.

Genome annotation databases

GeneIDi23291.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB4DH70_HUMAN
AccessioniPrimary (citable) accession number: B4DH70
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 5, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.