B4DDF8 (B4DDF8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ51786, highly similar to Retinal dehydrogenase 1 (EC 1.2.1.36) EMBL BAG56719.1
Organism	Homo sapiens (Human) EMBL BAG56719.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	422 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344
Gene Ontology (GO)
Molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DDF8 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: F8CF0A555F2368AE	FASTA	422	45,997
	10 20 30 40 50 60 MDASERGRLL YKLADLIERD RLLLATMESM NGGKLYSNAY LNDLAGCIKT LRYCAGWADK 70 80 90 100 110 120 IQGRTIPIDG NFFTYTRHEP IGVCGQIIPW NFPLVMLIWK IGPALSCGNT VVVKPAEQTP 130 140 150 160 170 180 LTALHVASLI KEAGFPPGVV NIVPGYGPTA GAAISSHMDI DKVAFTGSTE VGKLIKEAAG 190 200 210 220 230 240 KSNLKRVTLE LGGKSPCIVL ADADLDNAVE FAHHGVFYHQ GQCCIAASRI FVEESIYDEF 250 260 270 280 290 300 VRRSVERAKK YILGNPLTPG VTQGPQIDKE QYDKILDLIE SGKKEGAKLE CGGGPWGNKG 310 320 330 340 350 360 YFVQPTVFSN VTDEMRIAKE EIFGPVQQIM KFKSLDDVIK RANNTFYGLS AGVFTKDIDK 370 380 390 400 410 420 AITISSALQA GTVWVNCYGV VSAQCPFGGF KMSGNGRELG EYGFHEYTEV KTVTVKISQK NS

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Adrenal gland EMBL BAG56719.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK293176 mRNA. Translation: BAG56719.1.
IPI	IPI00218914.
UniGene	Hs.76392.
3D structure databases
ProteinModelPortal	B4DDF8.
ModBase	Search...
Protein-protein interaction databases
STRING	B4DDF8.
Proteomic databases
PRIDE	B4DDF8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG000097.
Gene expression databases
ArrayExpress	B4DDF8.
Bgee	B4DDF8.
Family and domain databases
Gene3D	3.40.309.10. 1 hit. 3.40.605.10. 1 hit.
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. [Graphical view]
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	B4DDF8.
NextBio	35470921.

Entry information

Entry name

B4DDF8_HUMAN

Accession

Primary (citable) accession number: B4DDF8

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.