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Protein

DNA ligase

Gene

TRIADDRAFT_57566

Organism
Trichoplax adhaerens (Trichoplax reptans)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:TRIADDRAFT_57566Imported
OrganismiTrichoplax adhaerens (Trichoplax reptans)Imported
Taxonomic identifieri10228 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlacozoaTrichoplax
ProteomesiUP000009022 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi10228.TriadP57566.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000007653.
InParanoidiB3RZT0.
KOiK10776.
OMAiGMYSEIK.
OrthoDBiEOG7BKCT2.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR019406. Znf_C2H2_APLF-like.
IPR001510. Znf_PARP.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF10283. zf-CCHH. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3RZT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPIEFLAEYD RSGRASCKGC KQKLEKKALR IAKVVENPFG DTGETMKQWH
60 70 80 90 100
HPKCIFNSFI RARPATKIIQ TVADIDGYDD LEDDDQESVS QMITDCLKER
110 120 130 140 150
GNKQSKKKMV QQSIPFAKAY HSSTSNNNNS QDDNSFQLFT SLCDKIGNVG
160 170 180 190 200
SYLAKTKVVA DLLKMGSNGN GYEGDIYLLM KLLLPGIEKR VYNLQSRQLI
210 220 230 240 250
KLFSQIFVCD YDEMLEDLDK GDVAETITDF FANNTAVAPL NRSLLTMQEV
260 270 280 290 300
DDLLDELSNV TKEDMQLKVL KKIARRCTTE DLRYIIRLIK HDLRINAGSR
310 320 330 340 350
HILDALDKNA HAAYQASSDL RDVVDRCLAR KTDRNNDDDD GAPKLKRDLS
360 370 380 390 400
IRASLMTPVR PMLAEACKSI NTAIKKCPKG MFAEIKYDGE RVQIHKNGQQ
410 420 430 440 450
FEYYSRSLKQ VMPHKVKDIK QYLPQACPHG NSIILDSEVL LVDKTGKPLP
460 470 480 490 500
FGTLGVHKKQ NFSDATVCLF IFDCLHFNGK DLMQTRKILE SNVQEIPGRI
510 520 530 540 550
MLSEKKLVQK ENELTGLVSR VIREGLEGLV LKDVESVYEP GKRHWLKIKK
560 570 580 590 600
DYLAEGSMAD SADLVVLGAY YGTGNKGGVM SVFLMGTYDE RSGRWRTVAK
610 620 630 640 650
CGNGHDDKTL DKINKELSVV KISKDFSKVP GWLNVHRSLV PDFIVTDPKT
660 670 680 690 700
APVWEITGAE FSQSTVHTAD GISIRFPRVT RIRDDKDWTN ATNLDRLKTL
710 720 730 740 750
YENSKDASDI ADSLLGVKKE VDDEGECSSS SSPDKTVTRK RKVEELEKEK
760 770 780 790 800
TTIADNKVIS KIPCKYGPNC YRKNGEHLAN YSHNKENGNS SPNACGSQIK
810 820
QDDSSKYMTA SEFWDFYKKS KQS
Length:823
Mass (Da):92,832
Last modified:September 2, 2008 - v1
Checksum:i9D9CAEB850C94A94
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS985246 Genomic DNA. Translation: EDV23892.1.
RefSeqiXP_002113418.1. XM_002113382.1.

Genome annotation databases

EnsemblMetazoaiTriadT57566; TriadP57566; TriadG57566.
GeneIDi6754999.
KEGGitad:TRIADDRAFT_57566.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS985246 Genomic DNA. Translation: EDV23892.1.
RefSeqiXP_002113418.1. XM_002113382.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10228.TriadP57566.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiTriadT57566; TriadP57566; TriadG57566.
GeneIDi6754999.
KEGGitad:TRIADDRAFT_57566.

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000007653.
InParanoidiB3RZT0.
KOiK10776.
OMAiGMYSEIK.
OrthoDBiEOG7BKCT2.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR019406. Znf_C2H2_APLF-like.
IPR001510. Znf_PARP.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF10283. zf-CCHH. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Grell-BS-1999Imported.

Entry informationi

Entry nameiB3RZT0_TRIAD
AccessioniPrimary (citable) accession number: B3RZT0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 22, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.