B4DDN2 (B4DDN2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Serine/threonine-protein kinase Nek11 Ensembl ENSP00000411888

Submitted name:
cDNA FLJ60411, highly similar to Serine/threonine-protein kinase Nek11 (EC2.7.11.1) EMBL BAG56793.1

Gene names

Name:

NEK11 Ensembl ENSP00000411888

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAG56793.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Kinase EMBL BAG56793.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	nucleus Inferred from direct assay. Source: HPA
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein serine/threonine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DDN2 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: BBC73A23BCA8FE78	FASTA	461	53,164
	10 20 30 40 50 60 MHERRILHRD LKSKNVFLKN NLLKIGDFGV SRLLMGSCDL ATTLTGTPHY MSPEALKHQG 70 80 90 100 110 120 YDTKSDIWSL ACILYEMCCM NHAFAGSNFL SIVLKIVEGD TPSLPERYPK ELNAIMESML 130 140 150 160 170 180 NKNPSLRPSA IEILKIPYLD EQLQNLMCRY SEMTLEDKNL DCQKEAAHII NAMQKRIHLQ 190 200 210 220 230 240 TLRALSEVQK MTPRERMRLR KLQAADEKAR KLKKIVEEKY EENSKRMQEL RSRNFQQLSV 250 260 270 280 290 300 DVLHESDEPT LENLPESQPI PSMDLHELES IVEDATSDLG YHEIPEDPLV AEEYYADAFD 310 320 330 340 350 360 SYCEESDEEE EEIALERPEK EIRNEGSQPA YRTNQQDSDI EALARCLENV LGCTSLDTKT 370 380 390 400 410 420 ITTMAEDMSP GPPIFNSVMA RTKMKRMRES AMQKLGTEVF EEVYNYLKRA RHQNASEAEI 430 440 450 460 RECLEKVVPQ ASDCFEVDQL LYFEEQLLIT MGKEPTLQNH L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC010210 Genomic DNA. No translation available. AC055733 Genomic DNA. No translation available. AC083908 Genomic DNA. No translation available. AC116424 Genomic DNA. No translation available. AC121332 Genomic DNA. No translation available. AK293261 mRNA. Translation: BAG56793.1.
IPI	IPI00788917.
UniGene	Hs.657336.
3D structure databases
SMR	B4DDN2. Positions 2-165.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000412440; ENSP00000411888; ENSG00000114670.
UCSC	uc011blk.2. human.
Organism-specific databases
HGNC	HGNC:18593. NEK11.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000293260.
HOVERGEN	HBG082016.
Gene expression databases
ArrayExpress	B4DDN2.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35470981.

Entry information

Entry name

B4DDN2_HUMAN

Accession

Primary (citable) accession number: B4DDN2

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.