B4DER3 (B4DER3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ51757, highly similar to Inositol 1,4,5-trisphosphate receptor type 1 EMBL BAG57174.1
Organism	Homo sapiens (Human) EMBL BAG57174.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1101 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat SAAS SAAS016093
Molecular function	Receptor EMBL BAG57174.1
Gene Ontology (GO)
Biological_process	inositol phosphate-mediated signaling Inferred from electronic annotation. Source: GOC
Cellular_component	endoplasmic reticulum Inferred from electronic annotation. Source: InterPro membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1101	1	EMBL BAG57174.1

Sequences

	Sequence		Length	Mass (Da)
	B4DER3 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 18B3D9F51ABE1DBA	FASTA	1,101	126,200
	10 20 30 40 50 60 MKWSDNKDDI LKGGDVVRLF HAEQEKFLTC DEHRKKQHVF LRTTGRQSAT SATSSKALWE 70 80 90 100 110 120 VEVVQHDPCR GGAGYWNSLF RFKHLATGHY LAAEVDPDFE EECLEFQPSV DPDHDASRSR 130 140 150 160 170 180 LRNAQEKMVY SLVSVPEGND ISSIFELDPT TLRGGDSLVP RNSYVRLRHL CTNTWVHSTN 190 200 210 220 230 240 IPIDKEEEKP VMLKIGTSPV KEDKEAFAIV PVSPAEVRDL DFANDASKVL GSIAGKLEKG 250 260 270 280 290 300 TITQNERRSV TKLLEDLVYF VTGGTNSGQD VLEVVFSKPN RERQKLMREQ NILKQIFKLL 310 320 330 340 350 360 QAPFTDCGDG PMLRLEELGD QRHAPFRHIC RLCYRVLRHS QQDYRKNQEY IAKQFGFMQK 370 380 390 400 410 420 QIGYDVLAED TITALLHNNR KLLEKHITAA EIDTFVSLVR KNREPRFLDY LSDLCVSMNK 430 440 450 460 470 480 SIPVTQELIC KAVLNPTNAD ILIETKLVLS RFEFEGVSST GENALEAGED EEEVWLFWRD 490 500 510 520 530 540 SNKEIRSKSV RELAQDAKEG QKGDRDVLSY YRYQLNLFAR MCLDRQYLAI NEISGQLDVD 550 560 570 580 590 600 LILRCMSDEN LPYDLRASFC RLMLHMHVDR DPQEQVTPVK YARLWSEIPS EIAIDDYDSS 610 620 630 640 650 660 GASKDEIKER FAQTMEFVEE YLRDVVCQRF PFSDKEKNKL TFEVVNLARN LIYFGFYNFS 670 680 690 700 710 720 DLLRLTKILL AILDCVHVTT IFPISKMAKG EENKGSNVMR SIHGVGELMT QVVLRGGGFL 730 740 750 760 770 780 PMTPMAAAPE GNVKQAEPEK EDIMVMDTKL KIIEILQFIL NVRLDYRISC LLCIFKREFD 790 800 810 820 830 840 ESNSQTSETS SGNSSQEGPS NVPGALDFEH IEEQAEGIFG GSEENTPLDL DDHGGRTFLR 850 860 870 880 890 900 VLLHLTMHDY PPLVSGALQL LFRHFSQRQE VLQAFKQVQL LVTSQDVDNY KQIKQDLDQL 910 920 930 940 950 960 RSIVEKSELW VYKGQGPDET MDGASGENEH KKTEEGNNKP QKHESTSSYN YRVVKEILIR 970 980 990 1000 1010 1020 LSKLCVQESA SVRKSRKQQQ RLLRNMGAHA VVLELLQIPY EKAEDTKMQE IMRLAHEFLQ 1030 1040 1050 1060 1070 1080 NFCAGNQQNQ ALLHKHINLF LNPGILEAVT MQHIFMNNFQ LCSEINERVV QHFVHCIETH 1090 1100 GRNVQYIKFL QTIVKAEGKF I

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAG57174.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK293752 mRNA. Translation: BAG57174.1.
IPI	IPI00218659.
RefSeq	NP_001093422.2. NM_001099952.2. NP_001161744.1. NM_001168272.1. NP_002213.5. NM_002222.5.
UniGene	Hs.567295. Hs.715765.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	B4DER3. 1 interaction.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3708.
KEGG	hsa:3708.
Organism-specific databases
CTD	3708.
PharmGKB	PA29978.
Phylogenomic databases
HOGENOM	HOG000007660.
KO	K04958.
OrthoDB	EOG4Z62MP.
Family and domain databases
InterPro	IPR000699. Ca-rel_channel. IPR000493. InsP3_rcpt-bd. IPR016093. MIR_motif. IPR015925. Ryanodine_recept-rel. [Graphical view]
PANTHER	PTHR13715. PTHR13715. 1 hit.
Pfam	PF02815. MIR. 1 hit. PF01365. RYDR_ITPR. 2 hits. [Graphical view]
PRINTS	PR00779. INSP3RECEPTR.
SMART	SM00472. MIR. 2 hits. [Graphical view]
SUPFAM	SSF82109. MIR. 1 hit.
PROSITE	PS50919. MIR. 3 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	3708.
NextBio	14533.

Entry information

Entry name

B4DER3_HUMAN

Accession

Primary (citable) accession number: B4DER3

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.