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Protein
Submitted name:

cDNA FLJ56323, highly similar to Methylated-DNA--protein-cysteinemethyltransferase (EC 2.1.1.63)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56323, highly similar to Methylated-DNA--protein-cysteinemethyltransferase (EC 2.1.1.63)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA239.

PTM / Processingi

Proteomic databases

MaxQBiB4DEE8.
PaxDbiB4DEE8.
PeptideAtlasiB4DEE8.
PRIDEiB4DEE8.

PTM databases

iPTMnetiB4DEE8.

Expressioni

Gene expression databases

BgeeiB4DEE8.
ExpressionAtlasiB4DEE8. baseline and differential.
GenevisibleiB4DEE8. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000302111.

Structurei

3D structure databases

ProteinModelPortaliB4DEE8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 12185Methyltransf_1NInterPro annotationAdd
BLAST
Domaini126 – 20479DNA_binding_1InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG4062. Eukaryota.
COG0350. LUCA.
GeneTreeiENSGT00390000015799.
HOGENOMiHOG000244137.
HOVERGENiHBG001146.
KOiK00567.
OMAiFKEATQW.
PhylomeDBiB4DEE8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001497. MethylDNA_cys_MeTrfase_AS.
IPR014048. MethylDNA_cys_MeTrfase_DNA-bd.
IPR008332. MethylG_MeTrfase_N.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01035. DNA_binding_1. 1 hit.
PF02870. Methyltransf_1N. 1 hit.
[Graphical view]
SUPFAMiSSF46767. SSF46767. 1 hit.
SSF53155. SSF53155. 1 hit.
TIGRFAMsiTIGR00589. ogt. 1 hit.
PROSITEiPS00374. MGMT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DEE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGQPAPLER FASRRPQVLA VRTVCDLVLG KMDKDCEMKR TTLDSPLGKL
60 70 80 90 100
ELSGCEQGLH EIKLLGKGTS AADAVEVPAP AAVLGGPEPL MQCTAWLNAY
110 120 130 140 150
FHQPEAIEEF PVPALHHPVF QQESFTRQVL WKLLKVVKFG EVISYQQLAA
160 170 180 190 200
LAGNPKAARA VGGAMRGNPV PILIPCHRVV CSSGAVGNYS GGLAVKEWLL
210 220 230
AHEGHRLGKP GLGGSSGLAG AWLKGAGATS GSPPAGRN
Length:238
Mass (Da):25,050
Last modified:September 23, 2008 - v1
Checksum:i9A1774B6637A0788
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293593 mRNA. Translation: BAG57059.1.
RefSeqiNP_002403.2. NM_002412.4.
UniGeneiHs.501522.

Genome annotation databases

GeneIDi4255.
KEGGihsa:4255.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293593 mRNA. Translation: BAG57059.1.
RefSeqiNP_002403.2. NM_002412.4.
UniGeneiHs.501522.

3D structure databases

ProteinModelPortaliB4DEE8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000302111.

PTM databases

iPTMnetiB4DEE8.

Proteomic databases

MaxQBiB4DEE8.
PaxDbiB4DEE8.
PeptideAtlasiB4DEE8.
PRIDEiB4DEE8.

Protocols and materials databases

DNASUi4255.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4255.
KEGGihsa:4255.

Organism-specific databases

CTDi4255.
PharmGKBiPA239.

Phylogenomic databases

eggNOGiKOG4062. Eukaryota.
COG0350. LUCA.
GeneTreeiENSGT00390000015799.
HOGENOMiHOG000244137.
HOVERGENiHBG001146.
KOiK00567.
OMAiFKEATQW.
PhylomeDBiB4DEE8.

Miscellaneous databases

GenomeRNAii4255.

Gene expression databases

BgeeiB4DEE8.
ExpressionAtlasiB4DEE8. baseline and differential.
GenevisibleiB4DEE8. HS.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001497. MethylDNA_cys_MeTrfase_AS.
IPR014048. MethylDNA_cys_MeTrfase_DNA-bd.
IPR008332. MethylG_MeTrfase_N.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01035. DNA_binding_1. 1 hit.
PF02870. Methyltransf_1N. 1 hit.
[Graphical view]
SUPFAMiSSF46767. SSF46767. 1 hit.
SSF53155. SSF53155. 1 hit.
TIGRFAMsiTIGR00589. ogt. 1 hit.
PROSITEiPS00374. MGMT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: CerebellumImported.

Entry informationi

Entry nameiB4DEE8_HUMAN
AccessioniPrimary (citable) accession number: B4DEE8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 6, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.