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B3W7R4 (B3W7R4_LACCB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Shikimate dehydrogenase 2 HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222
Gene names
Name:aroE EMBL CAQ65669.1
Synonyms:aroE2 HAMAP MF_00222
Ordered Locus Names:LCABL_05430
OrganismLactobacillus casei (strain BL23) [Complete proteome] [HAMAP] EMBL CAQ65669.1
Taxonomic identifier543734 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222

Sequence similarities

Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding135 – 1395NADP By similarity HAMAP MF_00222

Sites

Active site751Proton acceptor By similarity HAMAP MF_00222

Sequences

Sequence LengthMass (Da)Tools
B3W7R4 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: E97D6F16ECCAD036

FASTA29931,939
        10         20         30         40         50         60 
MSLKDEIDGH TVLAGLLAHP AGHSMSPAMY NATFEKLGLN DAYLSFDVDT PELAHALQAM 

        70         80         90        100        110        120 
RSLHFLGGNL SMPNKQKAIP LLDKLSPAAK LIGAVNTIVN DHGVLTGHIT DGTGFMQALS 

       130        140        150        160        170        180 
NDGLDIRGEK MTLAGAGGAG TAIAIQAALD GVREINIFNR RDASWQNAER NVAIINDQTQ 

       190        200        210        220        230        240 
GHATLFALDD QPALKASISD SVIYVDATPA GMKPLETISN VPDGDWFTPE TIVFDTVYAP 

       250        260        270        280        290 
RETKLMQLAK EAGVNHVYNG INMLINQGAA AFHLWTGLQM PVDYIRETVF GEPAAVAHS

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References

[1]"Complete genome sequence of the probiotic Lactobacillus casei strain BL23."
Maze A., Boel G., Zuniga M., Bourand A., Loux V., Yebra M.J., Monedero V., Correia K., Jacques N., Beaufils S., Poncet S., Joyet P., Milohanic E., Casaragola S., Auffray Y., Perez-Martinez G., Gibrat J.F., Zagorec M. expand/collapse author list , Francke C., Hartke A., Deutscher J.
J. Bacteriol. 192:2647-2648(2010)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BL23 EMBL CAQ65669.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM177140 Genomic DNA. Translation: CAQ65669.1.
RefSeqYP_001986527.1. NC_010999.1.

3D structure databases

ProteinModelPortalB3W7R4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB3W7R4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6407131.
GenomeReviewsGene locus LCABL_05430 in contig FM177140_GR.
KEGGlcb:LCABL_05430.
PATRIC22210580. VBILacCas89204_0521.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG553408.
OMASIYIDAT.
ProtClustDBPRK00258.

Family and domain databases

HAMAPMF_00222. Shikimate_DH_AroE.
[Tree]
InterProIPR016040. NAD(P)-bd_dom.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00014.
PfamPF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3W7R4_LACCB
AccessionPrimary (citable) accession number: B3W7R4
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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