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B4DG79

- B4DG79_HUMAN

UniProt

B4DG79 - B4DG79_HUMAN

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Protein
Submitted name: cDNA FLJ55487, highly similar to RAC-beta serine/threonine-protein kinase (EC2.7.11.1)
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. activation of Ral GTPase activity Source: Ensembl
  2. insulin receptor signaling pathway Source: Ensembl
  3. intracellular protein transmembrane transport Source: Ensembl
  4. peripheral nervous system myelin maintenance Source: Ensembl
  5. positive regulation of glucose import in response to insulin stimulus Source: Ensembl
  6. positive regulation of protein phosphorylation Source: Ensembl
  7. positive regulation of protein targeting to membrane Source: Ensembl
  8. positive regulation of vesicle fusion Source: Ensembl
  9. protein localization to plasma membrane Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB4DG79.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ55487, highly similar to RAC-beta serine/threonine-protein kinase (EC2.7.11.1)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cell cortex Source: Ensembl
  2. ruffle membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB4DG79.

Expressioni

Gene expression databases

ArrayExpressiB4DG79.
BgeeiB4DG79.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliB4DG79.

Family & Domainsi

Sequence similaritiesi

Contains AGC-kinase C-terminal domain.SAAS annotations

Phylogenomic databases

HOVERGENiHBG108317.
KOiK04456.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view]
SMARTiSM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51285. AGC_KINASE_CTER. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DG79-1 [UniParc]FASTAAdd to Basket

« Hide

MKTERPRPNT FVIRCLQWTT VIERTFHVDS PDEREEWMRA IQMVANSLKQ    50
RAPGEDPMDY KCGSPSDSST TEEMEVAVSK ARAKVTMNDF DYLKLLGKGT 100
FGKVILVREK ATGRYYAMKI LRKEVIIAKD EVAHTVTESR VLQNTRHPFL 150
TALKYAFQTH DRLCFVMEYA NGGELFFHLS RERVFTEERA RFYGAEIVSA 200
LEYLHSRDVV YRDIKLENLM LDKDGHIKIT DFGLCKEGIS DGATMKTFCG 250
TPEYLAPEVL EDNDYGRAVD WWGLGVVMYE MMCGRLPFYN QDHERLFELI 300
LMEEIRFPRT LSPEAKSLLA GLLKKDPKQR LGGGPSDAKE VMEHRFFLSI 350
NWQDVVQKKL LPPFKPQVTS EVDTRYFDDE FTAQSITITP PDRYDSLGLL 400
ELDQRTHFPQ FSYSASIRE 419
Length:419
Mass (Da):48,502
Last modified:September 23, 2008 - v1
Checksum:i67AEDEBB2CDC2D53
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK294453 mRNA. Translation: BAG57690.1.
RefSeqiNP_001229956.1. NM_001243027.2.
NP_001229957.1. NM_001243028.2.
UniGeneiHs.631535.

Genome annotation databases

GeneIDi208.
KEGGihsa:208.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK294453 mRNA. Translation: BAG57690.1 .
RefSeqi NP_001229956.1. NM_001243027.2.
NP_001229957.1. NM_001243028.2.
UniGenei Hs.631535.

3D structure databases

ProteinModelPortali B4DG79.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi B4DG79.

Proteomic databases

PRIDEi B4DG79.

Protocols and materials databases

DNASUi 208.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 208.
KEGGi hsa:208.

Organism-specific databases

CTDi 208.

Phylogenomic databases

HOVERGENi HBG108317.
KOi K04456.

Enzyme and pathway databases

SignaLinki B4DG79.

Miscellaneous databases

GenomeRNAii 208.
NextBioi 836.

Gene expression databases

ArrayExpressi B4DG79.
Bgeei B4DG79.

Family and domain databases

Gene3Di 2.30.29.30. 1 hit.
InterProi IPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view ]
SMARTi SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51285. AGC_KINASE_CTER. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: AmygdalaImported.

Entry informationi

Entry nameiB4DG79_HUMAN
AccessioniPrimary (citable) accession number: B4DG79
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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