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Reviewed, UniProtKB/Swiss-Prot B3RBL3 (F16A2_CUPTR)

Last modified November 3, 2009. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Fructose-1,6-bisphosphatase class 1 2
      Short name=FBPase class 1 2
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2
Gene names
Name: fbp2
Ordered Locus Names: RALTA_B1696
OrganismCupriavidus taiwanensis (strain R1 / LMG 19424) (Ralstonia taiwanensis (strain LMG 19424)) [Complete proteome] [HAMAP]
Taxonomic identifier164546 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

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Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the FBPase class 1 family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 364364Fructose-1,6-bisphosphatase class 1 2 HAMAP MF_01855
PRO_0000364531

Regions

Region126 – 1294Substrate binding By similarity

Sites

Metal binding1011Magnesium 1 By similarity
Metal binding1231Magnesium 1 By similarity
Metal binding1231Magnesium 2 By similarity
Metal binding1251Magnesium 1; via carbonyl oxygen By similarity
Metal binding1261Magnesium 2 By similarity
Metal binding2901Magnesium 2 By similarity
Binding site2181Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
B3RBL3-1 [UniParc].

Last modified September 2, 2008. Version 1.
Checksum: 64A5C93587FAF1C3

FASTA36439,828
        10         20         30         40         50         60 
MPEVQRMTLT QFLIEQRRRY PDASGGFNGL ILNVAMACKE IARAVAFGAL GGLHGRAGGP 

        70         80         90        100        110        120 
DAAGAAINVQ GEVQQKLDVL SNDTFLRVNE WGGYLAGMAS EEMEAPYQIP AHYPRGKYLL 

       130        140        150        160        170        180 
VFDPLDGSSN IDVNVSVGSI FSVLRAPEGT ADVTEQAFLQ PGTAQVAAGY ALYGPTTMLV 

       190        200        210        220        230        240 
LTVGNGVNGF TLDPNLGEFF LTHPDLRVPA DTREFAINAS NSRFWEAPIR QYVSECLAGQ 

       250        260        270        280        290        300 
TGPRGKDFNM RWIASMVAEA HRILMRGGVF MYPRDTKDPA RPGRLRLLYE ANPIAFLMEQ 

       310        320        330        340        350        360 
AGGRASTGRQ ALMSVAPNAL HQRIGVIFGS RHEVERIERY HNEQTDPDLP NPLFNERSLF 


RASA

« Hide

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References

[1]"Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia."
Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D., Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., Poinsot V., Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., Batut J., Medigue C., Masson-Boivin C.
Genome Res. 18:1472-1483(2008) [PubMed: 18490699] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CU633750 Genomic DNA. Translation: CAQ72288.1.
RefSeqYP_002008342.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6456655.
GenomeReviewsGene locus RALTA_B1696 in contig CU633750_GR.
KEGGcti:RALTA_B1696.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAIFLYPGN.

Family and domain databases

HAMAPMF_01855.
[Tree]
InterProIPR000146. Fructose_bisphosphatase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameF16A2_CUPTR
AccessionPrimary (citable) accession number: B3RBL3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 2, 2008
Last modified: November 3, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents