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B4DER3

- B4DER3_HUMAN

UniProt

B4DER3 - B4DER3_HUMAN

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Protein
Submitted name: cDNA FLJ51757, highly similar to Inositol 1,4,5-trisphosphate receptor type 1
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51757, highly similar to Inositol 1,4,5-trisphosphate receptor type 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: InterPro
  2. membrane Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29978.

PTM / Processingi

Proteomic databases

PRIDEiB4DER3.

Interactioni

Protein-protein interaction databases

IntActiB4DER3. 1 interaction.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000007660.
KOiK04958.

Family and domain databases

Gene3Di1.25.10.30. 2 hits.
InterProiIPR000493. InsP3_rcpt-bd.
IPR016093. MIR_motif.
IPR000699. RIH_dom.
IPR015925. Ryanodine_recept-rel.
[Graphical view]
PANTHERiPTHR13715. PTHR13715. 1 hit.
PfamiPF02815. MIR. 1 hit.
PF01365. RYDR_ITPR. 2 hits.
[Graphical view]
PRINTSiPR00779. INSP3RECEPTR.
SMARTiSM00472. MIR. 2 hits.
[Graphical view]
SUPFAMiSSF100909. SSF100909. 2 hits.
SSF82109. SSF82109. 1 hit.
PROSITEiPS50919. MIR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B4DER3-1 [UniParc]FASTAAdd to Basket

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MKWSDNKDDI LKGGDVVRLF HAEQEKFLTC DEHRKKQHVF LRTTGRQSAT     50
SATSSKALWE VEVVQHDPCR GGAGYWNSLF RFKHLATGHY LAAEVDPDFE 100
EECLEFQPSV DPDHDASRSR LRNAQEKMVY SLVSVPEGND ISSIFELDPT 150
TLRGGDSLVP RNSYVRLRHL CTNTWVHSTN IPIDKEEEKP VMLKIGTSPV 200
KEDKEAFAIV PVSPAEVRDL DFANDASKVL GSIAGKLEKG TITQNERRSV 250
TKLLEDLVYF VTGGTNSGQD VLEVVFSKPN RERQKLMREQ NILKQIFKLL 300
QAPFTDCGDG PMLRLEELGD QRHAPFRHIC RLCYRVLRHS QQDYRKNQEY 350
IAKQFGFMQK QIGYDVLAED TITALLHNNR KLLEKHITAA EIDTFVSLVR 400
KNREPRFLDY LSDLCVSMNK SIPVTQELIC KAVLNPTNAD ILIETKLVLS 450
RFEFEGVSST GENALEAGED EEEVWLFWRD SNKEIRSKSV RELAQDAKEG 500
QKGDRDVLSY YRYQLNLFAR MCLDRQYLAI NEISGQLDVD LILRCMSDEN 550
LPYDLRASFC RLMLHMHVDR DPQEQVTPVK YARLWSEIPS EIAIDDYDSS 600
GASKDEIKER FAQTMEFVEE YLRDVVCQRF PFSDKEKNKL TFEVVNLARN 650
LIYFGFYNFS DLLRLTKILL AILDCVHVTT IFPISKMAKG EENKGSNVMR 700
SIHGVGELMT QVVLRGGGFL PMTPMAAAPE GNVKQAEPEK EDIMVMDTKL 750
KIIEILQFIL NVRLDYRISC LLCIFKREFD ESNSQTSETS SGNSSQEGPS 800
NVPGALDFEH IEEQAEGIFG GSEENTPLDL DDHGGRTFLR VLLHLTMHDY 850
PPLVSGALQL LFRHFSQRQE VLQAFKQVQL LVTSQDVDNY KQIKQDLDQL 900
RSIVEKSELW VYKGQGPDET MDGASGENEH KKTEEGNNKP QKHESTSSYN 950
YRVVKEILIR LSKLCVQESA SVRKSRKQQQ RLLRNMGAHA VVLELLQIPY 1000
EKAEDTKMQE IMRLAHEFLQ NFCAGNQQNQ ALLHKHINLF LNPGILEAVT 1050
MQHIFMNNFQ LCSEINERVV QHFVHCIETH GRNVQYIKFL QTIVKAEGKF 1100
I 1101
Length:1,101
Mass (Da):126,200
Last modified:September 23, 2008 - v1
Checksum:i18B3D9F51ABE1DBA
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1101 – 11011Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK293752 mRNA. Translation: BAG57174.1.
RefSeqiNP_001093422.2. NM_001099952.2.
NP_001161744.1. NM_001168272.1.
NP_002213.5. NM_002222.5.
UniGeneiHs.567295.
Hs.715765.

Genome annotation databases

GeneIDi3708.
KEGGihsa:3708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK293752 mRNA. Translation: BAG57174.1 .
RefSeqi NP_001093422.2. NM_001099952.2.
NP_001161744.1. NM_001168272.1.
NP_002213.5. NM_002222.5.
UniGenei Hs.567295.
Hs.715765.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi B4DER3. 1 interaction.

Proteomic databases

PRIDEi B4DER3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3708.
KEGGi hsa:3708.

Organism-specific databases

CTDi 3708.
PharmGKBi PA29978.

Phylogenomic databases

HOGENOMi HOG000007660.
KOi K04958.

Miscellaneous databases

GenomeRNAii 3708.
NextBioi 14533.

Family and domain databases

Gene3Di 1.25.10.30. 2 hits.
InterProi IPR000493. InsP3_rcpt-bd.
IPR016093. MIR_motif.
IPR000699. RIH_dom.
IPR015925. Ryanodine_recept-rel.
[Graphical view ]
PANTHERi PTHR13715. PTHR13715. 1 hit.
Pfami PF02815. MIR. 1 hit.
PF01365. RYDR_ITPR. 2 hits.
[Graphical view ]
PRINTSi PR00779. INSP3RECEPTR.
SMARTi SM00472. MIR. 2 hits.
[Graphical view ]
SUPFAMi SSF100909. SSF100909. 2 hits.
SSF82109. SSF82109. 1 hit.
PROSITEi PS50919. MIR. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: CerebellumImported.

Entry informationi

Entry nameiB4DER3_HUMAN
AccessioniPrimary (citable) accession number: B4DER3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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