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UniProtKB - B4DDV3 (B4DDV3_HUMAN)

UniProt

B4DDV3 - B4DDV3_HUMAN

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Protein
Submitted name:

cDNA FLJ52470, highly similar to Mono-ADP-ribosyltransferase sirtuin-6 (EC 2.4.2.31)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Enzyme and pathway databases

SignaLinkiB4DDV3.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52470, highly similar to Mono-ADP-ribosyltransferase sirtuin-6 (EC 2.4.2.31)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

PTM / Processingi

Proteomic databases

PaxDbiB4DDV3.
PeptideAtlasiB4DDV3.

Expressioni

Gene expression databases

BgeeiENSG00000077463.

Interactioni

Protein-protein interaction databases

IntActiB4DDV3. 12 interactions.
STRINGi9606.ENSP00000337332.

Structurei

3D structure databases

ProteinModelPortaliB4DDV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 202202Deacetylase sirtuin-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1905. Eukaryota.
COG0846. LUCA.
HOVERGENiHBG060028.

Family and domain databases

Gene3Di3.40.50.1220. 2 hits.
InterProiIPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view]
PANTHERiPTHR11085. PTHR11085. 1 hit.
PfamiPF02146. SIR2. 1 hit.
[Graphical view]
SUPFAMiSSF52467. SSF52467. 1 hit.
PROSITEiPS50305. SIRTUIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DDV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEERGLAPKF DTTFESARPT QTHMALVQLE RVGLLRFLVS QNVDGLHVRS 
        60         70         80         90        100
GFPRDKLAEL HGNMFVEECA KCKTQYVRDT VVGTMGLKAT GRLCTVAKAR 
       110        120        130        140        150
GLRACRGELR DTILDWEDSL PDRDLALADE ASRNADLSIT LGTSLQIRPS 
       160        170        180        190        200
GNLPLATKRR GGRLVIVNLQ PTKHDRHADL RIHGYVDEVM TRLMKHLGLE 
       210        220        230        240        250
IPAWDGPRVL ERALPPLPRP PTPKLEPKEE SPTRINGSIP AGPKQEPCAQ 
       260        270        280 
HNGSEPASPK RERPTSPAPH RPPKRVKAKA VPS
Length:283
Mass (Da):31,319
Last modified:September 23, 2008 - v1
Checksum:i775740F80DA0ACE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293348 mRNA. Translation: BAG56864.1.
RefSeqiNP_001307987.1. NM_001321058.1.
UniGeneiHs.423756.

Genome annotation databases

GeneIDi51548.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293348 mRNA. Translation: BAG56864.1.
RefSeqiNP_001307987.1. NM_001321058.1.
UniGeneiHs.423756.

3D structure databases

ProteinModelPortaliB4DDV3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB4DDV3. 12 interactions.
STRINGi9606.ENSP00000337332.

Proteomic databases

PaxDbiB4DDV3.
PeptideAtlasiB4DDV3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi51548.

Organism-specific databases

CTDi51548.

Phylogenomic databases

eggNOGiKOG1905. Eukaryota.
COG0846. LUCA.
HOVERGENiHBG060028.

Enzyme and pathway databases

SignaLinkiB4DDV3.

Miscellaneous databases

ChiTaRSiSIRT6. human.
GenomeRNAii51548.

Gene expression databases

BgeeiENSG00000077463.

Family and domain databases

Gene3Di3.40.50.1220. 2 hits.
InterProiIPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026590. Ssirtuin_cat_dom.
[Graphical view]
PANTHERiPTHR11085. PTHR11085. 1 hit.
PfamiPF02146. SIR2. 1 hit.
[Graphical view]
SUPFAMiSSF52467. SSF52467. 1 hit.
PROSITEiPS50305. SIRTUIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DDV3_HUMAN
AccessioniPrimary (citable) accession number: B4DDV3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.