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Protein
Submitted name:

ATP-binding cassette sub-family B member 7, mitochondrial

Gene

ABCB7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi479 – 486ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

LigandATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette sub-family B member 7, mitochondrialImported
Submitted name:
cDNA FLJ53391, highly similar to ATP-binding cassette sub-family B member 7, mitochondrialImported
Gene namesi
Name:ABCB7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000131269.15
HGNCiHGNC:48 ABCB7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei114 – 139HelicalSequence analysisAdd BLAST26
Transmembranei159 – 180HelicalSequence analysisAdd BLAST22
Transmembranei234 – 261HelicalSequence analysisAdd BLAST28
Transmembranei267 – 288HelicalSequence analysisAdd BLAST22
Transmembranei357 – 379HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000131269

Expressioni

Gene expression databases

BgeeiENSG00000131269

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 410ABC transmembrane type-1InterPro annotationAdd BLAST296
Domaini446 – 680ABC transporterInterPro annotationAdd BLAST235

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0057 Eukaryota
COG5265 LUCA
GeneTreeiENSGT00440000033373
HOVERGENiHBG080810

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Fragment.

B4DGL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLAMHSWR WAAAAAAFEK RRHSAILIRP LVSVSGSGPQ WRPHQLGALG
60 70 80 90 100
TARAYQALQV WPLIEKRTCW HGHAGGGLHT DPKEGLKDVD TRKIIKAMLS
110 120 130 140 150
YVWPKDRPDL RARVAISLGF LGGAKAMNIV VPFMFKYAVD SLNQMSGNML
160 170 180 190 200
NLSDAPNTVA TMATAVLIGY GVSRAGAAFF NEVRNAVFGK VAQNSIRRIA
210 220 230 240 250
KNVFLHLHNL DLGFHLSRQT GALSKAIDRG TRGISFVLSA LVFNLLPIMF
260 270 280 290 300
EVMLVSGVLY YKCGAQFALV TLGTLGTYTA FTVAVTRWRT RFRIEMNKAD
310 320 330 340 350
NDAGNAAIDS LLNYETVKYF NNERYEAQRY DGFLKTYETA SLKSTSTLAM
360 370 380 390 400
LNFGQSAIFS VGLTAIMVLA SQGIVAGTLT VGDLVMVNGL LFQLSLPLNF
410 420 430 440 450
LGTVYRETRQ ALIDMNTLFT LLKVDTQIKD KVMASPLQIT PQTATVAFDN
460 470 480 490 500
VHFEYIEGQK VLSGISFEVP AGKKVAIVGG SGSGKSTIVR LLFRFYEPQK
510 520 530 540 550
GSIYLAGQNI QDVSLESLRR AVGVVPQDAV LFHNTIYYNL LYGNISASPE
560 570 580 590 600
EVYAVAKLAG LHDAILRMPH GYDTQVGERG LKLSGGEKQR VAIARAILKD
610 620 630 640 650
PPVILYDEAT SSLDSITEET ILGAMKDVVK HRTSIFIAHR LSTVVDADEI
660 670 680 690 700
IVLDQGKVAE RGTHHGLLAN PHSIYSEMWH TQSSRVQNHD NPKWEAKKEN

IS
Length:702
Mass (Da):77,121
Last modified:September 23, 2008 - v1
Checksum:i165821EACE3CB9E9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei702Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359545 Genomic DNA No translation available.
AL360179 Genomic DNA No translation available.
AL590232 Genomic DNA No translation available.
AK294657 mRNA Translation: BAG57829.1
UniGeneiHs.370480

Genome annotation databases

EnsembliENST00000529949; ENSP00000436586; ENSG00000131269
UCSCiuc065aab.1 human

Similar proteinsi

Entry informationi

Entry nameiB4DGL8_HUMAN
AccessioniPrimary (citable) accession number: B4DGL8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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