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Protein
Submitted name:

Dynamin-1-like protein

Gene

DNM1L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Dynamin-1-like proteinImported
Submitted name:
cDNA FLJ59840, highly similar to Dynamin-1-like protein (EC 3.6.5.5)Imported
Gene namesi
Name:DNM1LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000087470.17
HGNCiHGNC:2973 DNM1L

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087470

PTM / Processingi

Proteomic databases

MaxQBiB4DDQ3
PeptideAtlasiB4DDQ3
PRIDEiB4DDQ3

Expressioni

Gene expression databases

BgeeiENSG00000087470
ExpressionAtlasiB4DDQ3 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 180Dynamin-type GInterPro annotationAdd BLAST159

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili97 – 117Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00910000144225
HOGENOMiHOG000069872
HOVERGENiHBG103067

Family and domain databases

CDDicd08771 DLP_1, 1 hit
InterProiView protein in InterPro
IPR030556 DNM1L
IPR001401 Dynamin_GTPase
IPR019762 Dynamin_GTPase_CS
IPR022812 Dynamin_SF
IPR030381 G_DYNAMIN_dom
IPR027417 P-loop_NTPase
PANTHERiPTHR11566 PTHR11566, 2 hits
PTHR11566:SF39 PTHR11566:SF39, 2 hits
PfamiView protein in Pfam
PF00350 Dynamin_N, 1 hit
PRINTSiPR00195 DYNAMIN
SMARTiView protein in SMART
SM00053 DYNc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00410 G_DYNAMIN_1, 1 hit
PS51718 G_DYNAMIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

B4DDQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL
60 70 80 90 100
LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL
110 120 130 140 150
YTDFDEIRQE IENETERISG NNKVPVGDQP KDIELQIREL ILRFISNPNS
160 170 180
IILAVTAANT DMATSEALKI SREVDPDGAS
Length:180
Mass (Da):19,885
Last modified:September 23, 2008 - v1
Checksum:i7AAEBB0EB83E8635
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084824 Genomic DNA No translation available.
AC087588 Genomic DNA No translation available.
AK293290 mRNA Translation: BAG56814.1
UniGeneiHs.556296

Genome annotation databases

EnsembliENST00000413295; ENSP00000396030; ENSG00000087470
UCSCiuc058mpb.1 human

Similar proteinsi

Entry informationi

Entry nameiB4DDQ3_HUMAN
AccessioniPrimary (citable) accession number: B4DDQ3
Secondary accession number(s): E7EWQ6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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