Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Catenin beta-1

Gene

CTNNB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Catenin beta-1Imported
Submitted name:
cDNA FLJ57878, highly similar to Beta-cateninImported
Gene namesi
Name:CTNNB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000168036.16.
HGNCiHGNC:2514. CTNNB1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168036.

PTM / Processingi

Proteomic databases

EPDiB4DGU4.
MaxQBiB4DGU4.

Expressioni

Gene expression databases

BgeeiENSG00000168036.
ExpressionAtlasiB4DGU4. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiB4DGU4. 6 interactors.

Structurei

3D structure databases

SMRiB4DGU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati144 – 184ARMPROSITE-ProRule annotationAdd BLAST41
Repeati186 – 229ARMPROSITE-ProRule annotationAdd BLAST44
Repeati228 – 270ARMPROSITE-ProRule annotationAdd BLAST43
Repeati270 – 312ARMPROSITE-ProRule annotationAdd BLAST43
Repeati312 – 355ARMPROSITE-ProRule annotationAdd BLAST44
Repeati393 – 435ARMPROSITE-ProRule annotationAdd BLAST43
Repeati435 – 477ARMPROSITE-ProRule annotationAdd BLAST43
Repeati482 – 525ARMPROSITE-ProRule annotationAdd BLAST44
Repeati587 – 629ARMPROSITE-ProRule annotationAdd BLAST43

Phylogenomic databases

eggNOGiKOG4203. Eukaryota.
COG0035. LUCA.
GeneTreeiENSGT00730000110821.
HOGENOMiHOG000230958.
HOVERGENiHBG000919.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
PfamiView protein in Pfam
PF00514. Arm. 4 hits.
PRINTSiPR01869. BCATNINFAMLY.
SMARTiView protein in SMART
SM00185. ARM. 12 hits.
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiView protein in PROSITE
PS50176. ARM_REPEAT. 9 hits.

Sequencei

Sequence statusi: Complete.

B4DGU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELDMAMEPD RKAAVSHWQQ QSYLDSGIHS GATTTAPSLS GKGNPEEEDV
60 70 80 90 100
DTSQVLYEWE QGFSQSFTQE QVADIDGQYA MTRAQRVRAA MFPETLDEGM
110 120 130 140 150
QIPSTQFDAA HPTNVQRLAE PSQMLKHAVV NLINYQDDAE LATRAIPELT
160 170 180 190 200
KLLNDEDQVV VNKAAVMVHQ LSKKEASRHA IMRSPQMVSA IVRTMQNTND
210 220 230 240 250
VETARCTAGT LHNLSHHREG LLAIFKSGGI PALVKMLGSP VDSVLFYAIT
260 270 280 290 300
TLHNLLLHQE GAKMAVRLAG GLQKMVALLN KTNVKFLAIT TDCLQILAYG
310 320 330 340 350
NQESKLIILA SGGPQALVNI MRTYTYEKLL WTTSRVLKVL SVCSSNKPAI
360 370 380 390 400
VEAGGMQALG LHLTDPSQRL VQNCLWTLRN LSDAATKQEG MEGLLGTLVQ
410 420 430 440 450
LLGSDDINVV TCAAGILSNL TCNNYKNKMM VCQVGGIEAL VRTVLRAGDR
460 470 480 490 500
EDITEPAICA LRHLTSRHQE AEMAQNAVRL HYGLPVVVKL LHPPSHWPLI
510 520 530 540 550
KATVGLIRNL ALCPANHAPL REQGAIPRLV QLLVRAHQDT QRRTSMGGTQ
560 570 580 590 600
QQFVEGVRME EIVEGCTGAL HILARDVHNR IVIRGLNTIP LFVQLLYSPI
610 620 630 640 650
ENIQRVAAGV LCELAQDKEA AEAIEAEGAT APLTELLHSR NEGVATYAAA
660 670 680 690 700
VLFRMSEDKP QDYKKRLSVE LTSSLFRTEP MAWNETADLG LDIGAQGEPL
710 720 730 740 750
GYRQDDPSYR SFHSGGYGQD ALGMDPMMEH EMGGHHPGAD YPVDGLPDLG
760 770
HAQDLMDGLP PGDSNQLAWF DTDL
Length:774
Mass (Da):84,766
Last modified:September 23, 2008 - v1
Checksum:i785874CCE2EC6DC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104307 Genomic DNA. No translation available.
AK294778 mRNA. Translation: BAG57905.1.
RefSeqiNP_001317658.1. NM_001330729.1.
XP_006713046.1. XM_006712983.1.
XP_006713047.1. XM_006712984.1.
UniGeneiHs.476018.
Hs.712929.

Genome annotation databases

EnsembliENST00000453024; ENSP00000411226; ENSG00000168036.
GeneIDi1499.
UCSCiuc011azf.2. human.

Similar proteinsi

Entry informationi

Entry nameiB4DGU4_HUMAN
AccessioniPrimary (citable) accession number: B4DGU4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 25, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported