ID NSP6_ROTAD Reviewed; 37 AA. AC B3SRS6; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 02-SEP-2008, sequence version 1. DT 14-DEC-2022, entry version 22. DE RecName: Full=Non-structural protein 6 {ECO:0000255|HAMAP-Rule:MF_04093}; DE Short=NSP6 {ECO:0000255|HAMAP-Rule:MF_04093}; OS Rotavirus A (strain RVA/Human/United States/D/1974/G1P1A[8]) (RV-A). OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes; OC Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A. OX NCBI_TaxID=578831; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC RNA]. RX PubMed=18786998; DOI=10.1128/jvi.01402-08; RA Heiman E.M., McDonald S.M., Barro M., Taraporewala Z.F., Bar-Magen T., RA Patton J.T.; RT "Group A human rotavirus genomics: evidence that gene constellations are RT influenced by viral protein interactions."; RL J. Virol. 82:11106-11116(2008). CC -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093}. CC Host mitochondrion {ECO:0000255|HAMAP-Rule:MF_04093}. Note=Found in CC spherical cytoplasmic structures, called viral factories, that appear CC early after infection and are the site of viral replication and CC packaging. {ECO:0000255|HAMAP-Rule:MF_04093}. CC -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC -!- CAUTION: This protein is truncated. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EF672576; ABV53251.1; -; Genomic_RNA. DR Proteomes; UP000006368; Genome. DR GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell. DR HAMAP; MF_04093; ROTA_NSP6; 1. DR InterPro; IPR006950; Rotavirus_NSP6. DR Pfam; PF04866; Rota_NS6; 1. PE 3: Inferred from homology; KW Host cytoplasm; Host mitochondrion. FT CHAIN 1..37 FT /note="Non-structural protein 6" FT /id="PRO_0000369522" SQ SEQUENCE 37 AA; 4347 MW; 984E8E4C38D2D28B CRC64; MNRLLQRQLF LENLLVGTNS MFHQISKHSI NTCCRSL //