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B4DDN2 (B4DDN2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

cDNA FLJ60411, highly similar to Serine/threonine-protein kinase Nek11 (EC2.7.11.1) EMBL BAG56793.1
Gene names
Name:NEK11 Ensembl ENSP00000411888
OrganismHomo sapiens (Human) [Reference proteome] EMBL BAG56793.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length461 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Molecular functionKinase EMBL BAG56793.1
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from direct assay. Source: HPA

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

protein serine/threonine kinase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B4DDN2 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: BBC73A23BCA8FE78

FASTA46153,164
        10         20         30         40         50         60 
MHERRILHRD LKSKNVFLKN NLLKIGDFGV SRLLMGSCDL ATTLTGTPHY MSPEALKHQG 

        70         80         90        100        110        120 
YDTKSDIWSL ACILYEMCCM NHAFAGSNFL SIVLKIVEGD TPSLPERYPK ELNAIMESML 

       130        140        150        160        170        180 
NKNPSLRPSA IEILKIPYLD EQLQNLMCRY SEMTLEDKNL DCQKEAAHII NAMQKRIHLQ 

       190        200        210        220        230        240 
TLRALSEVQK MTPRERMRLR KLQAADEKAR KLKKIVEEKY EENSKRMQEL RSRNFQQLSV 

       250        260        270        280        290        300 
DVLHESDEPT LENLPESQPI PSMDLHELES IVEDATSDLG YHEIPEDPLV AEEYYADAFD 

       310        320        330        340        350        360 
SYCEESDEEE EEIALERPEK EIRNEGSQPA YRTNQQDSDI EALARCLENV LGCTSLDTKT 

       370        380        390        400        410        420 
ITTMAEDMSP GPPIFNSVMA RTKMKRMRES AMQKLGTEVF EEVYNYLKRA RHQNASEAEI 

       430        440        450        460 
RECLEKVVPQ ASDCFEVDQL LYFEEQLLIT MGKEPTLQNH L 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. expand/collapse author list , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"NEDO human cDNA sequencing project focused on splicing variants."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC010210 Genomic DNA. No translation available.
AC055733 Genomic DNA. No translation available.
AC083908 Genomic DNA. No translation available.
AC116424 Genomic DNA. No translation available.
AC121332 Genomic DNA. No translation available.
AK293261 mRNA. Translation: BAG56793.1.
UniGeneHs.657336.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000412440; ENSP00000411888; ENSG00000114670.
UCSCuc011blk.2. human.

Organism-specific databases

HGNCHGNC:18593. NEK11.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHOG000293260.
HOVERGENHBG082016.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35470981.

Entry information

Entry nameB4DDN2_HUMAN
AccessionPrimary (citable) accession number: B4DDN2
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.