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B3S2J9 (B3S2J9_TRIAD) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histone-lysine N-methyltransferase, H3 lysine-79 specific RuleBase RU271113

EC=2.1.1.43 RuleBase RU271113
Alternative name(s):
Histone H3-K79 methyltransferase RuleBase RU271113
Gene names
ORF Names:TRIADDRAFT_58052 EMBL EDV23106.1
OrganismTrichoplax adhaerens (Trichoplax reptans) [Reference proteome]
Taxonomic identifier10228 [NCBI]
Taxonomic lineageEukaryotaMetazoaPlacozoaTrichoplax

Protein attributes

Sequence length783 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. RuleBase RU271113

Subcellular location

Nucleus By similarity RuleBase RU271113.

Miscellaneous

In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones By similarity. RuleBase RU271113

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. RuleBase RU271113

Contains 1 DOT1 domain. RuleBase RU271113

Sequences

Sequence LengthMass (Da)Tools
B3S2J9 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 4C90E65B91123C9E

FASTA78388,139
        10         20         30         40         50         60 
MAHSHRLTYR RKHRNQAQEI IDTISFVCED FVELRPAMNN NIAQFYKPES YESMSTMCEK 

        70         80         90        100        110        120 
YNRAIDGIRQ LVYGETSFSL MTQILKILNP TPDDVFIDLG SGVGQAVLQA AASTNCKECW 

       130        140        150        160        170        180 
GIEKADIPAK FAKEIDKSFR KWMKWFGKSF CKYQLVKGDF LAPEYEGLIP KCTLIFVNNF 

       190        200        210        220        230        240 
AFGPAVDHQL KQIFANLVEG AKIVSSREFM PLNFRISSRN LSDIGSMMRI EELASLRGGV 

       250        260        270        280        290        300 
SWTGKPVKYY LHTVDSTAEN NQTENLSSNG AKSTLSNFID DEGVDDVTVF ESGNANISFN 

       310        320        330        340        350        360 
SIKTSRTCEN RQEKSQKSLL DIQKIPVLNE RNSEISKIKK RKKQHSQFSI MDAKLKAGVA 

       370        380        390        400        410        420 
STDNDSEYNN LNEKVIKKLK KHQGIKLKKK EKKIKSNSIK EALTSTADAE ELINNQKNRK 

       430        440        450        460        470        480 
TIKAKISSKL GKSKKRQKNA TEGSVTKNEQ LLYNSSGIQN VHSDNVATLS KDVQYSGNHG 

       490        500        510        520        530        540 
AMPRSLLNKI THVNKHHHQA LAGYDQILTS IAQNVTLPEF QQQLKHEHDS LLQQESELTK 

       550        560        570        580        590        600 
HLKWLKSENR SLLDTNARLA DKALKEFNEI KAIVGPNVGE ISTFEPFKIN QLLSITKDST 

       610        620        630        640        650        660 
NLPFNINREG RQNKISTSSD LSCTQKTNHS VIVNGTSSPR SEVQVDYEVN NLHPEESQTI 

       670        680        690        700        710        720 
QKMKMSDYPD PNTFKANVNT NLLDNCEQLG AKSEPFDSKQ QEKASVNDSE LKLQSGYRNH 

       730        740        750        760        770        780 
CYDVKIANGI NVSNGTTELD SNHYNECTEL KTQHKSVLMN HKTPVGNNGI TENGFTTVKS 


CID 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS985247 Genomic DNA. Translation: EDV23106.1.
RefSeqXP_002114016.1. XM_002113980.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10228.JGI58052.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaTriadT58052; TriadP58052; TriadG58052.
GeneID6755558.
KEGGtad:TRIADDRAFT_58052.

Phylogenomic databases

eggNOGNOG294902.
KOK11427.
OrthoDBEOG7W6WJV.

Family and domain databases

InterProIPR013110. DOT1.
IPR025789. Histone_H3-K79_MeTrfase.
[Graphical view]
PfamPF08123. DOT1. 1 hit.
[Graphical view]
PROSITEPS51569. DOT1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3S2J9_TRIAD
AccessionPrimary (citable) accession number: B3S2J9
Entry history
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 19, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)