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Protein

Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog

Gene

TRIADDRAFT_20668

Organism
Trichoplax adhaerens (Trichoplax reptans)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.UniRule annotation

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytosolic iron-sulfur protein assembly protein CIAO1 homologUniRule annotation
Gene namesi
ORF Names:TRIADDRAFT_20668
OrganismiTrichoplax adhaerens (Trichoplax reptans)
Taxonomic identifieri10228 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlacozoaTrichoplax
Proteomesi
  • UP000009022 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003824981 – 313Probable cytosolic iron-sulfur protein assembly protein CIAO1 homologAdd BLAST313

Interactioni

Protein-protein interaction databases

STRINGi10228.TriadP20668.

Structurei

3D structure databases

ProteinModelPortaliB3RNR8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1 – 35WD 1Add BLAST35
Repeati43 – 82WD 2Add BLAST40
Repeati87 – 126WD 3Add BLAST40
Repeati133 – 172WD 4Add BLAST40
Repeati177 – 216WD 5Add BLAST40
Repeati227 – 266WD 6Add BLAST40
Repeati277 – 313WD 7Add BLAST37

Sequence similaritiesi

Belongs to the WD repeat CIA1 family.UniRule annotation
Contains 7 WD repeats.UniRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG0645. Eukaryota.
ENOG410XRMA. LUCA.
HOGENOMiHOG000208901.
InParanoidiB3RNR8.
OMAiDRTVWVW.
OrthoDBiEOG091G0AAM.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_03037. ciao1. 1 hit.
InterProiIPR028608. CIAO1/Cia1.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 5 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B3RNR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTVAFLPLS FPFLIFNFGQ YIRIWAKNSD SDQWTCKSIL TEGHTRTIRS
60 70 80 90 100
VAWSPCGNYL ASCSFDATIC IWSKKDGDFE CMATLEGHEN EVKCVNWSSS
110 120 130 140 150
GVYLASCSRD KSAWIWEFIE EDEEYECASV LTDHSQDVKH VVWSPKENAL
160 170 180 190 200
VSASYDNTIK IYKEVDDDWE CSHTLIGHES TVWSLSFHSS GELFVSCGDD
210 220 230 240 250
KVLKIWKCLK SGPSDVKWIS ICTIAGYHNR PIYDVDWSKL NNKIATACGD
260 270 280 290 300
DAIRIFSIVR ITISISNQLL FIAYYQAHNH DVNVVRWHPK VDNILASGSD
310
DNCIKIWKVH SNN
Length:313
Mass (Da):35,608
Last modified:September 2, 2008 - v1
Checksum:i0B4D3A4217199FD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS985242 Genomic DNA. Translation: EDV28061.1.
RefSeqiXP_002109895.1. XM_002109859.1.

Genome annotation databases

EnsemblMetazoaiTriadT20668; TriadP20668; TriadG20668.
GeneIDi6751110.
KEGGitad:TRIADDRAFT_20668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS985242 Genomic DNA. Translation: EDV28061.1.
RefSeqiXP_002109895.1. XM_002109859.1.

3D structure databases

ProteinModelPortaliB3RNR8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10228.TriadP20668.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiTriadT20668; TriadP20668; TriadG20668.
GeneIDi6751110.
KEGGitad:TRIADDRAFT_20668.

Phylogenomic databases

eggNOGiKOG0645. Eukaryota.
ENOG410XRMA. LUCA.
HOGENOMiHOG000208901.
InParanoidiB3RNR8.
OMAiDRTVWVW.
OrthoDBiEOG091G0AAM.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_03037. ciao1. 1 hit.
InterProiIPR028608. CIAO1/Cia1.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 5 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00320. WD40. 6 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 5 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCIAO1_TRIAD
AccessioniPrimary (citable) accession number: B3RNR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: September 2, 2008
Last modified: November 30, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.