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Protein
Submitted name:

cDNA FLJ56618, highly similar to Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Ribonucleoprotein, Ribosomal proteinImported, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB4DG22.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56618, highly similar to Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiB4DG22.
PaxDbiB4DG22.
PeptideAtlasiB4DG22.
PRIDEiB4DG22.

Structurei

3D structure databases

ProteinModelPortaliB4DG22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 299Protein kinaseInterPro annotationAdd BLAST260
Domaini300 – 369AGC-kinase C-terminalInterPro annotationAdd BLAST70
Domaini393 – 650Protein kinaseInterPro annotationAdd BLAST258

Phylogenomic databases

eggNOGiKOG0598. Eukaryota.
ENOG410XNPH. LUCA.
HOVERGENiHBG108317.

Family and domain databases

InterProiView protein in InterPro
IPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR016239. Ribosomal_S6_kinase_II.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 2 hits.
PF00433. Pkinase_C. 1 hit.
PIRSFiPIRSF000606. Ribsml_S6_kin_2. 1 hit.
SMARTiView protein in SMART
SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 2 hits.
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiView protein in PROSITE
PS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 2 hits.
PS50011. PROTEIN_KINASE_DOM. 2 hits.
PS00108. PROTEIN_KINASE_ST. 2 hits.

Sequencei

Sequence statusi: Complete.

B4DG22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEPMGEEEI NPQTEEVSIK EIAITHHVKE GHEKADPSQF ELLKVLGQGS
60 70 80 90 100
FGKVFLVKKI SGSDARQLYA MKVLKKATLK VRDRVRTKME RDILVEVNHP
110 120 130 140 150
FIVKLHYAFQ TEGKLYLILD FLRGGDLFTR LSKEVMFTEE DVKFYLAELA
160 170 180 190 200
LALDHLHSLG IIYRDLKPEN ILLDEEGHIK LTDFGLSKES IDHEKKAYSF
210 220 230 240 250
CGTVEYMAPE VVNRRGHTQS ADWWSFGVLM FEMLTGTLPF QGKDRKETMT
260 270 280 290 300
MILKAKLGMP QFLSPEAQSL LRMLFKRNPA NRLGAGPDGV EEIKRHSFFS
310 320 330 340 350
TIDWNKLYRR EIHPPFKPAT GRPEDTFYFD PEFTAKTPKD SPGIPPSANA
360 370 380 390 400
HQLFRGFSFV AITSDDESQA MQTVGVHSIV QLHRNSIQFT DGYEVKEDIG
410 420 430 440 450
VGSYSVCKRC IHKATNMEFA VKIIDKSKRD PTEEIEILLR YGQHPNIITL
460 470 480 490 500
KDVYDDGKYV YVVTELMKGG ELLDKILRQK FFSEREASAV LFTITKTVEY
510 520 530 540 550
LHAQGVVHRD LKPSNILYVD ESGNPESIRI CDFGFAKQLR AENGLLMTPC
560 570 580 590 600
YTANFVAPEV LKRQGYDAAC DIWSLGVLLY TMLTGYTPFA NGPDDTPEEI
610 620 630 640 650
LARIGSGKFS LSGGYWNSVS DTAKDLVSKM LHVDPHQRLT AALVLRHPWI
660 670 680 690 700
VHWDQLPQYQ LNRQDAPHLV KGAMAATYSA LNRNQSPVLE PVGRSTLAQR
710
RGIKKITSTA L
Length:711
Mass (Da):80,583
Last modified:September 23, 2008 - v1
Checksum:iD4383824A75BEB03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK294373 mRNA. Translation: BAG57633.1.
RefSeqiXP_006724570.1. XM_006724507.3.
XP_016885208.1. XM_017029719.1.
UniGeneiHs.445387.

Genome annotation databases

GeneIDi6197.

Similar proteinsi

Entry informationi

Entry nameiB4DG22_HUMAN
AccessioniPrimary (citable) accession number: B4DG22
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.