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Protein
Submitted name:

cDNA FLJ56959, highly similar to Vascular endothelial growth factor receptor 2 (EC 2.7.10.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. vascular endothelial growth factor-activated receptor activity Source: Ensembl

GO - Biological processi

  1. branching morphogenesis of an epithelial tube Source: Ensembl
  2. calcium ion homeostasis Source: Ensembl
  3. cell fate commitment Source: Ensembl
  4. cell maturation Source: Ensembl
  5. cell migration Source: Ensembl
  6. endothelial cell differentiation Source: Ensembl
  7. hemopoiesis Source: Ensembl
  8. lung alveolus development Source: Ensembl
  9. lymph vessel development Source: Ensembl
  10. ovarian follicle development Source: Ensembl
  11. positive regulation of epithelial cell proliferation Source: Ensembl
  12. positive regulation of mesenchymal cell proliferation Source: Ensembl
  13. surfactant homeostasis Source: Ensembl
  14. vascular endothelial growth factor receptor signaling pathway Source: Ensembl
  15. vasculogenesis Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56959, highly similar to Vascular endothelial growth factor receptor 2 (EC 2.7.10.1)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. external side of plasma membrane Source: Ensembl
  2. integral component of membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB4DEK3.
ExpressionAtlasiB4DEK3. baseline and differential.

Interactioni

Family & Domainsi

Family and domain databases

InterProiIPR009136. VEGFR2_rcpt.
[Graphical view]
PANTHERiPTHR24416:SF45. PTHR24416:SF45. 1 hit.
PRINTSiPR01834. VEGFRECEPTR2.

Sequencei

Sequence statusi: Complete.

B4DEK3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEEDSGLSLP TSPVSCMEEE EVCDPKFHYD NTAGISQYLQ NSKRKSRPVS
60 70 80 90 100
VKTFEDIPLE EPEVKVIPDD NQTDSGMVLA SEELKTLEDR TKLSPSFGGM
110 120 130 140 150
VPSKSRESVA SEGSNQTSGY QSGYHSDDTD TTVYSSEEAE LLKLIEIGVQ
160 170
TGSTAQILQP DSGTTLSSPP V
Length:171
Mass (Da):18,542
Last modified:September 23, 2008 - v1
Checksum:iD11464E74163979E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293668 mRNA. Translation: BAG57114.1.
UniGeneiHs.479756.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293668 mRNA. Translation: BAG57114.1.
UniGeneiHs.479756.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiB4DEK3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

NextBioi35471242.

Gene expression databases

BgeeiB4DEK3.
ExpressionAtlasiB4DEK3. baseline and differential.

Family and domain databases

InterProiIPR009136. VEGFR2_rcpt.
[Graphical view]
PANTHERiPTHR24416:SF45. PTHR24416:SF45. 1 hit.
PRINTSiPR01834. VEGFRECEPTR2.
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: CerebellumImported.

Entry informationi

Entry nameiB4DEK3_HUMAN
AccessioniPrimary (citable) accession number: B4DEK3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.