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B4DER3

- B4DER3_HUMAN

UniProt

B4DER3 - B4DER3_HUMAN

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Protein
Submitted name:

cDNA FLJ51757, highly similar to Inositol 1,4,5-trisphosphate receptor type 1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51757, highly similar to Inositol 1,4,5-trisphosphate receptor type 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: InterPro
  2. membrane Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29978.

PTM / Processingi

Proteomic databases

PRIDEiB4DER3.

Interactioni

Protein-protein interaction databases

IntActiB4DER3. 1 interaction.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000007660.
KOiK04958.

Family and domain databases

Gene3Di1.25.10.30. 2 hits.
InterProiIPR000493. InsP3_rcpt-bd.
IPR016093. MIR_motif.
IPR000699. RIH_dom.
IPR015925. Ryanodine_recept-rel.
[Graphical view]
PANTHERiPTHR13715. PTHR13715. 1 hit.
PfamiPF02815. MIR. 1 hit.
PF01365. RYDR_ITPR. 2 hits.
[Graphical view]
PRINTSiPR00779. INSP3RECEPTR.
SMARTiSM00472. MIR. 2 hits.
[Graphical view]
SUPFAMiSSF100909. SSF100909. 2 hits.
SSF82109. SSF82109. 1 hit.
PROSITEiPS50919. MIR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B4DER3-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MKWSDNKDDI LKGGDVVRLF HAEQEKFLTC DEHRKKQHVF LRTTGRQSAT
60 70 80 90 100
SATSSKALWE VEVVQHDPCR GGAGYWNSLF RFKHLATGHY LAAEVDPDFE
110 120 130 140 150
EECLEFQPSV DPDHDASRSR LRNAQEKMVY SLVSVPEGND ISSIFELDPT
160 170 180 190 200
TLRGGDSLVP RNSYVRLRHL CTNTWVHSTN IPIDKEEEKP VMLKIGTSPV
210 220 230 240 250
KEDKEAFAIV PVSPAEVRDL DFANDASKVL GSIAGKLEKG TITQNERRSV
260 270 280 290 300
TKLLEDLVYF VTGGTNSGQD VLEVVFSKPN RERQKLMREQ NILKQIFKLL
310 320 330 340 350
QAPFTDCGDG PMLRLEELGD QRHAPFRHIC RLCYRVLRHS QQDYRKNQEY
360 370 380 390 400
IAKQFGFMQK QIGYDVLAED TITALLHNNR KLLEKHITAA EIDTFVSLVR
410 420 430 440 450
KNREPRFLDY LSDLCVSMNK SIPVTQELIC KAVLNPTNAD ILIETKLVLS
460 470 480 490 500
RFEFEGVSST GENALEAGED EEEVWLFWRD SNKEIRSKSV RELAQDAKEG
510 520 530 540 550
QKGDRDVLSY YRYQLNLFAR MCLDRQYLAI NEISGQLDVD LILRCMSDEN
560 570 580 590 600
LPYDLRASFC RLMLHMHVDR DPQEQVTPVK YARLWSEIPS EIAIDDYDSS
610 620 630 640 650
GASKDEIKER FAQTMEFVEE YLRDVVCQRF PFSDKEKNKL TFEVVNLARN
660 670 680 690 700
LIYFGFYNFS DLLRLTKILL AILDCVHVTT IFPISKMAKG EENKGSNVMR
710 720 730 740 750
SIHGVGELMT QVVLRGGGFL PMTPMAAAPE GNVKQAEPEK EDIMVMDTKL
760 770 780 790 800
KIIEILQFIL NVRLDYRISC LLCIFKREFD ESNSQTSETS SGNSSQEGPS
810 820 830 840 850
NVPGALDFEH IEEQAEGIFG GSEENTPLDL DDHGGRTFLR VLLHLTMHDY
860 870 880 890 900
PPLVSGALQL LFRHFSQRQE VLQAFKQVQL LVTSQDVDNY KQIKQDLDQL
910 920 930 940 950
RSIVEKSELW VYKGQGPDET MDGASGENEH KKTEEGNNKP QKHESTSSYN
960 970 980 990 1000
YRVVKEILIR LSKLCVQESA SVRKSRKQQQ RLLRNMGAHA VVLELLQIPY
1010 1020 1030 1040 1050
EKAEDTKMQE IMRLAHEFLQ NFCAGNQQNQ ALLHKHINLF LNPGILEAVT
1060 1070 1080 1090 1100
MQHIFMNNFQ LCSEINERVV QHFVHCIETH GRNVQYIKFL QTIVKAEGKF

I
Length:1,101
Mass (Da):126,200
Last modified:September 23, 2008 - v1
Checksum:i18B3D9F51ABE1DBA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1101 – 11011Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293752 mRNA. Translation: BAG57174.1.
RefSeqiNP_001093422.2. NM_001099952.2.
NP_001161744.1. NM_001168272.1.
NP_002213.5. NM_002222.5.
UniGeneiHs.567295.
Hs.715765.

Genome annotation databases

GeneIDi3708.
KEGGihsa:3708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293752 mRNA. Translation: BAG57174.1 .
RefSeqi NP_001093422.2. NM_001099952.2.
NP_001161744.1. NM_001168272.1.
NP_002213.5. NM_002222.5.
UniGenei Hs.567295.
Hs.715765.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi B4DER3. 1 interaction.

Proteomic databases

PRIDEi B4DER3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3708.
KEGGi hsa:3708.

Organism-specific databases

CTDi 3708.
PharmGKBi PA29978.

Phylogenomic databases

HOGENOMi HOG000007660.
KOi K04958.

Miscellaneous databases

GenomeRNAii 3708.
NextBioi 14533.

Family and domain databases

Gene3Di 1.25.10.30. 2 hits.
InterProi IPR000493. InsP3_rcpt-bd.
IPR016093. MIR_motif.
IPR000699. RIH_dom.
IPR015925. Ryanodine_recept-rel.
[Graphical view ]
PANTHERi PTHR13715. PTHR13715. 1 hit.
Pfami PF02815. MIR. 1 hit.
PF01365. RYDR_ITPR. 2 hits.
[Graphical view ]
PRINTSi PR00779. INSP3RECEPTR.
SMARTi SM00472. MIR. 2 hits.
[Graphical view ]
SUPFAMi SSF100909. SSF100909. 2 hits.
SSF82109. SSF82109. 1 hit.
PROSITEi PS50919. MIR. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: CerebellumImported.

Entry informationi

Entry nameiB4DER3_HUMAN
AccessioniPrimary (citable) accession number: B4DER3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.