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Protein
Submitted name:

cDNA FLJ59455, highly similar to Homo sapiens neuronal guanine nucleotide exchange factor (NGEF), mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ59455, highly similar to Homo sapiens neuronal guanine nucleotide exchange factor (NGEF), mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

MaxQBiB4DDI2.
PaxDbiB4DDI2.
PeptideAtlasiB4DDI2.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB4DDI2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 180DHInterPro annotationAdd BLAST180
Domaini212 – 324PHInterPro annotationAdd BLAST113
Domaini335 – 396SH3InterPro annotationAdd BLAST62

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3523. Eukaryota.
COG5422. LUCA.
HOVERGENiHBG058673.

Family and domain databases

CDDicd00160. RhoGEF. 1 hit.
cd11939. SH3_ephexin1. 1 hit.
Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR035899. DBL_dom_sf.
IPR000219. DH-domain.
IPR035635. Ephexin-1_SH3.
IPR011993. PH-like_dom_sf.
IPR001849. PH_domain.
IPR036028. SH3-like_dom_sf.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF00018. SH3_1. 1 hit.
SMARTiView protein in SMART
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
SSF50729. SSF50729. 1 hit.
PROSITEiView protein in PROSITE
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DDI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFELVTSEAS YYKSLNLLVS HFMENERIRK ILHPSEAHIL FSNVLDVLAV
60 70 80 90 100
SERFLLELEH RMEENIVISD VCDIVYRYAA DHFSVYITYV SNQTYQERTY
110 120 130 140 150
KQLLQEKAAF RELIAQLELD PKCRGLPFSS FLILPFQRIT RLKLLVQNIL
160 170 180 190 200
KRVEERSERE CTALDAHKEL EMVVKACNEG VRKMSRTEQM ISIQKKMEFK
210 220 230 240 250
IKSVPIISHS RWLLKQGELQ QMSGPKTSRT LRTKKLFHEI YLFLFNDLLV
260 270 280 290 300
ICRQIPGDKY QVFDSAPRGL LRVEELEDQG QTLANVFILR LLENADDREA
310 320 330 340 350
TYMLKASSQS EMKRWMTSLA PNRRTKFVSF TSRLLDCPQV QCVHPYVAQQ
360 370 380 390 400
PDELTLELAD ILNILDKTDD GWIFGERLHD QERGWFPSSM TEEILNPKIR
410 420 430
SQNLKECFRV HKMDDPQRSQ NKDRRKLGSR NRQ
Length:433
Mass (Da):50,970
Last modified:September 23, 2008 - v1
Checksum:i355240E0DE0E69DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293203 mRNA. Translation: BAG56743.1.
RefSeqiXP_011509226.1. XM_011510924.1.
XP_011509227.1. XM_011510925.1.
UniGeneiHs.97316.

Genome annotation databases

GeneIDi25791.

Similar proteinsi

Entry informationi

Entry nameiB4DDI2_HUMAN
AccessioniPrimary (citable) accession number: B4DDI2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 22, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.