Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B4DG79

- B4DG79_HUMAN

UniProt

B4DG79 - B4DG79_HUMAN

Protein
Submitted name:

cDNA FLJ55487, highly similar to RAC-beta serine/threonine-protein kinase (EC2.7.11.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.SAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    GO - Biological processi

    1. activation of Ral GTPase activity Source: Ensembl
    2. insulin receptor signaling pathway Source: Ensembl
    3. intracellular protein transmembrane transport Source: Ensembl
    4. peripheral nervous system myelin maintenance Source: Ensembl
    5. positive regulation of glucose import in response to insulin stimulus Source: Ensembl
    6. positive regulation of protein phosphorylation Source: Ensembl
    7. positive regulation of protein targeting to membrane Source: Ensembl
    8. positive regulation of vesicle fusion Source: Ensembl
    9. protein localization to plasma membrane Source: Ensembl

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinaseSAAS annotation, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    SignaLinkiB4DG79.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ55487, highly similar to RAC-beta serine/threonine-protein kinase (EC2.7.11.1)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cell cortex Source: Ensembl
    2. ruffle membrane Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiB4DG79.

    Expressioni

    Gene expression databases

    ArrayExpressiB4DG79.
    BgeeiB4DG79.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliB4DG79.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains AGC-kinase C-terminal domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG108317.
    KOiK04456.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR000961. AGC-kinase_C.
    IPR011009. Kinase-like_dom.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR017892. Pkinase_C.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    PF00433. Pkinase_C. 1 hit.
    [Graphical view]
    SMARTiSM00133. S_TK_X. 1 hit.
    SM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51285. AGC_KINASE_CTER. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4DG79-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTERPRPNT FVIRCLQWTT VIERTFHVDS PDEREEWMRA IQMVANSLKQ    50
    RAPGEDPMDY KCGSPSDSST TEEMEVAVSK ARAKVTMNDF DYLKLLGKGT 100
    FGKVILVREK ATGRYYAMKI LRKEVIIAKD EVAHTVTESR VLQNTRHPFL 150
    TALKYAFQTH DRLCFVMEYA NGGELFFHLS RERVFTEERA RFYGAEIVSA 200
    LEYLHSRDVV YRDIKLENLM LDKDGHIKIT DFGLCKEGIS DGATMKTFCG 250
    TPEYLAPEVL EDNDYGRAVD WWGLGVVMYE MMCGRLPFYN QDHERLFELI 300
    LMEEIRFPRT LSPEAKSLLA GLLKKDPKQR LGGGPSDAKE VMEHRFFLSI 350
    NWQDVVQKKL LPPFKPQVTS EVDTRYFDDE FTAQSITITP PDRYDSLGLL 400
    ELDQRTHFPQ FSYSASIRE 419
    Length:419
    Mass (Da):48,502
    Last modified:September 23, 2008 - v1
    Checksum:i67AEDEBB2CDC2D53
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK294453 mRNA. Translation: BAG57690.1.
    RefSeqiNP_001229956.1. NM_001243027.2.
    NP_001229957.1. NM_001243028.2.
    UniGeneiHs.631535.

    Genome annotation databases

    GeneIDi208.
    KEGGihsa:208.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK294453 mRNA. Translation: BAG57690.1 .
    RefSeqi NP_001229956.1. NM_001243027.2.
    NP_001229957.1. NM_001243028.2.
    UniGenei Hs.631535.

    3D structure databases

    ProteinModelPortali B4DG79.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi B4DG79.

    Proteomic databases

    PRIDEi B4DG79.

    Protocols and materials databases

    DNASUi 208.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 208.
    KEGGi hsa:208.

    Organism-specific databases

    CTDi 208.

    Phylogenomic databases

    HOVERGENi HBG108317.
    KOi K04456.

    Enzyme and pathway databases

    SignaLinki B4DG79.

    Miscellaneous databases

    GenomeRNAii 208.
    NextBioi 836.

    Gene expression databases

    ArrayExpressi B4DG79.
    Bgeei B4DG79.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR000961. AGC-kinase_C.
    IPR011009. Kinase-like_dom.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR017892. Pkinase_C.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    PF00433. Pkinase_C. 1 hit.
    [Graphical view ]
    SMARTi SM00133. S_TK_X. 1 hit.
    SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51285. AGC_KINASE_CTER. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: AmygdalaImported.

    Entry informationi

    Entry nameiB4DG79_HUMAN
    AccessioniPrimary (citable) accession number: B4DG79
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.