B3WCP7 (B3WCP7_LACCB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Name:	trxB2 EMBL CAQ66148.1
Ordered Locus Names:	LCABL_10620

Organism

Lactobacillus casei (strain BL23) [Complete proteome] [HAMAP] EMBL CAQ66148.1

Taxonomic identifier

543734 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	317 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880 EMBL CAQ66148.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3WCP7 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 2373544F11148A36	FASTA	317	34,497
	10 20 30 40 50 60 MAKKYDVIVI GAGPGGMTAA LYASRANLSV LMLDRGVYGG QMNNTAEVEN YPGFKSILGP 70 80 90 100 110 120 DLGQKMYDGA TQFGAEYAYG NVVSVQNRGA VKLVKTDEDE YEAKAIVIAT GAEHKKLGVP 130 140 150 160 170 180 GEEAYSGRGV SYCAVCDGAF FKDRELAVIG GGDSAIEEGL YLTQMAKKVT VIHRRDQLRA 190 200 210 220 230 240 QQIIQKRAFA NDKMHFVWNA QVQEIQGDDM KVTGVKYRDR DKETGEEHIL PVAGVFIYVG 250 260 270 280 290 300 IMPMTEAFQD LGVLDEHGWI PTDEHMRTKV PGVFAIGDVR AKDLRQITTA VGEGGTAGQG 310 VFNYIQSLND TNIEIKA

References

[1]

"Complete genome sequence of the probiotic Lactobacillus casei strain BL23." Maze A., Boel G., Zuniga M., Bourand A., Loux V., Yebra M.J., Monedero V., Correia K., Jacques N., Beaufils S., Poncet S., Joyet P., Milohanic E., Casaragola S., Auffray Y., Perez-Martinez G., Gibrat J.F., Zagorec M. , Francke C., Hartke A., Deutscher J. J. Bacteriol. 192:2647-2648(2010) Cited for: NUCLEOTIDE SEQUENCE. Strain: BL23 EMBL CAQ66148.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM177140 Genomic DNA. Translation: CAQ66148.1.
RefSeq	YP_001987006.1. NC_010999.1.
3D structure databases
ProteinModelPortal	B3WCP7.
ModBase	Search...
Protein-protein interaction databases
STRING	B3WCP7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6405966.
GenomeReviews	Gene locus LCABL_10620 in contig FM177140_GR.
KEGG	lcb:LCABL_10620.
PATRIC	22211581. VBILacCas89204_0983.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG669726.
OMA	GEEREFP.
ProtClustDB	CLSK2462343.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3WCP7_LACCB

Accession

Primary (citable) accession number: B3WCP7

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)