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Protein
Submitted name:

Dynamin-1-like protein

Gene

DNM1L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Dynamin-1-like proteinImported
Submitted name:
cDNA FLJ59840, highly similar to Dynamin-1-like protein (EC 3.6.5.5)Imported
Gene namesi
Name:DNM1LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:2973. DNM1L.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087470.

Expressioni

Gene expression databases

BgeeiENSG00000087470.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 180Dynamin-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST159

Sequence similaritiesi

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119213.
HOGENOMiHOG000069872.
HOVERGENiHBG103067.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiView protein in InterPro
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR027417. P-loop_NTPase.
PANTHERiPTHR11566. PTHR11566. 1 hit.
PfamiView protein in Pfam
PF00350. Dynamin_N. 1 hit.
PRINTSiPR00195. DYNAMIN.
SMARTiView protein in SMART
SM00053. DYNc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DDQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL
60 70 80 90 100
LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL
110 120 130 140 150
YTDFDEIRQE IENETERISG NNKVPVGDQP KDIELQIREL ILRFISNPNS
160 170 180
IILAVTAANT DMATSEALKI SREVDPDGAS
Length:180
Mass (Da):19,885
Last modified:September 23, 2008 - v1
Checksum:i7AAEBB0EB83E8635
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084824 Genomic DNA. No translation available.
AC087588 Genomic DNA. No translation available.
AK293290 mRNA. Translation: BAG56814.1.
UniGeneiHs.556296.

Genome annotation databases

EnsembliENST00000413295; ENSP00000396030; ENSG00000087470.
UCSCiuc058mpb.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084824 Genomic DNA. No translation available.
AC087588 Genomic DNA. No translation available.
AK293290 mRNA. Translation: BAG56814.1.
UniGeneiHs.556296.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413295; ENSP00000396030; ENSG00000087470.
UCSCiuc058mpb.1. human.

Organism-specific databases

HGNCiHGNC:2973. DNM1L.
OpenTargetsiENSG00000087470.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119213.
HOGENOMiHOG000069872.
HOVERGENiHBG103067.

Miscellaneous databases

ChiTaRSiDNM1L. human.

Gene expression databases

BgeeiENSG00000087470.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiView protein in InterPro
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR027417. P-loop_NTPase.
PANTHERiPTHR11566. PTHR11566. 1 hit.
PfamiView protein in Pfam
PF00350. Dynamin_N. 1 hit.
PRINTSiPR00195. DYNAMIN.
SMARTiView protein in SMART
SM00053. DYNc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB4DDQ3_HUMAN
AccessioniPrimary (citable) accession number: B4DDQ3
Secondary accession number(s): E7EWQ6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: February 15, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.