B4DF38 (B4DF38_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Platelet-activating factor acetylhydrolase IB subunit alpha Ensembl ENSP00000395628

Submitted name:
cDNA FLJ52123, highly similar to Platelet-activating factor acetylhydrolase IB alpha subunit EMBL BAG57299.1

Gene names

Name:

PAFAH1B1 Ensembl ENSP00000395628

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAG57299.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Cell cycle Cell division Mitosis SAAS SAAS017252 Transport SAAS SAAS017252
Cellular component	Cytoplasm Cytoskeleton SAAS SAAS017252 Microtubule SAAS SAAS017252
Domain	Coiled coil SAAS SAAS017252 Repeat RuleBase RU003532 SAAS SAAS017252 WD repeat RuleBase RU000362 SAAS SAAS017252
Molecular function	Hydrolase EMBL BAG57299.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell division Inferred from electronic annotation. Source: UniProtKB-KW mitosis Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW microtubule Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DF38 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: E161B1FF14C42E18	FASTA	205	23,418
	10 20 30 40 50 60 MTIKLWDFQG FECIRTMHGH DHNVSSVAIM PNGDHIVSAS RDKTIKMWEV QTGYCVKTFT 70 80 90 100 110 120 GHREWVRMVR PNQDGTLIAS CSNDQTVRVW VVATKECKAE LREHEHVVEC ISWAPESSYS 130 140 150 160 170 180 SISEATGSEV GHDNWVRGVL FHSGGKFILS CADDKTLRVW DYKNKRCMKT LNAHEHFVTS 190 200 LDFHKTAPYV VTGSVDQTVK VWECR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C. Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAG57299.1.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC005696 Genomic DNA. No translation available. AC015799 Genomic DNA. No translation available. AK293918 mRNA. Translation: BAG57299.1.
IPI	IPI00909586.
UniGene	Hs.77318.
3D structure databases
SMR	B4DF38. Positions 1-203.
ModBase	Search...
Proteomic databases
PRIDE	B4DF38.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000451360; ENSP00000395628; ENSG00000007168.
UCSC	uc010vqz.2. human.
Organism-specific databases
HGNC	HGNC:8574. PAFAH1B1.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000184015.
HOVERGEN	HBG103859.
Gene expression databases
ArrayExpress	B4DF38.
Family and domain databases
Gene3D	2.130.10.10. 2 hits.
InterPro	IPR017252. Dynein_regulator. IPR020472. G-protein_beta_WD-40_rep. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. [Graphical view]
PANTHER	PTHR22847:SF51. PTHR22847:SF51. 1 hit.
Pfam	PF00400. WD40. 5 hits. [Graphical view]
PRINTS	PR00320. GPROTEINBRPT.
SMART	SM00320. WD40. 4 hits. [Graphical view]
SUPFAM	SSF50978. WD40_like. 1 hit.
PROSITE	PS00678. WD_REPEATS_1. 2 hits. PS50082. WD_REPEATS_2. 4 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	PAFAH1B1. human.
NextBio	35471395.

Entry information

Entry name

B4DF38_HUMAN

Accession

Primary (citable) accession number: B4DF38

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.