B4DFN8 (B4DFN8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ60238, highly similar to Parathyroid hormone receptor EMBL BAG57499.1
Organism	Homo sapiens (Human) EMBL BAG57499.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	439 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity SAAS SAAS017983.

Ontologies

Keywords
Cellular component	Cell membrane SAAS SAAS017983 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS017983
Molecular function	Receptor SAAS SAAS017981 EMBL BAG57499.1
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DFN8 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: D83A15E331461576	FASTA	439	50,021
	10 20 30 40 50 60 MHSLNKTWAN YSDCLRFLQP DISIGKQEFF ERLYVMYTVG YSISFGSLAV AILIIGYFRR 70 80 90 100 110 120 LHCTRNYIHM HLFVSFMLRA TSIFVKDRVV HAHIGVKELE SLIMQDDPQN SIEATSVDKS 130 140 150 160 170 180 QYIGCKIAVV MFIYFLATNY YWILVEGLYL HNLIFVAFFS DTKYLWGFIL IGWGFPAAFV 190 200 210 220 230 240 AAWAVARATL ADARCWELSA GDIKWIYQAP ILAAIGLNFI LFLNTVRVLA TKIWETNAVG 250 260 270 280 290 300 HDTRKQYRKL AKSTLVLVLV FGVHYIVFVC LPHSFTGLGW EIRMHCELFF NSFQGFFVSI 310 320 330 340 350 360 IYCYCNGEVQ AEVKKMWSRW NLSVDWKRTP PCGSRRCGSV LTTVTHSTSS QSQVAASTRM 370 380 390 400 410 420 VLISGKAAKI ASRQPDSHIT LPGYVWSNSE QDCLPHSFHE ETKEDSGRQG DDILMEKPSR 430 PMESNPDTEG CQGETEDVL

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Amygdala EMBL BAG57499.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK294181 mRNA. Translation: BAG57499.1.
IPI	IPI00927172.
UniGene	Hs.570296.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000008248.
HOVERGEN	HBG008318.
OrthoDB	EOG40GCQH.
Gene expression databases
ArrayExpress	B4DFN8.
Bgee	B4DFN8.
Family and domain databases
InterPro	IPR017981. GPCR_2-like. IPR000832. GPCR_2_secretin-like. IPR017983. GPCR_2_secretin-like_CS. [Graphical view]
Pfam	PF00002. 7tm_2. 1 hit. [Graphical view]
PRINTS	PR00249. GPCRSECRETIN.
PROSITE	PS00650. G_PROTEIN_RECEP_F2_2. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35471542.

Entry information

Entry name

B4DFN8_HUMAN

Accession

Primary (citable) accession number: B4DFN8

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 29, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.