B3RVD3 (B3RVD3_TRIAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
GMP reductase RuleBase RU003929
EC=1.7.1.7 RuleBase RU003929

Gene names

ORF Names:

TRIADDRAFT_63276 EMBL EDV25974.1

Organism

Trichoplax adhaerens (Trichoplax reptans) [Complete proteome]

Taxonomic identifier

10228 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Placozoa › Trichoplax

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides By similarity. RuleBase RU003929
Catalytic activity	Inosine 5'-phosphate + NH3 + NADP+ = guanosine 5'-phosphate + NADPH. RuleBase RU003929
Sequence similarities	Belongs to the IMPDH/GMPR family. RuleBase RU003927

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003929 NADP RuleBase RU003929 Potassium RuleBase RU003929
Molecular function	Oxidoreductase RuleBase RU003927
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	GMP reductase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B3RVD3 [UniParc]. Last modified September 2, 2008. Version 1. Checksum: 74CF830D0E0C28F0	FASTA	349	37,912
	10 20 30 40 50 60 MPRIDNDIKL DFKDVLFRPK RSTLKSRSEV ELVRKLQFRN SGNSYEGIPI IAANMDTTGT 70 80 90 100 110 120 FEVAEALAMH KMFTAIHKHY SLQQWQDFAN DHKDVLQYVA VSSGASKDDM DRLDAILSAV 130 140 150 160 170 180 PALNTICLDV ANGYSELFVE CVRNVRKKYP NHTVIAGNVV TGEMVEELIL SGADIIKVGI 190 200 210 220 230 240 GPGSVCTTRK KTGVGYPQIS AVLECADAAH GLGGHIISDG GCTCPGDVAK AFGAGADFVM 250 260 270 280 290 300 LGGMFAGHDQ SGGELIETNG KKVKLFYGMS SAVAMHKYVG KVAEYRASEG KCVEIPYRGD 310 320 330 340 INDTVLDVLG GVRSTCTYVG ASKLKELSKR TTFIRVTQQL NEIFKQNEK

References

[1]

"The Trichoplax genome and the nature of placozoans." Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U., Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L., Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J., Shapiro H., Grigoriev I.V., Buss L.W. , Schierwater B., Dellaporta S.L., Rokhsar D.S. Nature 454:955-960(2008) [PubMed: 18719581] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Grell-BS-1999 EMBL EDV25974.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS985244 Genomic DNA. Translation: EDV25974.1.
RefSeq	XP_002112007.1. XM_002111971.1.
3D structure databases
ProteinModelPortal	B3RVD3.
ModBase	Search...
Protein-protein interaction databases
STRING	B3RVD3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	TriadT63276; TriadP63276; TriadG63276.
GeneID	6752728.
KEGG	tad:TRIADDRAFT_63276.
Phylogenomic databases
OMA	FRNSKQM.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR005993. GMP_reduct1. IPR015875. IMP_DH/GMP_Rdtase_CS. IPR001093. IMP_DH_GMPRt. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00364.
Pfam	PF00478. IMPDH. 1 hit. [Graphical view]
PIRSF	PIRSF000235. GMP_reductase. 1 hit.
TIGRFAMs	TIGR01305. GMP_reduct_1. 1 hit.
PROSITE	PS00487. IMP_DH_GMP_RED. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B3RVD3_TRIAD

Accession

Primary (citable) accession number: B3RVD3

Entry history

Integrated into UniProtKB/TrEMBL:	September 2, 2008
Last sequence update:	September 2, 2008
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)